Barriers and facilitators to access sexual and reproductive health services among young migrants in Tarapacá, Chile: a qualitative study.

BACKGROUND: Chile has become a destination country for immigrants from Latin America, including youth. Guaranteeing access and use of sexual and reproductive health services for young migrants is crucial because of their overlapping experiences of transitioning to a new country and to adulthood. However, the existing evidence shows barriers to accessing sexual and reproductive healthcare among young migrant populations. In this context, the main objective of this article is to identify the barriers and facilitators that young migrants experience to access sexual and reproductive healthcare in the Tarapacá region of Chile. METHODS: A qualitative study was conducted in the Tarapacá region of Chile. Semi-structured interviews with 25 young migrants from Venezuela, Colombia, and Ecuador, as well as 10 health workers, were carried out. The interviews were transcribed and thematically analysed. The study was approved by the Ethics Committee of the Universidad del Desarrollo (#2019-22). RESULTS: Young migrants face barriers linked to structural shortcomings within the healthcare system, which may be similar to those faced by the local population. Barriers are also derived from reductionist sexual and reproductive health approaches, which prioritise the prevention of pregnancy, sexually transmitted infections, and HIV, with a predominantly heteronormative focus. The prevailing narratives from the health system are those of risk and lack of control and self-care among young people, and they are exacerbated in the case of migrants. Young migrants, especially from the Caribbean, are stereotyped as over-sexualised and liberal in comparison to the local population and believed to be engaging in riskier sexual behaviours that should be kept under check. This may translate into experiences of discrimination and mistreatment when receiving care. Facilitators include good-quality information and community-level interventions. CONCLUSIONS: This study shows a limited approach to the sexual and reproductive health of young migrants in Chile, severely hampering their reproductive and sexual rights. Policies and initiatives must work towards removing structural barriers, changing narratives, and empowering young migrants regarding their sexual and reproductive health.

Intersectoral strategies between health and education for preventing adolescent pregnancy in Chile: Findings from a qualitative study.

BACKGROUND: In Chile, despite its steady decrease overall, adolescent pregnancy is concentrated in the most vulnerable population. Efforts in intersectoral collaboration between health and education to address the problem are being developed, but they have not been assessed. OBJECTIVE: To describe intersectoral strategies between health and education to address adolescent sexual and reproductive health, prevent adolescent pregnancy, and to explore adolescents' and health professionals' perceptions regarding those strategies. DESIGN: A qualitative ethnographic study was carried out in five municipalities in the Metropolitan Region of Chile. A sample of five key informants, 23 health professionals and 50 adolescents participated in a total of 38 semi-structured interviews and five discussion groups. RESULTS: Two intersectoral strategies to respond to adolescents' sexual and reproductive health needs were identified: (a) the "in-and-out" strategy, where health professionals provide health care mostly in health centres and carry out specific actions in schools and (b) the school-based strategy in which health professionals carry out continuous actions in schools as part of the curriculum. The second is perceived as responding better to adolescents' needs in sexual and reproductive health issues and in preventing adolescent pregnancy. DISCUSSION: The school-based strategy, with the constant presence of health professionals and lack of bureaucratic procedures, facilitates adolescents to access sexual and reproductive health care. This strategy enables sexual and reproductive health to be understood as an integral dimension of adolescents' lives, and it reinforces a holistic idea of health in which it is approached as a whole.

[Sexual and reproductive health in young men in Chile: results of a qualitative studySaúde sexual e reprodutiva de jovens do sexo masculino no Chile: resultados de um estudo qualitativo]. / Salud sexual y reproductiva de hombres jóvenes en Chile: resultados de un estudio cualitativo.

