Detalles de la búsqueda
1.
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics.
FASEB J
; 31(6): 2696-2708, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28264975
2.
Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation.
Hepatology
; 64(5): 1743-1756, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27532775
3.
Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Drug Metab Dispos
; 45(4): 419-429, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28137721
4.
Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines.
Toxicol Appl Pharmacol
; 274(3): 408-16, 2014 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24355420
5.
Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models.
Part Fibre Toxicol
; 11: 15, 2014 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24684892
6.
Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126).
Int J Mol Sci
; 15(8): 13916-31, 2014 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25116688
7.
Comparative analysis of YAP/TEAD inhibitors in 2D and 3D cultures of primary human hepatocytes reveals a novel non-canonical mechanism of CYP induction.
Biochem Pharmacol
; 215: 115755, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37607620
8.
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections.
Nat Commun
; 14(1): 6785, 2023 10 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37880247
9.
Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control.
iScience
; 25(12): 105654, 2022 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36479146
10.
Magnesium enhances cardiomyocyte proliferation and suppresses cardiac fibrosis induced by chronic ACTH exposure in rats.
Magnes Res
; 34(2): 74-83, 2021 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34463274
11.
A 3D Cell Culture Model Identifies Wnt/ß-Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration.
Adv Sci (Weinh)
; 7(15): 2000248, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32775153
12.
Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.
Clin Pharmacol Ther
; 108(4): 844-855, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32320483
13.
Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.
Toxicol Sci
; 163(2): 655-665, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29590495
14.
Calcium Signaling in Liver Injury and Regeneration.
Front Med (Lausanne)
; 5: 192, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30023358
15.
Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes.
Toxicol Lett
; 233(3): 258-66, 2015 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-25668756
16.
Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node.
Chem Biol Interact
; 218: 82-8, 2014 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-24824450
17.
PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells.
Exp Toxicol Pathol
; 66(8): 377-82, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24916446
18.
Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma.
Epigenetics
; 9(12): 1641-7, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25625848
19.
Cancer-associated fibroblasts expressing CXCL14 rely upon NOS1-derived nitric oxide signaling for their tumor-supporting properties.
Cancer Res
; 74(11): 2999-3010, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24710408
20.
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells.
PLoS One
; 6(1): e14617, 2011 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21297970
Resultados
1 -
20
de 20
1
Próxima >
>>