A registered report of a two-site study of variations of the flanker task: ERN experimental effects and data quality.

Error-related negativity is a widely used measure of error monitoring, and many projects are independently moving ERN recorded during a flanker task toward standardization, optimization, and eventual clinical application. However, each project uses a different version of the flanker task and tacitly assumes ERN is functionally equivalent across each version. The routine neglect of a rigorous test of this assumption undermines efforts to integrate ERN findings across tasks, optimize and standardize ERN assessment, and widely apply ERN in clinical trials. The purpose of this registered report was to determine whether ERN shows similar experimental effects (correct vs. error trials) and data quality (intraindividual variability) during three commonly used versions of a flanker task. ERN was recorded from 172 participants during three versions of a flanker task across two study sites. ERN scores showed numerical differences between tasks, raising questions about the comparability of ERN findings across studies and tasks. Although ERN scores from all three versions of the flanker task yielded high data quality and internal consistency, one version did outperform the other two in terms of the size of experimental effects and the data quality. Exploratory analyses of the error positivity (Pe) provided tentative support for the other two versions of the task over the paradigm that appeared optimal for ERN. The present study provides a roadmap for how to statistically compare psychometric characteristics of ERP scores across paradigms and gives preliminary recommendations for flanker tasks to use for ERN- and Pe-focused studies.

The data-processing multiverse of event-related potentials (ERPs): A roadmap for the optimization and standardization of ERP processing and reduction pipelines.

In studies of event-related brain potentials (ERPs), numerous decisions about data processing are required to extract ERP scores from continuous data. Unfortunately, the systematic impact of these choices on the data quality and psychometric reliability of ERP scores or even ERP scores themselves is virtually unknown, which is a barrier to the standardization of ERPs. The aim of the present study was to optimize processing pipelines for the error-related negativity (ERN) and error positivity (Pe) by considering a multiverse of data processing choices. A multiverse analysis of a data processing pipeline examines the impact of a large set of different reasonable choices to determine the robustness of effects, such as the impact of different decisions on between-trial standard deviations (i.e., data quality) and between-condition differences (i.e., experimental effects). ERN and Pe data from 298 healthy young adults were used to determine the impact of different methodological choices on data quality and experimental effects (correct vs. error trials) at several key stages: highpass filtering, lowpass filtering, ocular artifact correction, reference, baseline adjustment, scoring sensors, and measurement procedure. This multiverse analysis yielded 3,456 ERN scores and 576 Pe scores per person. An optimized pipeline for ERN included a 15 Hz lowpass filter, ICA-based ocular artifact correction, and a region of interest (ROI) approach to scoring. For Pe, the optimized pipeline included a 0.10 Hz highpass filter, 30 Hz lowpass filter, regression-based ocular artifact correction, a -200 to 0 ms baseline adjustment window, and an ROI approach to scoring. The multiverse approach can be used to optimize pipelines for eventual standardization, which would support efforts toward establishing normative ERP databases. The proposed process of analyzing the data-processing multiverse of ERP scores paves the way for better refinement, identification, and selection of data processing parameters, ultimately improving the precision and utility of ERPs.

Susceptibility to Spear-Phishing Emails: Effects of Internet User Demographics and Email Content.

Phishing is fundamental to cyber attacks. This research determined the effect of Internet user age and email content such as weapons of influence (persuasive techniques that attackers can use to lure individuals to fall for an attack) and life domains (a specific topic or aspect of an individual's life that attackers can focus an emails on) on spear-phishing (targeted phishing) susceptibility. One-hundred young and 58 older users received, without their knowledge, daily simulated phishing emails over 21 days. A browser plugin recorded their clicking on links in the emails as an indicator of their susceptibility. Forty-three percent of users fell for the simulated phishing emails, with older women showing the highest susceptibility. While susceptibility in young users declined across the study, susceptibility in older users remained stable. The relative effectiveness of the attacks differed by weapons of influence and life domains with age-group variability. In addition, older compared to young users reported lower susceptibility awareness. These findings support effects of Internet user demographics and email content on susceptibility to phishing and emphasize the need for personalization of the next generation of security solutions.

