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1.
Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl-xL silenced cells.
Mol Carcinog
; 57(4): 469-482, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29240261
2.
Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in Bcl-xL silenced glioma cell lines.
Mol Carcinog
; 56(4): 1251-1265, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27805285
3.
Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines.
J Pharmacol Exp Ther
; 356(2): 354-65, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26585571
4.
Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells.
J Pharmacol Exp Ther
; 350(1): 22-35, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24741074
5.
Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.
J Neurooncol
; 120(3): 459-72, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25139025
6.
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Cell Rep
; 43(1): 113557, 2024 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38113141
7.
Survivin inhibitor YM-155 sensitizes tumor necrosis factor- related apoptosis-inducing ligand-resistant glioma cells to apoptosis through Mcl-1 downregulation and by engaging the mitochondrial death pathway.
J Pharmacol Exp Ther
; 346(2): 201-10, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23740602
8.
Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage.
Mol Carcinog
; 52(2): 118-33, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22086447
9.
Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediatric and adult high-grade gliomas.
Mol Oncol
; 17(9): 1821-1843, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37014128
10.
ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines.
J Pharmacol Exp Ther
; 341(3): 859-72, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22393246
11.
Reversing tozasertib resistance in glioma through inhibition of pyruvate dehydrogenase kinases.
Mol Oncol
; 16(1): 219-249, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34058053
12.
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nat Cancer
; 3(5): 629-648, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35422502
13.
Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells.
J Carcinog
; 92010 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20808823
14.
Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.
Mol Cancer Res
; 18(7): 1004-1017, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32238439
15.
Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells.
J Pharmacol Exp Ther
; 331(1): 327-37, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19622715
16.
AG490 influences UCN-01-induced cytotoxicity in glioma cells in a p53-dependent fashion, correlating with effects on BAX cleavage and BAD phosphorylation.
Cancer Lett
; 257(1): 36-46, 2007 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-17900801
17.
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nat Cancer
; 3(7): 899, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35739422
18.
Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis.
J Neurosurg
; 103(6 Suppl): 549-56, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16383255
19.
Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells.
Cancer Biol Ther
; 16(2): 233-43, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25482928
20.
NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5.
Int J Oncol
; 47(2): 506-16, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26044191