1.
J Org Chem
; 82(4): 2205-2210, 2017 02 17.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28103439
RESUMEN
A tandem Michael-Henry reaction of 2-mercaptoquinoline-3-carbaldehydes with nitroolefins using hydrogen-bonding-based cooperative organocatalysts for the highly diastereodivergent synthesis of chiral functionalized 3,4-dihydro-2H-thiopyrano[2,3-b]quinolines with three contiguous tertiary stereocenters has been developed.