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Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Neurobiol Pain
; 14: 100136, 2023.
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| MEDLINE | ID: mdl-38099276
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