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1.

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.

Soldner, Frank; Laganière, Josée; Cheng, Albert W; Hockemeyer, Dirk; Gao, Qing; Alagappan, Raaji; Khurana, Vikram; Golbe, Lawrence I; Myers, Richard H; Lindquist, Susan; Zhang, Lei; Guschin, Dmitry; Fong, Lauren K; Vu, B Joseph; Meng, Xiangdong; Urnov, Fyodor D; Rebar, Edward J; Gregory, Philip D; Zhang, H Steve; Jaenisch, Rudolf.

Cell ; 146(2): 318-31, 2011 Jul 22.

Artículo en Inglés | MEDLINE | ID: mdl-21757228

2.

Distinct factors control histone variant H3.3 localization at specific genomic regions.

Goldberg, Aaron D; Banaszynski, Laura A; Noh, Kyung-Min; Lewis, Peter W; Elsaesser, Simon J; Stadler, Sonja; Dewell, Scott; Law, Martin; Guo, Xingyi; Li, Xuan; Wen, Duancheng; Chapgier, Ariane; DeKelver, Russell C; Miller, Jeffrey C; Lee, Ya-Li; Boydston, Elizabeth A; Holmes, Michael C; Gregory, Philip D; Greally, John M; Rafii, Shahin; Yang, Chingwen; Scambler, Peter J; Garrick, David; Gibbons, Richard J; Higgs, Douglas R; Cristea, Ileana M; Urnov, Fyodor D; Zheng, Deyou; Allis, C David.

Cell ; 140(5): 678-91, 2010 Mar 05.

Artículo en Inglés | MEDLINE | ID: mdl-20211137

3.

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Sexton, Alec N; Regalado, Samuel G; Lai, Christine S; Cost, Gregory J; O'Neil, Colleen M; Urnov, Fyodor D; Gregory, Philip D; Jaenisch, Rudolf; Collins, Kathleen; Hockemeyer, Dirk.

Genes Dev ; 28(17): 1885-99, 2014 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-25128433

4.

Hijack of CRISPR defences by selfish genes holds clinical promise.

Urnov, Fyodor D.

Nature ; 571(7764): 180-181, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31285598

5.

Translating dosage compensation to trisomy 21.

Jiang, Jun; Jing, Yuanchun; Cost, Gregory J; Chiang, Jen-Chieh; Kolpa, Heather J; Cotton, Allison M; Carone, Dawn M; Carone, Benjamin R; Shivak, David A; Guschin, Dmitry Y; Pearl, Jocelynn R; Rebar, Edward J; Byron, Meg; Gregory, Philip D; Brown, Carolyn J; Urnov, Fyodor D; Hall, Lisa L; Lawrence, Jeanne B.

Nature ; 500(7462): 296-300, 2013 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-23863942

6.

Prime Time for Genome Editing?

Urnov, Fyodor D.

N Engl J Med ; 382(5): 481-484, 2020 01 30.

Artículo en Inglés | MEDLINE | ID: mdl-31995698

7.

Improved specificity of TALE-based genome editing using an expanded RVD repertoire.

Miller, Jeffrey C; Zhang, Lei; Xia, Danny F; Campo, John J; Ankoudinova, Irina V; Guschin, Dmitry Y; Babiarz, Joshua E; Meng, Xiangdong; Hinkley, Sarah J; Lam, Stephen C; Paschon, David E; Vincent, Anna I; Dulay, Gladys P; Barlow, Kyle A; Shivak, David A; Leung, Elo; Kim, Jinwon D; Amora, Rainier; Urnov, Fyodor D; Gregory, Philip D; Rebar, Edward J.

Nat Methods ; 12(5): 465-71, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25799440

8.

Functional footprinting of regulatory DNA.

Vierstra, Jeff; Reik, Andreas; Chang, Kai-Hsin; Stehling-Sun, Sandra; Zhou, Yuanyue; Hinkley, Sarah J; Paschon, David E; Zhang, Lei; Psatha, Nikoletta; Bendana, Yuri R; O'Neil, Colleen M; Song, Alexander H; Mich, Andrea K; Liu, Pei-Qi; Lee, Gary; Bauer, Daniel E; Holmes, Michael C; Orkin, Stuart H; Papayannopoulou, Thalia; Stamatoyannopoulos, George; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D; Stamatoyannopoulos, John A.

Nat Methods ; 12(10): 927-30, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26322838

9.

Imagine CRISPR cures.

Urnov, Fyodor D.

Mol Ther ; 29(11): 3103-3106, 2021 11 03.

Artículo en Inglés | MEDLINE | ID: mdl-34710352

10.

Genome editing with engineered zinc finger nucleases.

Urnov, Fyodor D; Rebar, Edward J; Holmes, Michael C; Zhang, H Steve; Gregory, Philip D.

