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1.
Int J Audiol ; 61(3): 205-219, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34081564

RESUMEN

OBJECTIVE: A model-based determination of the average supra-threshold ("distortion") component of hearing impairment which limits the benefit of hearing aid amplification. DESIGN: Published speech recognition thresholds (SRTs) were predicted with the framework for auditory discrimination experiments (FADE), which simulates recognition processes, the speech intelligibility index (SII), which exploits frequency-dependent signal-to-noise ratios (SNR), and a modified SII with a hearing-loss-dependent band importance function (PAV). Their attenuation-component-based prediction errors were interpreted as estimates of the distortion component. STUDY SAMPLE: Unaided SRTs of 315 hearing-impaired ears measured with the German matrix sentence test in stationary noise. RESULTS: Overall, the models showed root-mean-square errors (RMSEs) of 7 dB, but for steeply sloping hearing loss FADE and PAV were more accurate (RMSE = 9 dB) than the SII (RMSE = 23 dB). Prediction errors of FADE and PAV increased linearly with the average hearing loss. The consideration of the distortion component estimate significantly improved the accuracy of FADE's and PAV's predictions. CONCLUSIONS: The supra-threshold distortion component-estimated by prediction errors of FADE and PAV-seems to increase with the average hearing loss. Accounting for a distortion component improves the model predictions and implies a need for effective compensation strategies for supra-threshold processing deficits with increasing audibility loss.


Asunto(s)
Audífonos , Pérdida Auditiva Sensorineural , Pérdida Auditiva , Percepción del Habla , Umbral Auditivo , Pérdida Auditiva/diagnóstico , Humanos , Inteligibilidad del Habla
2.
Int J Audiol ; : 1-13, 2022 Nov 28.
Artículo en Inglés | MEDLINE | ID: mdl-36441177

RESUMEN

OBJECTIVE: To develop the Cantonese matrix (YUEmatrix) test according to the international standard procedure and examine possible different outcomes in another tonal language. DESIGN: A 50-word Cantonese base-matrix was established. Word-specific speech recognition functions, speech recognition thresholds (SRT), and slopes were obtained. The speech material was homogenised in intelligibility by applying level corrections up to ± 3 dB. Subsequently, the YUEmatrix test was evaluated in five aspects: training effect, test-list equivalence, test-retest reliability, establishment of reference data for normal-hearing Cantonese-speakers, and comparison with the Cantonese-Hearing-In-Noise-Test. STUDY SAMPLE: Overall, 64 normal-hearing native Cantonese-speaking listeners. RESULTS: SRT measurements with adaptive procedures resulted in a reference SRT of -9.7 ± 0.7 dB SNR for open-set and -11.1 ± 1.2 dB SNR for the closed-set response format. Fixed SNR measurements suggested a test-specific speech intelligibility function slope of 15.5 ± 0.7%/dB. Seventeen 10-sentences base test lists were confirmed to be equivalent with respect to speech intelligibility. Training effect was not observed after two measurements of 20-sentences lists. CONCLUSIONS: The YUEmatrix yields comparable results to matrix tests in other languages including Mandarin. Level adjustments to homogenise sentences appear to be less effective for tonal languages than for most other languages developed so far.

3.
Int J Audiol ; 60(1): 16-26, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-32945703

RESUMEN

OBJECTIVE: As a step towards the development of an audiological diagnostic supporting tool employing machine learning methods, this article aims at evaluating the classification performance of different audiological measures as well as Common Audiological Functional Parameters (CAFPAs). CAFPAs are designed to integrate different clinical databases and provide abstract representations of measures. DESIGN: Classification and evaluation of classification performance in terms of sensitivity and specificity are performed on a data set from a previous study, where statistical models of diagnostic cases were estimated from expert-labelled data. STUDY SAMPLE: The data set contains 287 cases. RESULTS: The classification performance in clinically relevant comparison sets of two competing categories was analysed for audiological measures and CAFPAs. It was found that for different audiological diagnostic questions a combination of measures using different weights of the parameters is useful. A set of four to six measures was already sufficient to achieve maximum classification performance which indicates that the measures contain redundant information. CONCLUSIONS: The current set of CAFPAs was confirmed to yield in most cases approximately the same classification performance as the respective optimum set of audiological measures. Overall, the concept of CAFPAs as compact, abstract representation of auditory deficiencies is confirmed.


