1.
Kidney Int
; 88(3): 444-6, 2015 Sep.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26323072
RESUMEN
The analyses of indirect T-cell responses in patients with antibody-mediated renal transplant injury by Shiu et al. emphasize the complex contribution of B cells in alloimmunity. The data suggest at least three distinct but potentially overlapping consequences of T cell-B cell interactions: antigen presentation by B cells, alloantibody production, and immune regulation. These multifaceted functions of B cells should be taken into consideration in developing diagnostic tools and therapeutic strategies.