Understanding the Error in Psychopathology: Notable Intraindividual Differences in Neural Variability of Performance Monitoring.

BACKGROUND: Abnormal performance monitoring is a possible transdiagnostic marker of psychopathology. Research on neural indices of performance monitoring, including the error-related negativity (ERN), typically examines group and interindividual (between-person) differences in mean/average scores. Intraindividual (within-person) variability in activity captures the capacity to dynamically adjust from moment to moment, and excessive variability appears maladaptive. Intraindividual variability in ERN represents a unique and largely unexamined dimension that might impact functioning. We tested whether psychopathology group differences (major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder) or corresponding psychiatric symptoms account for intraindividual variability in single-trial ERN scores. METHODS: High-density electroencephalogram was recorded during a semantic flanker task in 51 participants with major depressive disorder, 44 participants with generalized anxiety disorder, 31 participants with obsessive-compulsive disorder, and 56 psychiatrically healthy participants. Time-window mean ERN amplitude was scored 0-125 ms following participant response across four frontocentral sites. Multilevel location-scale models were used to simultaneously examine interindividual and intraindividual differences in ERN. RESULTS: Analyses indicated considerable intraindividual variability in ERN that was common across groups. However, we did not find strong evidence to support relationships between ERN and psychopathology groups or transdiagnostic symptoms. CONCLUSIONS: These findings point to important methodological implications for studies of performance monitoring in healthy and clinical populations-the common assumption of fixed intraindividual variability (i.e., residual variance) may be inappropriate for ERN studies. Implementation of multilevel location-scale models in future research can leverage between-person differences in intraindividual variability in performance monitoring to gain a rich understanding of trial-to-trial performance monitoring dynamics.

Single-session label training alters neural competition between objects and faces.

The extent to which visuocortical processing is altered when observers learn to categorize novel visual stimuli via labeling is not well understood. The present investigation used steady state visual evoked potential (ssVEP) frequency tagging to test the hypothesis that learning to categorize novel objects via labeling prompts a competitive advantage over concurrently presented stimuli. In the learning (label-training) phase, participants (n = 24) categorized objects according to two different species labels and faces according to gender. A control group (n = 26) viewed the same stimuli without label learning. Before and after learning, faces and objects were superimposed and viewed concurrently while periodically turned on and off at unique temporal rates (5/s or 6/s). The spectral power of the ssVEP at each frequency was projected to an L2 (minimum) norm estimated source space, and competition between faces and objects was compared using permutation-controlled mass univariate t tests. Results showed that, only in the training group, learning to label novel objects led to a competitive advantage over faces across a network of occipito-temporal and fronto-parietal cortical regions. These changes were more pronounced in participants showing more improvement across the label learning phase. Together, the findings support the notion that learning to label novel object categories affects neural competition though recurrent neural interactions in regions commonly associated with visual perception and selective attention. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

No intermodal interference effects of threatening information during concurrent audiovisual stimulation.

Changes in attention can result in sensory processing trade-off effects, in which sensory cortical responses to attended stimuli are heightened and responses to competing distractors are attenuated. However, it is unclear if competition or facilitation effects will be observed at the level of sensory cortex when attending to competing stimuli in two modalities. The present study used electroencephalogram (EEG) and frequency-tagging to quantitatively assess auditory-visual interactions during sustained multimodal sensory stimulation. The emotional content of a 6.66 Hz rapid serial visual presentation (RSVP) was manipulated to elicit well-established emotional attention effects, while a constant 63 dB tone with a 40.8 Hz modulation served as a concurrent auditory stimulus in two experiments. As a directed attention manipulation, participants were instructed to detect transient sound level events in the auditory stream in Experiment 1. To manipulate attention through threat anticipation, participants were instructed to expect an aversive noise burst after a higher 40.8 Hz modulated tone in Experiment 2. Each stimulus evoked reliable steady-state sensory cortical responses in all participants (n = 30) in both experiments. The visual cortical responses were modulated by the auditory detection task, but not by threat anticipation: Visual responses were smaller during auditory streams with a transient target as compared to uninterrupted auditory streams. Conversely, visual stimulus condition had no significant effects on auditory sensory cortical responses in either experiment. These results indicate that there is neither a competition nor facilitation effect of visual content on concurrent auditory sensory cortical processing. They further indicate that competition effects of auditory stream content on sustained visuocortical responses are limited to auditory target processing.