Asunto(s)
Audiología , Bases de Datos Factuales , Humanos , Aprendizaje Automático , Modelos Estadísticos , Sensibilidad y Especificidad
4.
Int J Audiol ; 59(7): 534-547, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32091289

RESUMEN

Objective: Statistical knowledge about many patients could be exploited using machine learning to provide supporting information to otolaryngologists and other hearing health care professionals, but needs to be made accessible. The Common Audiological Functional Parameters (CAFPAs) were recently introduced for the purpose of integrating data from different databases by providing an abstract representation of audiological measurements. This paper aims at collecting expert labels for a sample database and to determine statistical models from the labelled data set.Design: By an expert survey, CAFPAs as well as labels for audiological findings and treatment recommendations were collected for patients from the database of Hörzentrum Oldenburg.Study sample: A total of 287 single patient cases were assessed by twelve highly experienced audiological experts.Results: The labelled data set was used to derive probability density functions for categories given by the expert labels. The collected data set is suitable for estimating training distributions due to realistic variability contained in data for different, distinct categories. Suitable distribution functions were determined. The derived training distributions were compared regarding different audiological questions.Conclusions: The method-expert survey, sorting data into categories, and determining training distributions - could be extended to other data sets, which could then be integrated via the CAFPAs and used in a classification task.


Asunto(s)
Audiología/estadística & datos numéricos , Corrección de Deficiencia Auditiva/estadística & datos numéricos , Conjuntos de Datos como Asunto , Sistemas Especialistas , Modelos Estadísticos , Interpretación Estadística de Datos , Bases de Datos Factuales , Pruebas Auditivas/estadística & datos numéricos , Humanos , Probabilidad , Reproducibilidad de los Resultados
5.
Int J Audiol ; 59(12): 930-940, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-32815756

RESUMEN

OBJECTIVE: To validate the Russian matrix sentence test (RUMatrix) for the assessment of speech recognition in quiet and in noise in clinical praxis. The effect of hearing impairment, age, and masking-noise level on speech recognition was examined. DESIGN: All participants underwent pure tone audiometry, a monosyllabic speech test in quiet, and speech recognition measurements with RUMatrix in quiet (SRTQ) and in noise (SRTN). STUDY SAMPLE: One hundred and forty-two listeners divided into four groups: 1. Young normal-hearing listeners, 2. Older normal-hearing listeners, 3. Young hearing-impaired listeners, and 4. Older hearing-impaired listeners. RESULTS: Significant differences between groups of listeners were found in the SRTQ and SRTN. A strong correlation between hearing threshold and SRTQ (R2=0.88, p < 0.001) indicates a strong link between speech recognition in quiet and audibility. The pure-tone average explained less variance in SRTN (R2=0.67, p < 0.001), pointing out an additional influence of suprathreshold distortion. A high test sensitivity of 0.99 was found for SRTN and SRTQ. The monosyllabic test had a low sensitivity (0.21), indicating that the test is not suitable for separating normal-hearing and hearing-impaired listeners. CONCLUSIONS: RuMatrix is a reliable speech recognition assessment tool with a high sensitivity and validity for the main aspects of hearing impairment.


