Detalles de la búsqueda
1.
Solvent-Casted Films to Assist Polymer Selection for Amorphous Solid Dispersions During Preclinical Studies: In-vitro and In-vivo Exploration.
Pharm Res
; 38(5): 901-914, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33880721
2.
An integrated Qual/Quan strategy for ganglioside lipidomics using high-resolution mass spectrometry and Skyline software.
Rapid Commun Mass Spectrom
; 35(7): e9041, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33415785
3.
Development of BET inhibitors as potential treatments for cancer: A search for structural diversity.
Bioorg Med Chem Lett
; 44: 128108, 2021 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33991625
4.
Fucosyl monosialoganglioside: Quantitative analysis of specific potential biomarkers of lung cancer in biological matrices using immunocapture extraction/tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 32(17): 1481-1490, 2018 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29876976
5.
BMS-871: a novel orally active pan-Notch inhibitor as an anticancer agent.
Bioorg Med Chem Lett
; 25(9): 1905-9, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25857941
6.
Strategy to improve the quantitative LC-MS analysis of molecular ions resistant to gas-phase collision induced dissociation: application to disulfide-rich cyclic peptides.
Anal Chem
; 86(23): 11523-7, 2014 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25371986
7.
Quantification of Linrodostat and its metabolites: Overcoming bioanalytical challenges in support of a discovery Indoleamine 2,3 dioxygenase program.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1207: 123305, 2022 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35839627
8.
Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1.
ACS Med Chem Lett
; 12(2): 288-294, 2021 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33603977
9.
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
ACS Med Chem Lett
; 12(7): 1143-1150, 2021 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34267885
10.
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
J Med Chem
; 64(19): 14247-14265, 2021 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34543572
11.
Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride.
Cancer Res
; 62(18): 5183-8, 2002 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12234982
12.
Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride.
Cancer Res
; 62(18): 5189-95, 2002 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12234983
13.
Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors.
ACS Med Chem Lett
; 6(5): 523-7, 2015 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26005526
14.
Exposure-dependent accumulation of N-(2-hydroxypropyl)valine in hemoglobin of F344 rats exposed to propylene oxide by the inhalation route.
J Chromatogr B Analyt Technol Biomed Life Sci
; 778(1-2): 383-91, 2002 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12376143
15.
Biomarkers in Czech workers exposed to 1,3-butadiene: a transitional epidemiologic study.
Res Rep Health Eff Inst
; (116): 1-141; discussion 143-62, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12931846
16.
Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties.
J Med Chem
; 56(23): 9586-600, 2013 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24182233
17.
Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS.
Bioanalysis
; 4(5): 511-28, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22409550
18.
Development of an on-line automated sample clean-up method and liquid chromatography-tandem mass spectrometry analysis: application in an in vitro proteolytic assay.
Anal Bioanal Chem
; 384(5): 1145-54, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16468024
19.
Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry.
Chem Res Toxicol
; 18(1): 51-60, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15651849
20.
Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry.
Anal Chem
; 74(18): 4734-40, 2002 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12349977