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1.
Anal Bioanal Chem ; 410(13): 3171-3183, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29594428

RESUMEN

The substance group of very volatile organic compounds (VVOCs) is moving into the focus of indoor air analysis, facing ongoing regulations at international and European levels targeting on indoor air quality and human health. However, there exists at present no validated analysis for the identification and quantification of VVOCs in indoor air. Therefore, the present study targeted on the development of an analytical method in order to sample the maximum possible quantity of VVOCs in indoor air on solid sorbents with subsequent analysis by thermal desorption and coupled gas chromatography/mass spectrometry (TDS-GC/MS). For this purpose, it was necessary to investigate the performance of available sorbents and to optimize the parameters of GC/MS analysis. Stainless steel tubes filled with Carbograph 5TD were applied successfully for low-volume sampling (2-4 l) with minimal breakthrough (< 1%). With the developed method, VVOCs between C3 and C6 of different volatility and polarity  can be detected even in trace quantities with low limits of quantitation (LOQ; 1-3 µg m-3). Limitations occur for low molecular weight compounds ≤C3, especially for polar substances, such as carboxylic acids and for some aldehydes and alcohols. Consequently, established methods for the quantification of these compounds in indoor air cannot be fully substituted yet. At least three different analytical techniques are needed to cover the large spectrum of relevant VVOCs in indoor air. In addition, unexpected reaction products might occur and need to be taken into account to avoid misinterpretation of chromatographic signals. Graphical abstract Solid sorbent sampling of VVOCs (C3-C6) in indoor air with subsequent TDS-GC/MS analysis.

2.
Environ Sci Process Impacts ; 21(8): 1353-1363, 2019 Aug 14.
Artículo en Inglés | MEDLINE | ID: mdl-31070628

RESUMEN

With regard to the application of semi-volatile organic compounds (SVOCs) in products for indoor use, a distinct trend towards substitutions can currently be observed. Among the possible phthalate alternatives, in particular the adipic acid esters have gained in market importance. The chemical-physical and thermodynamic properties of the phthalates and adipates allow the conclusion to be drawn that they are distributed between different compartments (gas phase, particle phase, dust, material surfaces) of the indoor space. There are, however, hardly any data in existence which were collected in a real environment over six months and longer. Diisobutyl adipate (DiBA), di-n-butyl adipate (DnBA), dipentyl phthalate (DPP), butyl benzyl phthalate (BBzP) and di-2-ethylhexyl adipate (DEHA) were selected as model substances. By means of spiked latex paint and spiked house dust, these SVOCs were introduced into two identically equipped test rooms. One room was cleaned regularly, whilst the reference room was not entered for a 133 day experimental period. The concentrations of the five target substances were determined in the air and in material samples (carpet, vacuum-cleaner bags, filters). During the operation of an air purifier, the air concentration of the target substances in a room could be reduced by more than 50%. In the reference room, a correlation between the logarithmic air concentration and the reciprocal room temperature was found. The results show with great clarity the complexity of the conditions in an indoor room. Models can therefore depict the exposure as a statistical average but not, however, describe the individual case.


Asunto(s)
Filtros de Aire , Contaminación del Aire Interior/análisis , Contaminación del Aire Interior/prevención & control , Polvo/análisis , Modelos Teóricos , Compuestos Orgánicos Volátiles/análisis , Adipatos/análisis , Humanos , Ácidos Ftálicos/análisis
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