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1.
Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis.
ACS Med Chem Lett
; 10(8): 1134-1139, 2019 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31417666
2.
Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.
J Med Chem
; 56(5): 1799-810, 2013 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23398373
3.
Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors.
J Med Chem
; 54(7): 2341-50, 2011 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21391610
4.
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors.
J Biol Chem
; 279(18): 18727-32, 2004 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-14766749
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