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1.
Transl Psychiatry ; 1: e53, 2011 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-22833208

RESUMEN

Video game playing is a frequent recreational activity. Previous studies have reported an involvement of dopamine-related ventral striatum. However, structural brain correlates of video game playing have not been investigated. On magnetic resonance imaging scans of 154 14-year-olds, we computed voxel-based morphometry to explore differences between frequent and infrequent video game players. Moreover, we assessed the Monetary Incentive Delay (MID) task during functional magnetic resonance imaging and the Cambridge Gambling Task (CGT). We found higher left striatal grey matter volume when comparing frequent against infrequent video game players that was negatively correlated with deliberation time in CGT. Within the same region, we found an activity difference in MID task: frequent compared with infrequent video game players showed enhanced activity during feedback of loss compared with no loss. This activity was likewise negatively correlated with deliberation time. The association of video game playing with higher left ventral striatum volume could reflect altered reward processing and represent adaptive neural plasticity.


Asunto(s)
Ganglios Basales/fisiología , Encéfalo/fisiología , Imagen por Resonancia Magnética/métodos , Juegos de Video/psicología , Adolescente , Femenino , Juego de Azar/psicología , Humanos , Imagen por Resonancia Magnética/instrumentación , Masculino , Pruebas Neuropsicológicas , Núcleo Accumbens/fisiología , Recompensa , Factores de Tiempo
2.
Phys Chem Chem Phys ; 8(16): 1929-35, 2006 Apr 28.
Artículo en Inglés | MEDLINE | ID: mdl-16633680

RESUMEN

In this paper a quantitative explanation for a diamagnetic ortho/para H2 conversion is given. The description is based on the quantum-mechanical density matrix formalism originally developed by Alexander and Binsch for studies of exchange processes in NMR spectra. Only the nuclear spin system is treated quantum-mechanically. Employing the model of a three spin system, the reactions of the hydrogen gas with the catalysts are treated as a phenomenological rate process, described by a rate constant. Numerical calculations reveal that for nearly all possible geometrical arrangements of the three spin system an efficient spin conversion is obtained. Only in the chemically improbable case of a linear group H-X-H no spin conversion is obtained. The efficiency of the spin conversion depends strongly on the lifetime of the H-X-H complex and on the presence of exchange interactions between the two hydrogens. Even moderate exchange couplings cause a quench of the spin conversion. Thus a sufficiently strong binding of the dihydrogen to the S spin is necessary to render the quenching by the exchange interaction ineffective.


Asunto(s)
Espectroscopía de Resonancia por Spin del Electrón , Hidrógeno/química , Catálisis , Cinética , Espectroscopía de Resonancia Magnética , Matemática , Modelos Químicos
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