1.
W V Med J
; 109(2): 6-9, 2013.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23600098
RESUMEN
Myeloid neoplasm with eosinophilia and abnormalities of Alpha type platelet derived growth factor receptor (PDGFRA) is a type of hypereosinophilic syndrome characterized by multiorgan damage due to eosinophilia. Its association with thrombotic thrombocytopenic purpura (TTP) has rarely been reported. We describe here a case report of a female in whom TTP presented as one of the earlier manifestations of myeloproliferative HES with rearrangement of PDGFRA. Our patient was found to have a normal ADAMTS-13 level which is not commonly seen with TTP. This case illustrates the importance of recognizing the atypical presentations of HES which may be difficult to recognize.
Asunto(s)
Síndrome Hipereosinofílico/diagnóstico , Trastornos Mieloproliferativos/diagnóstico , Proteínas de Fusión Oncogénica/genética , Púrpura Trombocitopénica Trombótica/diagnóstico , Receptor alfa de Factor de Crecimiento Derivado de Plaquetas/genética , Factores de Escisión y Poliadenilación de ARNm/genética , Adulto , Femenino , Reordenamiento Génico , Humanos , Síndrome Hipereosinofílico/genética , Trastornos Mieloproliferativos/genética
2.
Rapid resolution of GVHD after orthotopic liver transplantation in a patient treated with alefacept.
Blood
; 113(21): 5365-6, 2009 May 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19470441