A Simple Wireless Sensor Node System for Electricity Monitoring Applications: Design, Integration, and Testing with Different Piezoelectric Energy Harvesters.

Real time electricity monitoring is critical to enable intelligent and customized energy management for users in residential, educational, and commercial buildings. This paper presents the design, integration, and testing of a simple, self-contained, low-power, non-invasive system at low cost applicable for such purpose. The system is powered by piezoelectric energy harvesters (EHs) based on PZT and includes a microcontroller unit (MCU) and a central hub. Real-time information regarding the electricity consumption is measured and communicated by the system, which ultimately offers a dependable and promising solution as a wireless sensor node. The dynamic power management ensures the system to work with different types of PZT EHs at a wide range of input power. Thus, the system is robust against fluctuation of the current in the electricity grid and requires minimum adjustment if EH unit requires exchange or upgrade. Experimental results demonstrate that this unit is in a position to read and transmit 60 Hz alternating current (AC) sensor signals with a high accuracy no less than 91.4%. The system is able to achieve an operation duty cycle from <1 min up to 18 min when the current in an electric wire varies from 7.6 A to 30 A, depending on the characteristics of different EHs and intensity of current being monitored.

Circular RNAs in colorectal cancer: Possible roles in regulation of cancer cells.

Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world and the fourth principal cause of cancer deaths worldwide. Currently, there is a lack of low cost and noninvasive screening tests for CRC, becoming a serious health problem. In this context, a potential biomarker for the early detection of CRC has recently gained attention. Circular RNAs (circRNA), a re-discovered, abundant RNA specie, is a type of noncoding covalent closed RNAs formed from both exonic and intronic sequences. These circular molecules are widely expressed in cells, exceeding the abundance of the traditional linear mRNA transcript. They can regulate gene expression, acting as real sponges for miRNAs and also regulate alternative splicing or act as transcriptional factors and inclusive encoding for proteins. However, little is known about circRNA and its relationship with CRC. In this review, we focus on the biogenesis, function and role of these circRNAs in relation to CRC, including their potential as a new biomarker.