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1.
[A proposal to improve operating room nursing personnel adherence to mandated X-ray protection measures].
Hu Li Za Zhi
; 57(2): 79-86, 2010 Apr.
Artículo
en Zh
| MEDLINE | ID: mdl-20401870
2.
5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(2): 451-8, 2009 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19054673
3.
5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(21): 6047-52, 2009 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19796938
4.
Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(22): 6404-12, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19818610
5.
Omega-3 polyunsaturated fatty acids suppress metastatic features of human cholangiocarcinoma cells by suppressing twist.
J Nutr Biochem
; 74: 108245, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31678746
6.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents.
Bioorg Med Chem Lett
; 18(4): 1419-24, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18226901
7.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine.
Bioorg Med Chem Lett
; 18(4): 1413-8, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18242088
8.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents.
Bioorg Med Chem Lett
; 18(20): 5635-9, 2008 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18796353
9.
Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(18): 5002-5, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18722768
10.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties.
Bioorg Med Chem Lett
; 18(11): 3421-6, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18442904
11.
Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(12): 3616-21, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18487044
12.
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 18(14): 4181-5, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18554907
13.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments.
Bioorg Med Chem Lett
; 18(11): 3446-55, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18457949
14.
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(16): 4628-32, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18662878
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