OBJECTIVE: To describe, based on the perceptions of adolescents and health service staff, the ways in which adolescent boys interact with sexual and reproductive health services, the changes perceived in this area over time, and the Espacios Amigables strategy ('Friendly Spaces' for adolescent health) to reach out to boys. METHODS: An ethnographic, qualitative study was conducted in Friendly Spaces for adolescent and young adult health in five municipalities belonging to Chile's Metropolitan Region. The research methods used were semi-structured interviews (N = 38), discussion groups (N = 5), and participant observation. RESULTS: A masculinities perspective was [TN: "un enfoque de masculinidades". Or simply: "Masculine perspectives were…"] felt to be missing in adolescent sexual and reproductive health care, which is perceived to be an area geared primarily toward females. Most adolescent boys perceive health services as distant and visit them only in case of emergency. Male attendance is low at sexual and reproductive health services in Friendly Spaces within primary health care centers. However, services outside these centers attract boys in larger numbers, for example, one that is exclusively devoted to providing adolescent health care and integrated services in schools. CONCLUSIONS: Greater provision of adolescent sexual and reproductive health services does not necessarily translate into increased male access. For such an increase to occur, it is important to engage boys in addressing issues that capture their interest, bring health services closer to them, strengthen intersectoral work, and incorporate a masculinities perspectives in their care.

OBJETIVO: Descrever, a partir das percepções dos jovens e do pessoal de saúde, as formas como os adolescentes do sexo masculino se relacionam com a atenção de saúde sexual e reprodutiva, as transformações percebidas neste âmbito e as estratégias para atenção de saúde do adolescente por espaços amigáveis para o alcance deste grupo. MÉTODOS: Foi realizado um estudo qualitativo etnográfico em espaços amigáveis para atenção de saúde de adolescentes e jovens em cinco municípios da região metropolitana do Chile. Foram empregados os métodos de entrevistas semiestruturadas (N = 38) e grupos de discussão (N = 5) e a técnica de observação participante. RESULTADOS: Foi verificada a falta de uma perspectiva de masculinidades na atenção de saúde sexual e reprodutiva para adolescentes, que se percebe como sendo voltada principalmente ao sexo feminino. A maioria dos adolescentes e jovens percebe os serviços de saúde como distantes e recorrem a eles sobretudo em situações de emergência. Foi observada pouca assistência ao sexo masculino nos serviços de saúde sexual e reprodutiva em espaços amigáveis situados em unidades de atenção primária à saúde. No entanto, a frequência dos jovens é maior nos espaços localizados fora destas unidades, como em um centro exclusivo de atenção de saúde do adolescente e serviços integrados em escolas. CONCLUSÕES: Uma maior oferta de serviços de saúde sexual e reprodutiva para adolescentes não implica necessariamente maior acesso do sexo masculino. Para isso, é importante atrair os jovens com assuntos do interesse deles, acercar os serviços de saúde de onde eles estão, reforçar o trabalho intersetorial e incorporar um enfoque de masculinidades à atenção.

Moving beyond disrespect and abuse: addressing the structural dimensions of obstetric violence.

During recent decades, a growing and preoccupying excess of medical interventions during childbirth, even in physiological and uncomplicated births, together with a concerning spread of abusive and disrespectful practices towards women during childbirth across the world, have been reported. Despite research and policy-making to address these problems, changing childbirth practices has proved to be difficult. We argue that the excessive rates of medical interventions and disrespect towards women during childbirth should be analysed as a consequence of structural violence, and that the concept of obstetric violence, as it is being used in Latin American childbirth activism and legal documents, might prove to be a useful tool for addressing structural violence in maternity care such as high intervention rates, non-consented care, disrespect and other abusive practices.

Joint response from Latin American, European Obstetric Violence Observatories and others organizations all over Europe to the Joint Position Statement on Substandard and Disrespectful Care in Labour - Because Words Matter.

