[Ovarian tumor and Peutz-Jeghers syndrome. A case report]. / Tumeurs ovariennes et syndrome de Peutz-Jeghers. A propos d'un cas.

A case of Peutz-Jeghers syndrome associated with ovarian mucinous cystadenoma and ovarian sex cord tumor with annular tubules is presented. The sec cord tumor with annular tubules was described in 1970 by Scully, who recognized its striking association with the Peutz-Jeghers syndrome. This tumor is an almost constant finding in patients' ovaries with this disorder. Three cases of ovarian mucinous cystadenoma and sex cord tumor with annular tubules associated with Peutz-Jeghers syndrome were found in the literature. Our observation confirms that gynecologic abnormalities are an important manifestation of the syndrome and require careful surveillance.

Wastewater sludge convective drying: influence of sludge origin.

This paper deals with thermal drying of wastewater sludges, whose management will become crucial in the forthcoming years. Sludges collected after mechanical dewatering in 5 different WWTPs are submitted to the same convective drying treatment in order to try finding some relations between the drying behaviours, the type of effluent and wastewater treatments. Results show dearly sludge drying remains a particularly complex operation because sludges may exhibit very different behaviours, both from kinetic and texture points of view. Initial moisture content and global composition are not sufficient to explain the different observed behaviours. It is too early to claim one or another type of water treatment has an influence on the drying behaviour. However, the drying rates can be classified in the inverse order of the organic content. Moreover for sludges at the same siccities, the harder the material (rheological properties), the higher the drying rate. Final textural properties can be related to the rheological properties and the internal diffusion limitations lowering the drying intensity.

[Nitrates in drinking water and cancer]. / Nitrates de l'eau de boisson et cancer.

Nitrates originating from food and particularly from water are supposedly precursors of carcinogenic N-nitroso compound (NOC) formed within the organism. According to Correa and al. these transformations could be a consequence of bacterial gastric pollution resulting from certain hypochlorhydric conditions. Much epidemiological research has tried to establish a relationship between exposure to nitrates in drinking water and cases of gastric cancer. The present article deals with research into this relationship in France, in a region where the rate of nitrates in water supplies is among the highest. Death statistics (from cancers of the digestive and urinal tracts) are issued by INSERM and these of the population by INSEE. Towns are classified according to nitrate concentration and the number of deaths is established according to tumour detection by sex and age. Research into death rate divergencies is found by chi 2 and the correlated coefficient. The average relative risk for any age group is calculated for all types of cancer. Research on frequency is carried out from tumour records. Comparative frequency rates are established by direct standardisation according to the structural age of any one European population. Results are analysed in relation to (1) mortality rates and (2) incidence rates. (1) None of the cancers studied, be they of the digestive or urinary systems, whatever the age on sex, is significantly linked to the quantity of nitrates in water supplies. When all these cancers are taken into account, the death rate does not vary significantly for increasing concentration of nitrates. Towns exceeding the maximum concentration permitted by law do not have a higher mortality rate than other towns. The overall can incidence rate in the Nord-Pas-de-Calais regions of France is 11.8 per 100,000 inhabitants. The average European rate is 18.3 per 100,000 for men in the Nord region and 20.5 in the Pas-de-Calais; for women, 5.9 and 7.2 respectively. These rates are comparable to those in other French regions. The incidence rate for gastric cancer is not significantly different for inhabitants of towns exposed to water containing more or less than 50 mg/l. The absence of links between cancer and nitrates water research into possible methodological expedients necessary. A certain number of factors (consumer habits, diet, population mobility) can, for the same concentration of nitrates, modify the actual quantity consumed, and so the corresponding long-term risk. However, no inverse effect of these factors which would be susceptible to counter the link to the extent of concealing it, is know for the moment.(ABSTRACT TRUNCATED AT 400 WORDS)

[Nitrates in the drinking water and cancer]. / Nitrates de l'eau de boisson et cancer.

Nitrates originating from food and particularly from water are supposedly precursors of carcinogenic N-nitroso compound (NOC) formed within the organism. According to Correa and al. these transformations could be a consequence of bacterial gastric pullulation resulting from certain hypochlorhydric conditions. Much epidemiological research has tried to establish a relationship between exposure to nitrates in drinking water and cases of gastric cancer. The present article deals with research into this relationship in France, in a region where the rate of nitrates in water supplies is among the highest. Death statistics (from cancers of the digestive and urinal tracts) are issued by INSERM and these of the population by INSEE. Towns are classified according to nitrate concentration and the number of deaths is established according to tumour detection by sex and age. Research into death rate divergencies is found by chi 2 and the correlated coefficient. The average relative risk for any age group is calculated for all types of cancer. Research on frequency is carried out from tumour records. Comparative frequency rates are established by direct standardisation according to the structural age of any one European population. Results are analysed in relation to (1) mortality rates and (2) incidence rates. (1) None of the cancers studied, of the digestive or urinary systems, whatever the age on sex, is significantly linked to the quantity of nitrates in water supplies. When all these cancers are taken into account, the death rate does not vary significantly for increasing concentration of nitrates. Towns exceeding the maximum concentration permitted by law do not have a higher mortality rate than other towns.(ABSTRACT TRUNCATED AT 250 WORDS)

[How to reduce morbidity in celioscopic biliary surgery. Apropos of a series of 446 consecutive operations]. / Comment réduire la morbidité en chirurgie biliaire par voie coelioscopique. A propos d'une série de 446 interventions consécutives.

We reported a series of 446 consecutive cholecystectomies performed laparoscopically between June 1990 and January 1993. There were 354 females and 92 men, mean age 53 +/- 17 years. Laparoscopic cholangiography was attempted in 410 cases (92%) and led to the discover of a stone in the main bile duct in 18 cases (4%) and an abnormal insertion of the bladder duct in 30% (6.7%). Conversion to laparotomy was required in 84 patients (18.8%) due to difficult dissection (52), peroperative incidents or accidents (15) and abnormal hepatogram (17). No accident inherent to the operation was encountered in this series. One death occurred after laparotomic conversion for acute angiocholitis. The rate of post-operative complications was 5.6% and reoperations were required in 7 patients (1.5%).