1.
J Am Chem Soc
; 140(6): 2007-2011, 2018 02 14.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29376366
RESUMEN
We report a method for the highly enantioselective CuH-catalyzed allylation of ketones that employs terminal allenes as allylmetal surrogates. Ketones and allenes bearing diverse and sensitive functional groups are efficiently coupled with high stereoselectivity and exclusive branched regioselectivity. In stoichiometric experiments, each elementary step of the proposed hydrocupration-addition-metathesis mechanism can be followed by NMR spectroscopy.
Asunto(s)
Alcadienos/química , Compuestos Alílicos/química , Cobre/química , Cetonas/química , Catálisis , Espectroscopía de Resonancia Magnética , Modelos Moleculares , Oxidación-Reducción , Estereoisomerismo
2.
Correction to "A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes".
J Am Chem Soc
; 140(19): 6184, 2018 05 16.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29737849