The issue of obstetric violence is internationally acknowledged as a serious violation of human rights. First identified by the Committee of Experts of the Inter-American Belém do Pará Convention in 2012, it is recognized as a form of gender-based violence that infringes upon women's rights during childbirth. Nations such as Argentina, Mexico, Venezuela, and certain regions in Spain have implemented laws against it, highlighting its severity and the need for protective legislation. Major international organizations, including WHO and the Council of Europe, advocate for the elimination of disrespectful and abusive treatment in maternity care. In 2019, the UN Special Rapporteur on violence against women called on states to protect women's human rights in reproductive services by enforcing laws, prosecuting perpetrators, and providing compensation to victims. However, despite advances, there remains institutional and systemic resistance to recognizing obstetric violence, which undermines trust in healthcare and impacts women's quality of life. Addressing this violence is imperative, requiring education and training in women's human rights for all healthcare professionals. As part of the coalition of experts from various organizations (InterOVO), we respond to the publication by EAPM, EBCOG, and EMA: "Joint Position Statement: Substandard and Disrespectful Care in Labor - Because Words Matter." We are committed to preventing and mitigating obstetric violence and improving care for women and newborns.

Latin American Youths' Migration Journeys and Settlement in the Tarapacá Region in Chile: Implications for Sexual and Reproductive Health.

The sexual and reproductive health of young migrants has not been sufficiently addressed in mobility studies. In this article, we dwell on some aspects of this issue in the migration process of Latin American youth. We conducted a qualitative study in the region of Tarapacá, Chile, carrying out in-depth interviews with key informants, health staff and young migrants between 18 and 25 years old. The results show some motivations to migrate related to sexual and reproductive health: young pregnant women, LGBTQI+ and HIV-positive people seeking access to health care and social contexts of reduced gender discrimination. During the migration process, young people are exposed to various kinds of sexual violence, and in their settlement in Chile, to situations of racism, stigma and discrimination in society as a whole and in access to and during sexual and reproductive health care. Health care for young migrants is mainly focused on maternal care and reproductive issues, while sexual health as a whole is disregarded. We argue that sexual health must be addressed as a central dimension of the lived experiences of young migrants, and that the social, cultural and structural factors that undermine their sexual and reproductive health must be addressed in order to provide culturally competent health services.

Strengths and challenges of a school-based sexual and reproductive health program for adolescents in Chile.

BACKGROUND: Adolescent sexual and reproductive health services in Chile have been primarily provided through health centers. Although some school-based initiatives have been implemented, to date, these have not been assessed. This study aims to identify strengths and challenges of the affectivity and sexuality component of the school-based 3A Program, a health program which seeks to prevent risk behaviors and promote healthy lifestyle habits within public schools (addressing health topics which in Spanish begin with the letter 'A', hence '3A'), implemented in the municipality of Lo Prado, city of Santiago. METHODS: We carried out a qualitative study with a descriptive-interpretative approach in three schools. We conducted in-depth interviews with students, teachers, health professionals, and school principals (N = 44); and focus groups with students (N = 3), teachers and health personnel (N = 3). The interviews were analyzed using thematic analysis. RESULTS: Participants highlight the integrative approach to health and to sexual and reproductive health promoted in the 3A Program, which is enhanced by the collaboration of interdisciplinary health teams. Permanent and expedited student access to sexual and reproductive health care is achieved, and affectional bonds are developed between students and the Program's health staff. The Program assists female participants to imagine and form identities that are not inherently tied to motherhood. It also assists boys and LGBTQ+ adolescents in feeling included as relevant actors in sexual and reproductive health and decision making. The delivery of contraception in schools is highly valued. The most significant challenge identified is ensuring effective and ongoing collaboration between health staff and teachers. CONCLUSION: Participants value the effectivity and sexuality component of the 3A Program as an initiative to improve adolescents' access to sexual and reproductive health care. Our findings suggest that this Program could be replicated throughout the region and the country to improve the quality and accessibility of health services for adolescents.

The impact of COVID-19 on the provision of respectful maternity care: Findings from a global survey of health workers.