Asunto(s)
Pérdida Auditiva Sensorineural , Pérdida Auditiva , Percepción del Habla , Audiometría de Tonos Puros , Umbral Auditivo , Pérdida Auditiva Sensorineural/diagnóstico , Humanos , Ruido/efectos adversos , Federación de Rusia
6.
Int J Audiol ; 58(4): 231-245, 2019 04.
Artículo en Inglés | MEDLINE | ID: mdl-30900518

RESUMEN

OBJECTIVE: As a step towards objectifying audiological rehabilitation and providing comparability between different test batteries and clinics, the Common Audiological Functional Parameters (CAFPAs) were introduced as a common and abstract representation of audiological knowledge obtained from diagnostic tests. DESIGN: Relationships between CAFPAs as an intermediate representation between diagnostic tests and audiological findings, diagnoses and treatment recommendations (summarised as "diagnostic cases") were established by means of an expert survey. Expert knowledge was collected for 14 given categories covering different diagnostic cases. For each case, the experts were asked to indicate expected ranges of diagnostic test outcomes, as well as traffic light-encoded CAFPAs. STUDY SAMPLE: Eleven German experts in the field of audiological rehabilitation from Hanover and Oldenburg participated in the survey. RESULTS: Audiological findings or treatment recommendations could be distinguished by a statistical model derived from the experts' answers for CAFPAs as well as audiological tests. CONCLUSIONS: The CAFPAs serve as an abstract, comprehensive representation of audiological knowledge. If more detailed information on certain functional aspects of the auditory system is required, the CAFPAs indicate which information is missing. The statistical graphical representations for CAFPAs and audiological tests are suitable for audiological teaching material; they are universally applicable for real clinical databases.


Asunto(s)
Audiología/estadística & datos numéricos , Corrección de Deficiencia Auditiva/estadística & datos numéricos , Sistemas Especialistas , Trastornos de la Audición/diagnóstico , Pruebas Auditivas/estadística & datos numéricos , Aprendizaje Automático , Interpretación Estadística de Datos , Trastornos de la Audición/clasificación , Trastornos de la Audición/terapia , Humanos , Valor Predictivo de las Pruebas , Probabilidad , Reproducibilidad de los Resultados
7.
Int J Audiol ; 57(11): 838-850, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-30178681

RESUMEN

OBJECTIVE: Development of the Mandarin Chinese matrix (CMNmatrix) sentence test for speech intelligibility measurements in noise according to the international standard procedure. DESIGN: A 50-word base matrix representing the distribution of phonemes and lexical tones of spoken Mandarin was established. Hundred sentences capturing all the co-articulations of two consecutive words were recorded. Word-specific speech recognition functions, speech reception thresholds (SRT: signal-to-noise ratio (SNR), that provides 50% speech intelligibility) and slopes were obtained from measurements at fixed SNRs. The speech material was homogenised in intelligibility by applying level corrections up to ± 2 dB. Subsequently, the CMNmatrix test was evaluated, the comparability of test lists was measured at two fixed SNRs. To investigate the training effect and establish the reference data, speech recognition was measured adaptively. STUDY SAMPLE: Overall, the study sample contained 80 normal-hearing native Mandarin-speaking listeners. RESULTS: Multi-centre evaluation measurements confirmed that test lists are equivalent in intelligibility, with a mean SRT of -10.1 ± 0.1 dB SNR and a slope of 13.1 ± 0.9 %/dB. The reference SRT is -9.3 ± 0.8 and -11.2 ± 1.2 dB SNR for the open- and closed-set response format, respectively. CONCLUSION: The CMNmatrix test is suitable for accurate and internationally comparable speech recognition measurements in noise.


Asunto(s)
Ruido/efectos adversos , Enmascaramiento Perceptual , Fonética , Inteligibilidad del Habla , Percepción del Habla , Prueba del Umbral de Recepción del Habla , Estimulación Acústica , Adulto , Comprensión , Femenino , Humanos , Masculino , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Acústica del Lenguaje , Calidad de la Voz , Adulto Joven
8.
Plant Mol Biol Report ; 34: 720-736, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27429510

