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1.
Measuring Serum Vedolizumab and Vedolizumab Antibodies: Comparison of Commercial Assays with the Vedolizumab Clinical Development Assay.
Ther Drug Monit
; 45(2): 236-244, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36788448
2.
The safety, tolerability and pharmacokinetics of niraparib in Japanese patients with solid tumours: results of a phase I dose-escalation study.
Jpn J Clin Oncol
; 51(5): 693-699, 2021 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33621324
3.
Phase 1/2 study of orteronel (TAK-700), an investigational 17,20-lyase inhibitor, with docetaxel-prednisone in metastatic castration-resistant prostate cancer.
Invest New Drugs
; 33(2): 397-408, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25556680
4.
Assessment of cytochrome P450-mediated drug-drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinetic modeling and simulation.
Biopharm Drug Dispos
; 35(9): 543-52, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25264242
5.
Risk-Based Pharmacokinetic and Drug-Drug Interaction Characterization of Antibody-Drug Conjugates in Oncology Clinical Development: An International Consortium for Innovation and Quality in Pharmaceutical Development Perspective.
Clin Pharmacol Ther
; 112(4): 754-769, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34657311
6.
Assessment of Vedolizumab Disease-Drug-Drug Interaction Potential in Patients With Inflammatory Bowel Diseases.
Clin Pharmacol Drug Dev
; 10(7): 734-747, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33331142
7.
Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer.
J Gynecol Oncol
; 32(2): e21, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33470063
8.
Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer.
J Gynecol Oncol
; 32(2): e16, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33327047
9.
Population Pharmacokinetics of Brentuximab Vedotin in Adult and Pediatric Patients With Relapsed/Refractory Hematologic Malignancies: Model-Informed Hypothesis Generation for Pediatric Dosing Regimens.
J Clin Pharmacol
; 60(12): 1585-1597, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32596842
10.
Phase II study of gemcitabine monotherapy as a salvage treatment for Japanese metastatic breast cancer patients after anthracycline and taxane treatment.
Jpn J Clin Oncol
; 39(11): 699-706, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19776022
11.
Population Pharmacokinetic Modeling and Exposure-Response Assessment for the Antibody-Drug Conjugate Brentuximab Vedotin in Hodgkin's Lymphoma in the Phase III ECHELON-1 Study.
Clin Pharmacol Ther
; 106(6): 1268-1279, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31152605
12.
Population PK and Exposure-Response Relationships for the Antibody-Drug Conjugate Brentuximab Vedotin in CTCL Patients in the Phase III ALCANZA Study.
Clin Pharmacol Ther
; 104(5): 989-999, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29377077
13.
Brentuximab vedotin for paediatric relapsed or refractory Hodgkin's lymphoma and anaplastic large-cell lymphoma: a multicentre, open-label, phase 1/2 study.
Lancet Haematol
; 5(10): e450-e461, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30290902
14.
Comparison of standard (self-directed) versus intensive patient training for the human insulin inhalation powder (HIIP) delivery system in patients with type 2 diabetes: efficacy, safety, and training measures.
Diabetes Technol Ther
; 9(1): 80-8, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17316102
15.
Absorption, Distribution, and Excretion of the Investigational Agent Orteronel (TAK-700) in Healthy Male Subjects: A Phase 1, Open-Label, Single-Dose Study.
Clin Pharmacol Drug Dev
; 5(3): 180-7, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27163496
16.
A Phase 1, Randomized, Single-Dose Crossover Pharmacokinetic Study to Investigate the Effect of Food Intake on Absorption of Orteronel (TAK-700) in Healthy Male Subjects.
Clin Pharmacol Drug Dev
; 5(3): 188-95, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27163497
17.
A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer.
Lung Cancer
; 49(3): 401-12, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15923057
18.
A phase IB study of the pharmacokinetics of gemcitabine and pemetrexed, when administered in rapid sequence to patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 55(6): 522-30, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15754203
19.
Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride.
Neuropsychopharmacology
; 27(2): 248-59, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12093598
20.
Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies.
J Clin Endocrinol Metab
; 99(8): E1445-53, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24762108