BACKGROUND: Significant adjustments to maternity care in response to the COVID-19 pandemic and the direct impacts of COVID-19 can compromise the quality of maternal and newborn care. AIM: To explore how the COVID-19 pandemic negatively affected frontline health workers' ability to provide respectful maternity care globally. METHODS: We conducted a global online survey of health workers to assess the provision of maternal and newborn healthcare during the COVID-19 pandemic. We collected qualitative data between July and December 2020 among a subset of respondents and conducted a qualitative content analysis to explore open-ended responses. FINDINGS: Health workers (n = 1127) from 71 countries participated; and 120 participants from 33 countries provided qualitative data. The COVID-19 pandemic negatively affected the provision of respectful maternity care in multiple ways. Six central themes were identified: less family involvement, reduced emotional and physical support for women, compromised standards of care, increased exposure to medically unjustified caesarean section, and staff overwhelmed by rapidly changing guidelines and enhanced infection prevention measures. Further, respectful care provided to women and newborns with suspected or confirmed COVID-19 infection was severely affected due to health workers' fear of getting infected and measures taken to minimise COVID-19 transmission. DISCUSSION: Multidimensional and contextually-adapted actions are urgently needed to mitigate the impacts of the COVID-19 pandemic on the provision and continued promotion of respectful maternity care globally in the long-term. CONCLUSIONS: The measures taken during the COVID-19 pandemic had the capacity to disrupt the provision of respectful maternity care and therefore the quality of maternity care.

Protecting Women's and Newborns' Rights in a Public Maternity Unit During the COVID-19 Outbreak: The Case of Dra. Eloísa Díaz - La Florida Hospital in Santiago, Chile.

The Maternity in Dra. Eloísa Díaz' hospital, located in the municipality of La Florida and city of Santiago, Chile, opened its doors in 2014, and has integrated a humanistic model of care called the "Safe Model of Personalized Childbirth" since 2016. With around 3,000 births per year, it has been recognized as an example of excellence in maternity care in the country. The COVID-19 outbreak presented a big challenge to this Maternity: to maintain its quality of care standards despite the health crisis. This article presents the Maternity's responses to the pandemic from March to July 2020, describing the strategies that were deployed and the obstetric outcomes achieved. Semi-structured interviews with midwives and OB-GYNs, and a retrospective review of the childbirth standards of care and outcomes of the 55 women who tested positive for SARS-CoV-2, were carried out. The results show how the Maternity's staff responded in order to avoid a significant negative impact on the rights of women and newborns. Protocols to reestablish the companion during labor and childbirth and skin-to-skin contact, which were suspended for almost three weeks at the beginning of the outbreak, and the creation of an Instagram account to communicate with the external community were some of the measures taken. After some initial weeks of adjustment, the standards of care for all women, included for those diagnosed with COVID-19, were reestablished almost to pre-pandemic levels. This case shows that quality of care can be maintained and the rights of women and newborns can be respected during health crisis such as the COVID-19 pandemic.

Preference for caesarean attitudes toward birth in a Chilean sample of young adults.

BACKGROUND: Little empirical research exists about what motivates birth mode preferences, and even less about this topic in Latin America, where obstetric interventions and caesareans are some of the highest worldwide. AIM: To identify factors associated with caesarean preference among Chilean men and women who plan to have children and to inform childbirth education and informed consent procedures. METHODS: An online cross-sectional survey measuring attitudes toward birth was administered to graduate students at a large public university in Chile. Eligible students were under the age of 40 and had no children but intended to have children. Logistic regression modelling was used to determine which sociodemographic factors, knowledge and beliefs were associated with caesarean preference. FINDINGS: Among eligible students, 730 responded and 664 provided complete answers to the variables of interest. Respondents had a mean age of 28.8; 38% were male and 62% female. Positive attitude toward technological intervention (Odds Ratio 7.4, 95% Confidence Interval 3.9-14.0), high risk perception of vaginal birth (Odds Ratio 1.8, 95% Confidence Interval 1.1-2.8), family history of caesarean (Odds Ratio 1.9, 95% Confidence Interval 1.0-3.8) and high fear of birth (Odds Ratio 3.7, 95% Confidence Interval 2.0-6.8) were associated with caesarean preference. DISCUSSION: Preference for caesarean birth was highly associated with positive attitudes toward technological intervention and may be related to a lack of knowledge about the realities of caesarean and vaginal birth. CONCLUSIONS: Patient-centered education on the relative benefits and risks of birth modes has the potential to influence preferences toward vaginal birth.

A Survey of University Students' Preferences for Midwifery Care and Community Birth Options in 8 High-Income Countries.

INTRODUCTION: Midwifery care is associated with positive birth outcomes, access to community birth options, and judicious use of interventions. The aim of this study was to characterize and compare maternity care preferences of university students across a range of maternity care systems and to explore whether preferences align with evidence-based recommendations and options available. METHODS: A cross-sectional, web-based survey was completed in 2014 and 2015 by a convenience sample of university students in 8 high-income countries across 4 continents (N = 4569). In addition to describing preferences for midwifery care and community birth options across countries, this study examined sociodemographic characteristics, psychological factors, knowledge about pregnancy and birth, and sources of information that shaped students' attitudes toward birth in relation to preferences for midwifery care and community birth options. RESULTS: Approximately half of the student respondents (48.2%) preferred midwifery-led care for a healthy pregnancy; 9.5% would choose to give birth in a birthing center, and 4.5% preferred a home birth. Preference for midwifery care varied from 10.3% among women in the United States to 78.6% among women in the United Kingdom. Preferences for home birth varied from 0.3% among US women to 18.3% among Canadian women. Women, health science students, those with low childbirth fear, those who learned about pregnancy and birth from friends (compared with other sources, eg, the media), and those who responded from Europe were significantly more likely to prefer midwifery care and community birth. High confidence in knowledge of pregnancy and birth was linked to significantly higher odds of community birth preferences and midwifery care preferences. DISCUSSION: It would be beneficial to integrate childbirth education into high school curricula to promote knowledge of midwifery care, pregnancy, and childbirth and to reduce fear among prospective parents. Community birth options need to be expanded to meet demand among the next generation of maternity service users.

A cross-country survey of attitudes toward childbirth technologies and interventions among university students.

PROBLEM & AIM: Cultural beliefs that equate birth technology with progress, safety and convenience contribute to widespread acceptance of childbirth technology and interventions. Little is known about attitudes towards childbirth technology and interventions among the next generation of maternity care users and whether attitudes vary by country, age, gender, childbirth fear, and other factors. METHODS: Data were collected via online survey in eight countries. Students who had never had children, and who planned to have at least one child were eligible to participate. FINDINGS: The majority of participants (n=4569) were women (79.3%), and the median age was 22 years. More than half of students agreed that birth technology makes birth easier (55.8%), protects babies from harm (49.1%) and that women have a right to choose a medically non-indicated cesarean (50.8%). Respondents who had greater acceptance of childbirth technology and interventions were from countries with higher national caesarean birth rates, reported higher levels of childbirth fear, and were more likely to report that visual media or school-based education shaped their attitudes toward birth. Positive attitudes toward childbirth technology and interventions were also associated with less confidence in knowledge of birth, and more common among younger and male respondents. DISCUSSION/CONCLUSION: Educational strategies to teach university students about pregnancy and birth in ways that does not frighten them and promotes critical reflection about childbirth technology are needed. This is especially true in countries with high rates of interventions that reciprocally shape culture norms, attitudes, and expectations.

Effects of prior hypoglycemia and hyperglycemia on cognition in children with type 1 diabetes mellitus.