RESUMEN

Full-size members of the ABCG (ATP-binding cassette, subfamily G) subfamily of ABC transporters have been found only in plants and fungi. The plant genes encoding full-size ABCGs identified so far appeared to be differentially regulated under various environmental constraints, plant growth regulators, and microbial elicitors, indicating a broad functional role of these proteins in plant responses to abiotic and biotic stress. Nevertheless, the structure and physiological function of full-size ABCGs in many plant species are still unknown. We have recently identified 16 genes encoding full-size ABCG proteins in cucumber and found that the transcripts of two of them, CsABCG36 (CsPDR8) and CsABCG40 (CsPDR12), are most abundant in roots and are significantly affected by phytohormones and auxin herbicide. In this study, we analyzed the structure and phylogeny of all the full-size cucumber ABCG transporters and studied the organ expression profiles of the remaining 14 CsABCG genes. In addition, we investigated the effect of different plant growth regulators and the diterpene sclareolide on CsABCG expression in cucumber roots. Until now, the full-size plant ABCG transporters have been grouped into five different clusters. The new phylogenetic analysis of full-size ABCGs from model plants and cucumber clustered these proteins into six different subgroups. Interestingly, the expression profiles of cucumber ABCG genes assigned to the same clusters were not correlated, suggesting functional diversification or different regulatory mechanisms of the full-size cucumber ABCG proteins.

9.
J Acoust Soc Am ; 139(5): 2708, 2016 05.
Artículo en Inglés | MEDLINE | ID: mdl-27250164

RESUMEN

A framework for simulating auditory discrimination experiments, based on an approach from Schädler, Warzybok, Hochmuth, and Kollmeier [(2015). Int. J. Audiol. 54, 100-107] which was originally designed to predict speech recognition thresholds, is extended to also predict psychoacoustic thresholds. The proposed framework is used to assess the suitability of different auditory-inspired feature sets for a range of auditory discrimination experiments that included psychoacoustic as well as speech recognition experiments in noise. The considered experiments were 2 kHz tone-in-broadband-noise simultaneous masking depending on the tone length, spectral masking with simultaneously presented tone signals and narrow-band noise maskers, and German Matrix sentence test reception threshold in stationary and modulated noise. The employed feature sets included spectro-temporal Gabor filter bank features, Mel-frequency cepstral coefficients, logarithmically scaled Mel-spectrograms, and the internal representation of the Perception Model from Dau, Kollmeier, and Kohlrausch [(1997). J. Acoust. Soc. Am. 102(5), 2892-2905]. The proposed framework was successfully employed to simulate all experiments with a common parameter set and obtain objective thresholds with less assumptions compared to traditional modeling approaches. Depending on the feature set, the simulated reference-free thresholds were found to agree with-and hence to predict-empirical data from the literature. Across-frequency processing was found to be crucial to accurately model the lower speech reception threshold in modulated noise conditions than in stationary noise conditions.


Asunto(s)
Simulación por Computador , Discriminación en Psicología , Modelos Teóricos , Ruido/efectos adversos , Enmascaramiento Perceptual , Reconocimiento en Psicología , Percepción del Habla , Estimulación Acústica , Acústica , Umbral Auditivo , Humanos , Psicoacústica , Espectrografía del Sonido , Prueba del Umbral de Recepción del Habla
10.
Int J Audiol ; 54 Suppl 2: 88-99, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26344170

RESUMEN

OBJECTIVE: The current study investigates the extent to which the linguistic complexity of three commonly employed speech recognition tests and second language proficiency influence speech recognition thresholds (SRTs) in noise in non-native listeners. DESIGN: SRTs were measured for non-natives and natives using three German speech recognition tests: the digit triplet test (DTT), the Oldenburg sentence test (OLSA), and the Göttingen sentence test (GÖSA). STUDY SAMPLE: Sixty-four non-native and eight native listeners participated. RESULTS: Non-natives can show native-like SRTs in noise only for the linguistically easy speech material (DTT). Furthermore, the limitation of phonemic-acoustical cues in digit triplets affects speech recognition to the same extent in non-natives and natives. For more complex and less familiar speech materials, non-natives, ranging from basic to advanced proficiency in German, require on average 3-dB better signal-to-noise ratio for the OLSA and 6-dB for the GÖSA to obtain 50% speech recognition compared to native listeners. CONCLUSIONS: In clinical audiology, SRT measurements with a closed-set speech test (i.e. DTT for screening or OLSA test for clinical purposes) should be used with non-native listeners rather than open-set speech tests (such as the GÖSA or HINT), especially if a closed-set version in the patient's own native language is available.


