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1.
Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolideâ A.
Angew Chem Int Ed Engl
; 57(34): 11020-11024, 2018 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29943519
2.
Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28584149
3.
Discovery and Structure-Activity Relationship of Cadazolid: A First-In-Class Quinoxolidinone Antibiotic for the Treatment of Clostridioides difficile Infection.
J Med Chem
; 2024 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38753983
4.
Synthesis and Structure-Activity Relationship of Xenocoumacin 1 and Analogues as Inhibitors of Ribosomal Protein Synthesis.
ChemMedChem
; 16(5): 891-897, 2021 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33236408
5.
Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration.
J Med Chem
; 63(1): 88-102, 2020 01 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31804829
6.
Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria.
J Med Chem
; 63(1): 66-87, 2020 01 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31804826
7.
Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic.
Sci Rep
; 9(1): 5634, 2019 04 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30948752
8.
Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
J Med Chem
; 60(9): 3755-3775, 2017 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28406299
9.
Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria.
J Med Chem
; 60(9): 3776-3794, 2017 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28406300
10.
Novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram positive activity and improved safety profile.
J Med Chem
; 58(2): 927-42, 2015 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-25494934
11.
Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.
J Med Chem
; 56(18): 7396-415, 2013 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23968485
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