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1.
Arch Ital Urol Androl ; 91(4): 267-268, 2020 Jan 14.
Artículo en Inglés | MEDLINE | ID: mdl-31937095

RESUMEN

A case of right open nephrectomy performed under combined spinal and epidural anesthesia and analgesia was presented. This new anesthetic technique gives significant advantages to the patient by avoiding endotracheal intubation with mechanical ventilation and curare administration and by reducing the use of opioids.


Asunto(s)
Anestesia Epidural/métodos , Anestesia Raquidea/métodos , Nefrectomía/métodos , Humanos , Masculino , Persona de Mediana Edad
2.
AJNR Am J Neuroradiol ; 38(10): 1858-1865, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28495940

RESUMEN

This is the second part of a retrospective and review MR imaging study aiming to define the frequency rate, timing, imaging features, and evolution of gray matter changes in Menkes disease, a rare multisystem X-linked disorder of copper metabolism characterized by early, severe, and progressive neurologic involvement. According to our analysis, neurodegenerative changes and focal basal ganglia lesions already appear in the early phases of the disease. Subdural collections are less common than generally thought; however, their presence remains important because they might challenge the differential diagnosis with child abuse and might precipitate the clinical deterioration. Anecdotal findings in our large sample seem to provide interesting clues about the protean mechanisms of brain injury in this rare disease and further highlight the broad spectrum of MR imaging findings that might be expected while imaging a child with the suspicion of or a known diagnosis of Menkes disease.


Asunto(s)
Encéfalo/diagnóstico por imagen , Encéfalo/patología , Síndrome del Pelo Ensortijado/diagnóstico por imagen , Síndrome del Pelo Ensortijado/patología , Neuroimagen , Niño , Sustancia Gris/diagnóstico por imagen , Sustancia Gris/patología , Humanos , Imagen por Resonancia Magnética , Masculino , Estudios Retrospectivos
3.
AJNR Am J Neuroradiol ; 38(10): 1850-1857, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28495946

RESUMEN

Menkes disease is a rare multisystem X-linked disorder of copper metabolism. Despite an early, severe, and progressive neurologic involvement, our knowledge of brain involvement remains unsatisfactory. The first part of this retrospective and review MR imaging study aims to define the frequency rate, timing, imaging features, and evolution of intracranial vascular and white matter changes. According to our analysis, striking but also poorly evolutive vascular abnormalities characterize the very early phases of disease. After the first months, myelination delay becomes evident, often in association with protean focal white matter lesions, some of which reveal an age-specific brain vulnerability. In later phases of the disease, concomitant progressive neurodegeneration might hinder the myelination progression. The currently enriched knowledge of neuroradiologic finding evolution provides valuable clues for early diagnosis, identifies possible MR imaging biomarkers of new treatment efficacy, and improves our comprehension of possible mechanisms of brain injury in Menkes disease.


Asunto(s)
Encéfalo/diagnóstico por imagen , Encéfalo/patología , Síndrome del Pelo Ensortijado/diagnóstico por imagen , Síndrome del Pelo Ensortijado/patología , Neuroimagen , Progresión de la Enfermedad , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Estudios Retrospectivos , Sustancia Blanca/diagnóstico por imagen , Sustancia Blanca/patología
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