Asunto(s)
Multilingüismo , Ruido/efectos adversos , Enmascaramiento Perceptual , Percepción del Habla , Prueba del Umbral de Recepción del Habla/métodos , Estimulación Acústica , Adulto , Umbral Auditivo , Comprensión , Señales (Psicología) , Femenino , Humanos , Masculino , Valor Predictivo de las Pruebas , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Inteligibilidad del Habla , Adulto Joven
11.
Int J Audiol ; 54 Suppl 2: 100-7, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26383042

RESUMEN

OBJECTIVE: The feasibility of predicting the outcome of the German matrix sentence test for different types of stationary background noise using an automatic speech recognition (ASR) system was studied. DESIGN: Speech reception thresholds (SRT) of 50% intelligibility were predicted in seven noise conditions. The ASR system used Mel-frequency cepstral coefficients as a front-end and employed whole-word Hidden Markov models on the back-end side. The ASR system was trained and tested with noisy matrix sentences on a broad range of signal-to-noise ratios. STUDY SAMPLE: The ASR-based predictions were compared to data from the literature ( Hochmuth et al, 2015 ) obtained with 10 native German listeners with normal hearing and predictions of the speech intelligibility index (SII). RESULTS: The ASR-based predictions showed a high and significant correlation (R² = 0.95, p < 0.001) with the empirical data across different noise conditions, outperforming the SII-based predictions which showed no correlation with the empirical data (R² = 0.00, p = 0.987). CONCLUSIONS: The SRTs for the German matrix test for listeners with normal hearing in different stationary noise conditions could well be predicted based on the acoustical properties of the speech and noise signals. Minimum assumptions were made about human speech processing already incorporated in a reference-free ordinary ASR system.


Asunto(s)
Lenguaje , Percepción del Habla , Prueba del Umbral de Recepción del Habla/métodos , Software de Reconocimiento del Habla , Estimulación Acústica , Acústica , Umbral Auditivo , Automatización , Comprensión , Estudios de Factibilidad , Humanos , Ruido/efectos adversos , Enmascaramiento Perceptual , Valor Predictivo de las Pruebas , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Espectrografía del Sonido , Inteligibilidad del Habla
12.
Int J Audiol ; 54 Suppl 2: 35-43, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25843088

RESUMEN

OBJECTIVE: To develop the Russian matrix sentence test for speech intelligibility measurements in noise. DESIGN: Test development included recordings, optimization of speech material, and evaluation to investigate the equivalency of the test lists and training. For each of the 500 test items, the speech intelligibility function, speech reception threshold (SRT: signal-to-noise ratio, SNR, that provides 50% speech intelligibility), and slope was obtained. The speech material was homogenized by applying level corrections. In evaluation measurements, speech intelligibility was measured at two fixed SNRs to compare list-specific intelligibility functions. To investigate the training effect and establish reference data, speech intelligibility was measured adaptively. STUDY SAMPLE: Overall, 77 normal-hearing native Russian listeners. RESULTS: The optimization procedure decreased the spread in SRTs across words from 2.8 to 0.6 dB. Evaluation measurements confirmed that the 16 test lists were equivalent, with a mean SRT of -9.5 ± 0.2 dB and a slope of 13.8 ± 1.6%/dB. The reference SRT, -8.8 ± 0.8 dB for the open-set and -9.4 ± 0.8 dB for the closed-set format, increased slightly for noise levels above 75 dB SPL. CONCLUSIONS: The Russian matrix sentence test is suitable for accurate and reliable speech intelligibility measurements in noise.