Re-test reliability and internal consistency of EEG alpha-band oscillations in older adults with chronic knee pain.

OBJECTIVE: Chronic pain studies investigating the ability to detect sensory processing differences related to thalamic gating using electroencephalographic (EEG) alpha have yielded conflicting results. Alpha's basic psychometric properties in pain populations requires further study. The present study reports on the test-retest reliability and internal consistency of EEG alpha power in older adults with chronic knee pain. METHODS: Repeated EEG alpha power measurements were taken of older adults (N = 31) with chronic knee pain across two sessions separated by a ten-day period associated with a pilot clinical trial study. Recordings included resting periods (eyes open and eyes closed) as well as periods involving a pain management activity. RESULTS: Most single alpha-power measures and all within-participant averages of alpha obtained within a session showed high internal consistency (Cronbach's α > 0.7) and satisfactory-to-excellent re-test reliability (Pearson's rs > 0.6) of both alpha power and alpha blocking (eyes closed minus eyes open) across repeated conditions. CONCLUSIONS: EEG alpha power seems mostly reliable and consistent, particularly when participants' eyes are closed, after a period of habituation, and when alpha measures are averaged as within-participant estimates. SIGNIFICANCE: This analysis suggests that within-subject averages of EEG alpha are the most reliable for developing indices of chronic knee pain.

Uncovering Susceptibility Risk to Online Deception in Aging.

OBJECTIVES: Fraud in the aged is an emerging public health problem. An increasingly common form of deception is conducted online. However, identification of cognitive and socioemotional risk factors has not been undertaken yet. In this endeavor, this study extended previous work suggesting age effects on susceptibility to online deception. METHODS: Susceptibility was operationalized as clicking on the link in simulated spear-phishing emails that young (18-37 years), young-old (62-74 years), and middle-old (75-89 years) Internet users received, without knowing that the emails were part of the study. Participants also indicated for a set of spear-phishing emails how likely they would click on the embedded link (susceptibility awareness) and completed cognitive and socioemotional measures to determine susceptibility risk profiles. RESULTS: Higher susceptibility was associated with lower short-term episodic memory in middle-old users and with lower positive affect in young-old and middle-old users. Greater susceptibility awareness was associated with better verbal fluency in middle-old users and with greater positive affect in young and middle-old users. DISCUSSION: Short-term memory, verbal fluency, and positive affect in middle-old age may contribute to resilience against online spear-phishing attacks. These results inform mechanisms of online fraud susceptibility and real-life decision-supportive interventions toward fraud risk reduction in aging.

Association of pleasant sensations at cigarette smoking initiation with subsequent tobacco product use among U.S. adolescents.

Approximately 20% of high school students and 7% of middle school students in the United States used tobacco products in 2016. One factor that may contribute to tobacco use is pleasant sensations - typically characterized as physiological reinforcement such as a dopamine response, or as social reinforcement such as social acceptance. In the present study, the Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health (PATH) Study was analyzed to examine the influence of pleasant sensations at cigarette smoking initiation on current use of other tobacco products among adolescents. While those who reported higher unpleasant sensations at cigarette smoking initiation were less likely to report current use of any tobacco product(s) (Odds Ratio [OR] = 0.70), those who reported higher pleasant sensations at cigarette initiation were more likely to report current use of any tobacco product(s) (OR = 2.12) - including: cigarettes (OR = 2.09), cigars (OR = 1.58), hookah (OR = 1.37), and e-cigarettes (OR = 1.37). Based on these findings, interventions for smoking education and further surveillance may benefit adolescents who report higher pleasant sensations at cigarette smoking initiation.