1.
Bioorg Med Chem Lett
; 27(1): 16-20, 2017 Jan 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-27894871
RESUMEN
A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species. In this communication, we report the part of the optimization program which led to the discovery of triflumezopyrim as a highly potent insecticide controlling various hopper species. Our efforts in discovery, synthesis, structure-activity relationship elucidation, and biological activity evaluation are also presented.