OBJECTIVE: Despite the general consensus that youth with type 1 diabetes mellitus (T1DM) can experience modest cognitive impairment, debate continues over the role of severe hypoglycemia (Hypo) and/or hyperglycemia (Hyper) in producing such impairment. Our aim was to determine how Hypo and Hyper experienced during brain development predict patterns of subsequent cognitive performance in youth with T1DM. METHODS: We tested youth aged 5-16 yr (T1DM, n = 117; non-diabetic sibling controls, n = 58) on cognitive tasks (verbal and spatial intelligence, verbal and spatial memory, and processing speed). T1DM participants were categorized as having experienced 0, 1-2, or 3 or more (3+) Hypo episodes, as having their first Hypo episode before or after 5 yr of age and as having early (before age 5) or late (after age 5) diabetes onset. Hyper exposure was estimated with median hemoglobin A1c, adjusted for diabetes duration for each subject. RESULTS: The group with T1DM had lower estimated verbal intelligence than sibling controls. Within the T1DM group, verbal intelligence was reduced with increased exposure to Hyper, not to Hypo. In contrast, spatial intelligence and delayed recall were reduced only with repeated Hypo, particularly when Hypo episodes occurred before the age of 5 yr. Age of onset did not explain these results. CONCLUSIONS: Hypo and Hyper have qualitatively different effects on cognitive function in T1DM that depend in part on the timing of exposure during development, independent of onset age. This information extends the known benefits of avoiding both Hypo and chronic Hyper during childhood to include preservation of specific cognitive skills.

Randomized, controlled trial of Behavioral Family Systems Therapy for Diabetes: maintenance and generalization of effects on parent-adolescent communication.

We report a randomized trial of a revised Behavioral Family Systems Therapy for Diabetes (BFST-D) intervention. Families of 104 adolescents with diabetes were randomized to standard care (SC) or to 6 months of an educational support group (ES) or BFST-D. Family communication and problem-solving skills were assessed at 0, 6, 12, and 18 months by independent rating of videotaped family problem-solving discussions. BFST-D improved individual communication of adolescents and mothers, but not fathers. BFST-D significantly improved quality of family interaction compared to SC (10 of 12 comparisons) and ES (6 of 12 comparisons). Changes in family communication were differentially associated with changes in glycemic control, adherence, and family conflict. BFST-D improved family communication and problem solving relative to SC and modestly relative to ES.

[Sexual and reproductive health of adolescents in Chile: the role of sexual education]. / Salud sexual y reproductiva de adolescentes en Chile: el rol de la educación sexual.

OBJECTIVE: To explore the perceptions of adolescents regarding sex education in the Metropolitan Region of Chile, and the role of the health and education sectors in this matter. METHODS: Qualitative ethnographic study, whose fieldwork was carried out in five municipalities of the Metropolitan Region of Chile. In each municipality a Friendly Space for adolescent healthcare was studied. Semi-structured interviews (N=38), discussion groups (N=5) and participant observation techniques were used. RESULTS: A negative perception among adolescents was identified regarding the sex education they receive.They express that there is a need for information on sexual and reproductive health, which addresses in depth the biological, emotional and affective dimensions of sexuality, overcoming conservative and risk-based approaches to sexuality. Innovative health strategies focused on schools were identified, where the health and education sectors work collaboratively on sex education. DISCUSSION: When the health and education sectors work in a collaborative and coordinated manner, a better response to the needs of adolescents can be achieved in terms of information and sex education. Although this intersectoral work constitutes a progress, the challenge of incorporating the voices of adolescents and their communities remains to be addressed to plan sex education programs and policies based on their life experiences, thus advancing towards sexual and reproductive rights for this group.

