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1.
Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice.
Mol Pharm
; 17(1): 316-326, 2020 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31790256
2.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Mol Pharm
; 16(3): 1282-1293, 2019 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30694684
3.
Effect of Rifampicin on the Distribution of [11C]Erlotinib to the Liver, a Translational PET Study in Humans and in Mice.
Mol Pharm
; 15(10): 4589-4598, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30180590
4.
Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography.
Drug Metab Dispos
; 45(10): 1093-1100, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28790147
5.
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Bioorg Med Chem
; 24(21): 5326-5339, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27614920
6.
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
Mol Pharm
; 12(9): 3214-25, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26202880
7.
Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice.
Pharmaceutics
; 13(8)2021 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34452247
8.
Influence of ABC transporters on the excretion of ciprofloxacin assessed with PET imaging in mice.
Eur J Pharm Sci
; 163: 105854, 2021 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33865975
9.
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice.
Mol Imaging Biol
; 21(2): 306-316, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29942989
10.
Reproducibility and Comparability of Preclinical PET Imaging Data: A Multicenter Small-Animal PET Study.
J Nucl Med
; 60(10): 1483-1491, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30850496
11.
Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice.
Eur J Pharm Sci
; 115: 212-222, 2018 Mar 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29360507
12.
Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.
Clin Pharmacol Ther
; 104(1): 139-147, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28940241
13.
A Prediction Method for P-glycoprotein-Mediated Drug-Drug Interactions at the Human Blood-Brain Barrier From Blood Concentration-Time Profiles, Validated With PET Data.
J Pharm Sci
; 106(9): 2780-2786, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28385544
14.
[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.
Nucl Med Biol
; 52: 7-15, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28575795
15.
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood-Brain Barrier: A PET Study on Nonhuman Primates.
J Nucl Med
; 58(1): 117-122, 2017 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-27493269
16.
[(18)F]FDG is not transported by P-glycoprotein and breast cancer resistance protein at the rodent blood-brain barrier.
Nucl Med Biol
; 42(7): 585-9, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25823393
17.
Breast Cancer Resistance Protein and P-Glycoprotein Influence In Vivo Disposition of 11C-Erlotinib.
J Nucl Med
; 56(12): 1930-6, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26359257
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