Asunto(s)
Lenguaje , Percepción del Habla , Prueba del Umbral de Recepción del Habla/métodos , Estimulación Acústica , Acústica , Adulto , Umbral Auditivo , Comprensión , Voluntarios Sanos , Audición , Humanos , Ruido/efectos adversos , Enmascaramiento Perceptual , Valor Predictivo de las Pruebas , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Relación Señal-Ruido , Inteligibilidad del Habla , Adulto Joven
13.
Int J Audiol ; 54 Suppl 2: 3-16, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26383182

RESUMEN

OBJECTIVE: A review of the development, evaluation, and application of the so-called 'matrix sentence test' for speech intelligibility testing in a multilingual society is provided. The format allows for repeated use with the same patient in her or his native language even if the experimenter does not understand the language. DESIGN: Using a closed-set format, the syntactically fixed, semantically unpredictable sentences (e.g. 'Peter bought eight white ships') provide a vocabulary of 50 words (10 alternatives for each position in the sentence). The principles (i.e. construction, optimization, evaluation, and validation) for 14 different languages are reviewed. Studies of the influence of talker, language, noise, the training effect, open vs. closed conduct of the test, and the subjects' language proficiency are reported and application examples are discussed. RESULTS: The optimization principles result in a steep intelligibility function and a high homogeneity of the speech materials presented and test lists employed, yielding a high efficiency and excellent comparability across languages. The characteristics of speakers generally dominate the differences across languages. CONCLUSION: The matrix test format with the principles outlined here is recommended for producing efficient, reliable, and comparable speech reception thresholds across different languages.


Asunto(s)
Multilingüismo , Percepción del Habla , Prueba del Umbral de Recepción del Habla/métodos , Estimulación Acústica , Acústica , Umbral Auditivo , Comprensión , Humanos , Ruido/efectos adversos , Variaciones Dependientes del Observador , Enmascaramiento Perceptual , Valor Predictivo de las Pruebas , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Acústica del Lenguaje , Inteligibilidad del Habla , Calidad de la Voz
14.
Int J Audiol ; 54 Suppl 2: 44-50, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26371592

RESUMEN

OBJECTIVE: Development of an Italian matrix sentence test for the assessment of speech intelligibility in noise. DESIGN: The development of the test included the selection, recording, optimization with level adjustment, and evaluation of speech material. The training effect was assessed adaptively during the evaluation measurements with six lists of 20 sentences, using open- and closed-set response formats. Reference data were established for normal-hearing listeners with adaptive measurements. Equivalence of the test lists was investigated using the open-set response format at three signal-to-noise ratios (SNRs). STUDY SAMPLE: A total of 55 normal-hearing Italian mother-tongue listeners. RESULTS: The evaluation measurements at fixed SNRs resulted in a mean speech reception threshold (SRT) of -7.3 ± 0.2 dB SNR and slope of 13.3 ± 1.2 %/dB. The major training effect of 1.5 dB was observed for the first two consecutive measurements. Mean SRTs of -6.7 ± 0.7 dB SNR and -7.4 ± 0.7 dB SNR were found from the third to the sixth adaptive measurement for open- and closed-set test response formats, respectively. CONCLUSIONS: A good agreement has been found between the SRTs and slope and those of other matrix tests. Since sentences are difficult to memorize, the Italian matrix test is suitable for repeated measurements.


Asunto(s)
Lenguaje , Ruido/efectos adversos , Enmascaramiento Perceptual , Percepción del Habla , Prueba del Umbral de Recepción del Habla/métodos , Estimulación Acústica , Acústica , Adulto , Umbral Auditivo , Comprensión , Femenino , Voluntarios Sanos , Audición , Humanos , Masculino , Valor Predictivo de las Pruebas , Reconocimiento en Psicología , Reproducibilidad de los Resultados , Relación Señal-Ruido , Inteligibilidad del Habla , Adulto Joven
15.
J Acoust Soc Am ; 135(3): 1556-67, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24606290

RESUMEN

Recently the influence of delay and azimuth of a single speech reflection on speech reception thresholds (SRTs) was systematically investigated using frontal, diffuse, and lateral noise [Warzybok et al. (2013). J. Acoust. Soc. Am. 133, 269-282]. The experiments showed that the benefit of an early reflection was independent of its azimuth and mostly independent of noise type, but that the detrimental effect of a late reflection depended on its direction relative to the noise. This study tests if different extensions of a binaural speech intelligibility model can predict these data. The extensions differ in the order in which binaural processing and temporal integration of early reflections take place. Models employing a correction for the detrimental effects of reverberation on speech intelligibility after performing the binaural processing predict SRTs in symmetric masking conditions (frontal, diffuse), but cannot predict the measured interaction of temporal and spatial integration. In contrast, a model extension accounting for the distinction between useful and detrimental reflections before the binaural processing stage predicts the data with an overall R(2) of 0.95. This indicates that any model framework predicting speech intelligibility in rooms should incorporate an interaction between binaural and temporal integration of reflections at a comparatively early stage.


Asunto(s)
Modelos Psicológicos , Acústica del Lenguaje , Inteligibilidad del Habla , Percepción del Habla , Calidad de la Voz , Estimulación Acústica , Umbral Auditivo , Señales (Psicología) , Humanos , Ruido/efectos adversos , Enmascaramiento Perceptual , Prueba del Umbral de Recepción del Habla , Factores de Tiempo , Vibración
16.
J Acoust Soc Am ; 133(1): 269-82, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23297901

RESUMEN

In order to study the interaction between the intelligibility advantage in rooms due to the presence of early reflections and due to binaural unmasking, a series of speech reception threshold experiments was performed employing a single reflection of the frontal target speech source as a function of its delay ranging from 0 to 200 ms. The direction of the reflection and the spatial characteristic of the interfering noise (diotic, diffuse, or laterally localized) were varied in the experiments. For the frontal reflection, full temporal integration was observed for all three noise types up to a delay of at least 25 ms followed by gradual intelligibility decay at longer delays. At 200 ms delay the reflection introduced additional intelligibility deterioration. For short delays, intelligibility was not reduced when the reflection was spatially separated from the direct sound in the diffuse and lateral noise conditions. A release from the deterioration effect at 200 ms delay was found for all spatially separated reflections. The suppression of a detrimental reflection was symmetrical in diffuse noise, but azimuth-dependent in lateral noise. This indicates an interaction of spatial and temporal processing of speech reflections which challenges existing binaural speech intelligibility models.


Asunto(s)
Acústica , Arquitectura y Construcción de Instituciones de Salud , Ruido/efectos adversos , Enmascaramiento Perceptual , Inteligibilidad del Habla , Percepción del Habla , Estimulación Acústica , Adulto , Análisis de Varianza , Audiometría de Tonos Puros , Umbral Auditivo , Femenino , Humanos , Masculino , Prueba del Umbral de Recepción del Habla , Factores de Tiempo , Adulto Joven
17.
Artículo en Inglés | MEDLINE | ID: mdl-37239574

RESUMEN

Providing students with an adequate acoustic environment is crucial for ensuring speech intelligibility in primary school classrooms. Two main approaches to control acoustics in educational facilities consist of reducing background noise and late reverberation. Prediction models for speech intelligibility have been developed and implemented to evaluate the effects of these approaches. In this study, two versions of the Binaural Speech Intelligibility Model (BSIM) were used to predict speech intelligibility in realistic spatial configurations of speakers and listeners, considering binaural aspects. Both versions shared the same binaural processing and speech intelligibility backend processes but differed in the pre-processing of the speech signal. An Italian primary school classroom was characterized in terms of acoustics before (reverberation, T20 = 1.6 ± 0.1 s) and after (T20 = 0.6 ± 0.1 s) an acoustical treatment to compare BSIM predictions to well-established room acoustic measures. With shorter reverberation time, speech clarity and definition improved, as well as speech recognition thresholds (SRTs) (by up to ~6 dB), particularly when the noise source was close to the receiver and an energetic masker was present. Conversely, longer reverberation times resulted (i) in poorer SRTs (by ~11 dB on average) and (ii) in an almost non-existent spatial release from masking at an angle (SRM).