Nat Rev Genet ; 11(9): 636-46, 2010 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-20717154

11.

Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing.

Kiem, Hans-Peter; Gaudelli, Nicole N; Urnov, Fyodor D; Frederickson, Robert M; Herzog, Roland W.

Mol Ther ; 28(8): 1743, 2020 08 05.

Artículo en Inglés | MEDLINE | ID: mdl-32679031

12.

Cas9 in action: no more known unknowns?

Urnov, Fyodor D.

Nat Methods ; 14(6): 563-564, 2017 05 30.

Artículo en Inglés | MEDLINE | ID: mdl-28557979

13.

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

Straimer, Judith; Lee, Marcus C S; Lee, Andrew H; Zeitler, Bryan; Williams, April E; Pearl, Jocelynn R; Zhang, Lei; Rebar, Edward J; Gregory, Philip D; Llinás, Manuel; Urnov, Fyodor D; Fidock, David A.

Nat Methods ; 9(10): 993-8, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22922501

14.

Biological techniques: Edit the genome to understand it.

Urnov, Fyodor D.

Nature ; 513(7516): 40-1, 2014 Sep 04.

Artículo en Inglés | MEDLINE | ID: mdl-25141180

15.

Precise genome modification in the crop species Zea mays using zinc-finger nucleases.

Shukla, Vipula K; Doyon, Yannick; Miller, Jeffrey C; DeKelver, Russell C; Moehle, Erica A; Worden, Sarah E; Mitchell, Jon C; Arnold, Nicole L; Gopalan, Sunita; Meng, Xiangdong; Choi, Vivian M; Rock, Jeremy M; Wu, Ying-Ying; Katibah, George E; Zhifang, Gao; McCaskill, David; Simpson, Matthew A; Blakeslee, Beth; Greenwalt, Scott A; Butler, Holly J; Hinkley, Sarah J; Zhang, Lei; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D.

Nature ; 459(7245): 437-41, 2009 May 21.

Artículo en Inglés | MEDLINE | ID: mdl-19404259

16.

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Sanders, Laurie H; Laganière, Josée; Cooper, Oliver; Mak, Sally K; Vu, B Joseph; Huang, Y Anne; Paschon, David E; Vangipuram, Malini; Sundararajan, Ramya; Urnov, Fyodor D; Langston, J William; Gregory, Philip D; Zhang, H Steve; Greenamyre, J Timothy; Isacson, Ole; Schüle, Birgitt.

Neurobiol Dis ; 62: 381-6, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24148854

17.

Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila.

Foulk, Michael S; Waggener, John M; Johnson, Janell M; Yamamoto, Yutaka; Liew, Gerald M; Urnov, Fyodor D; Young, Yuki; Lee, Genee; Smith, Heidi S; Gerbi, Susan A.

Chromosoma ; 122(1-2): 103-19, 2013 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-23321980

18.

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.

Doyon, Yannick; Vo, Thuy D; Mendel, Matthew C; Greenberg, Shon G; Wang, Jianbin; Xia, Danny F; Miller, Jeffrey C; Urnov, Fyodor D; Gregory, Philip D; Holmes, Michael C.

Nat Methods ; 8(1): 74-9, 2011 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21131970

19.

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

Wang, Yongming; Zhang, Wendy Y; Hu, Shijun; Lan, Feng; Lee, Andrew S; Huber, Bruno; Lisowski, Leszek; Liang, Ping; Huang, Mei; de Almeida, Patricia E; Won, Jong H; Sun, Ning; Robbins, Robert C; Kay, Mark A; Urnov, Fyodor D; Wu, Joseph C.

Circ Res ; 111(12): 1494-503, 2012 Dec 07.

Artículo en Inglés | MEDLINE | ID: mdl-22967807

20.

Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases.

Young, John J; Cherone, Jennifer M; Doyon, Yannick; Ankoudinova, Irina; Faraji, Farhoud M; Lee, Andrew H; Ngo, Catherine; Guschin, Dmitry Y; Paschon, David E; Miller, Jeffrey C; Zhang, Lei; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D; Harland, Richard M; Zeitler, Bryan.

Proc Natl Acad Sci U S A ; 108(17): 7052-7, 2011 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-21471457

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Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.

Distinct factors control histone variant H3.3 localization at specific genomic regions.

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Hijack of CRISPR defences by selfish genes holds clinical promise.

Translating dosage compensation to trisomy 21.

Prime Time for Genome Editing?

Improved specificity of TALE-based genome editing using an expanded RVD repertoire.

Functional footprinting of regulatory DNA.

Imagine CRISPR cures.

Genome editing with engineered zinc finger nucleases.

Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing.

Cas9 in action: no more known unknowns?

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

Biological techniques: Edit the genome to understand it.

Precise genome modification in the crop species Zea mays using zinc-finger nucleases.

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila.

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases.