RESUMEN
BACKGROUND: Parry-Romberg syndrome (PRS) is a rare disorder characterized by unilateral facial atrophy affecting the skin, subcutaneous tissue, muscles, and sometimes extending to the osteocartilaginous structures. Ocular involvement is relatively rare. CASE PRESENTATION: We present a case of a 23-year-old female caucasian patient with Parry Romberg syndrome and extensive ocular involvement: enophthalmos, uveitis, iris atrophy. Ultrasound biomicroscopy (UBM) demonstrated hypotrophy of the ciliary body. The ciliary body atrophy has been previously reported just once and can be an explanation for the hypotony, frequently present in these patients. CONCLUSIONS: Parry Romberg syndrome is a rare multidisciplinary disease. Our case presents a full spectrum of ocular manifestations. The pathogenesis of hypotonia is discussed.
Asunto(s)
Cuerpo Ciliar/patología , Enoftalmia/diagnóstico , Hemiatrofia Facial/diagnóstico , Iris/patología , Uveítis/diagnóstico , Atrofia/diagnóstico por imagen , Cuerpo Ciliar/diagnóstico por imagen , Femenino , Humanos , Imagenología Tridimensional , Iris/diagnóstico por imagen , Microscopía Acústica , Tomografía Computarizada por Rayos X , Adulto JovenRESUMEN
OBJECTIVE: This paper presents an integrated device, based on smart glasses, for the pattern-reversal visual evoked potential (PR-VEP) clinical test. METHODS: Smart glasses are used to generate the checkerboard changing pattern, with its related red fixation point through an Android application. Electroencephalographic signals, for monitoring the stimulus generated by PR-VEP, were amplified close to the scalp and then transmitted wirelessly to a PC. A MATLAB real-time algorithm processed the incoming signals to extract the final PR-VEP signal. METHODS: In total, 40 eyes (from 20 subjects, 12 males and 8 females between 24 and 28 years old) were tested and results were compared, with a commercial device for VEP clinical exam, to test the reproducibility and the efficacy of the proposed solution. RESULTS: PR-VEPs generated by smart glasses showed typical triphasic waveforms: We observed promising results and components in moderate agreement with those obtained using commercial PR-VEP recorder, with potential for improvements after further refinement works. SIGNIFICANCE: The proposed device leads the way for a portable and low-cost solution.