RESUMEN
One hundred and forty seven cases of pseudocondyloma, which were diagnosed by colposcopy and histopathology, and 129 cases of condyloma as control group were studied. Pseudocondyloma showed colposcopically as crowded together distribution of single papilla or vesiculated papules without branching structure and capillary loops. The color of the lesions is unchanged after acetic acid stain. The lesions can be divided into vesicular proliferative type and ciliary proliferative type. Differing from condyloma, pseudocondyloma lesions showed histopathologically only slight proliferation of squamous epithelium, lack of diagnostic koilocytes and negative result in HPV immunohistochemical study and hybridization of HPV-DNA. It is a reliable method to make a diagnosis of pseudocondyloma by colposcopy and histopathology.