OBJETIVOS: Indagar sobre las percepciones de adolescentes en torno a la educación sexual en la Región Metropolitana de Chile y el rol de los sectores de salud y educación en esta materia. MÉTODOS: Estudio cualitativo etnográfico, cuyo trabajo de campo se llevó a cabo en cinco comunas de la Región Metropolitana de Chile, en cada una de las cuales se abordó un Espacio Amigable para atención adolescente. Se utilizaron las técnicas de entrevistas semi-estructuradas (N=38), grupos de discusión (N=5) y observación participante. RESULTADOS: Se identificó una percepción negativa por parte de adolescentes respecto a la educación sexual que reciben. Sostienen la necesidad de información en salud sexual y reproductiva que cubra en profundidad las dimensiones tanto biológicas como emocionales y afectivas de la sexualidad, superando enfoques conservadores y de riesgo en torno a la sexualidad. Se identificaron estrategias innovadoras en salud, centradas en las escuelas, donde los sectores de salud y educación trabajan de manera colaborativa en materia de educación sexual. DISCUSIÓN: Cuando los sectores de salud y educación trabajan de manera colaborativa y coordinada, se da una mejor respuesta a las necesidades de adolescentes en materia de información y educación sexual. Si bien este trabajo intersectorial constituye un avance, está pendiente el desafío de incorporar las voces de los adolescentes y sus comunidades, con el fin de planificar programas y políticas de educación sexual que se basen en sus experiencias vitales, avanzando con ello hacia los derechos sexuales y reproductivos de este grupo.

Frequency and timing of severe hypoglycemia affects spatial memory in children with type 1 diabetes.

OBJECTIVE: Repeated severe hypoglycemia has been reported to reduce long-term spatial memory in children with type 1 diabetes. Early exposure to hypoglycemia may be more damaging to cognitive function than later exposure. Our goal was to determine whether the age at which severe hypoglycemia occurs modulates the impact of severe hypoglycemia frequency on long-term spatial memory. RESEARCH DESIGN AND METHODS: We combined data from three independent studies to obtain a sample of children aged 6-18 years with type 1 diabetes (n = 103) and nondiabetic control subjects (n = 60). Each study evaluated previous severe hypoglycemia and tested short (5 s)- and long (60 s)-delay spatial memory with the spatial delayed response task. Type 1 diabetic participants were categorized as having zero, one to two, or three or more severe hypoglycemic episodes and as having their first severe hypoglycemic episode before or after 5 years of age. Information on chronic hyperglycemia (HbA1c values) was also collected. RESULTS: We found that repeated severe hypoglycemia (more than three episodes) reduced long-delay spatial delayed response performance, particularly when severe hypoglycemic episodes began before the age of 5 years. Age of type 1 diabetes onset and estimates of chronic hyperglycemia did not influence performance. CONCLUSIONS: High frequency of and early exposure to severe hypoglycemia during development negatively affects spatial long-term memory performance.

Self-management competence as a predictor of outcomes of intensive therapy or usual care in youth with type 1 diabetes.

OBJECTIVE: This article evaluates prediction of HbA(1c) during an 18-month randomized trial of intensive therapy (IT) versus usual care (UC) for type 1 diabetes in 142 youth. RESEARCH DESIGN AND METHODS: Patients received a composite score for self-management competence (SMC) that combined standardized scores on baseline measures of diabetes knowledge, treatment adherence, and quality of health care interactions. They were categorized by tertiles split into low, moderate, and high SMC levels. RESULTS: IT yielded very similar mean HbA(1c) levels in all three SMC groups. However, in UC patients, HbA(1c) increased markedly for low-SMC youth but not for moderate- and high-SMC youth during the trial. Compared with the mean HbA(1c) of their UC counterparts, low-SMC patients realized greater glycemic benefit from IT than did the moderate- or high-SMC youth. Baseline SMC was more strongly correlated with HbA(1c) for UC than IT. CONCLUSIONS: All three SMC groups realized similar glycemic benefits from IT. The mean HbA(1c) levels of low-SMC patients in the UC group increased markedly over 18 months, whereas HbA(1c) levels of low-SMC patients in the IT group did not differ significantly from that of moderate- and high-SMC patients. Relative to their UC counterparts, low-SMC patients derived greater glycemic benefit from IT than did moderate- or high-SMC youth. SMC may be more critical to the success of UC than IT. Perhaps more importantly, patients should not be denied access to IT on the basis of limited competence in diabetes self-management.