Asunto(s)
Percepción del Habla , Humanos , Enmascaramiento Perceptual , Acústica , Ruido , Instituciones Académicas
18.
Postepy Biochem ; 58(1): 61-8, 2012.
Artículo en Polaco | MEDLINE | ID: mdl-23214130

RESUMEN

Nitrate is the main source of inorganic nitrogen for plants grown in aerobic soil conditions. The growth and development of many species, including cultivated crops is strictly dependent on the effective processes of nitrate uptake, its accumulation and remobilization within the plant tissues under frequent fluctuations of NO3(-) level in soil. The proteins engaged in nitrate translocation across cellular membranes are the key players governing nitrate distribution within the plant body. Two families of proton-coupled symporters, NRT1 and NRT2, and one type of proton-coupled antiporters, CIC, have been shown to be involved in nitrate transport in higher plants. The recent progress in research on NRT1 proteins has shed the light on the localization and physiological function of those nitrate transporters in the NO3(-) uptake, NO3(-) cell-to-cell and tissue-to-tissue distribution, nitrates accumulation and efflux within the model plant Arabidopsis thaliana. This review focuses on the recent findings of the new molecular mechanisms controlling NO3(-) transport and signaling which employ nine NRT1 proteins of A. thaliana, with the emphasis on the physiological function and relevance of these proteins for the proper plant growth and development.


Asunto(s)
Proteínas de Transporte de Anión/metabolismo , Proteínas de Arabidopsis/metabolismo , Arabidopsis/metabolismo , Nitratos/metabolismo , Proteínas de Plantas/metabolismo , Transporte Biológico Activo/fisiología , Proteínas de Transporte de Membrana/metabolismo , Transducción de Señal/fisiología
19.
Trends Hear ; 26: 23312165221143901, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36537084

RESUMEN

Speech recognition in rooms requires the temporal integration of reflections which arrive with a certain delay after the direct sound. It is commonly assumed that there is a certain temporal window of about 50-100 ms, during which reflections can be integrated with the direct sound, while later reflections are detrimental to speech intelligibility. This concept was challenged in a recent study by employing binaural room impulse responses (RIRs) with systematically varied interaural phase differences (IPDs) and amplitude of the direct sound and a variable number of reflections delayed by up to 200 ms. When amplitude or IPD favored late RIR components, normal-hearing (NH) listeners appeared to be capable of focusing on these components rather than on the precedent direct sound, which contrasted with the common concept of considering early RIR components as useful and late components as detrimental. The present study investigated speech intelligibility in the same conditions in hearing-impaired (HI) listeners. The data indicate that HI listeners were generally less able to "ignore" the direct sound than NH listeners, when the most useful information was confined to late RIR components. Some HI listeners showed a remarkable inability to integrate across multiple reflections and to optimally "shift" their temporal integration window, which was quite dissimilar to NH listeners. This effect was most pronounced in conditions requiring spatial and temporal integration and could provide new challenges for individual prediction models of binaural speech intelligibility.


Asunto(s)
Pérdida Auditiva , Percepción del Habla , Humanos , Umbral Auditivo/fisiología , Percepción del Habla/fisiología , Inteligibilidad del Habla , Audición/fisiología
20.
Audiol Res ; 11(1): 73-88, 2021 Feb 25.
Artículo en Inglés | MEDLINE | ID: mdl-33668761

RESUMEN

This study aimed at the evaluation of a simplified Italian matrix test (SiIMax) for speech-recognition measurements in noise for adults and children. Speech-recognition measurements with adults and children were conducted to examine the training effect and to establish reference speech-recognition thresholds of 50% (SRT50) and 80% (SRT80) correct responses. Test-list equivalency was evaluated only with adults. Twenty adults and 96 children-aged between 5 and 10 years-participated. Evaluation measurements with the adults confirmed the equivalence of the test lists, with a mean SRT50 of -8.0 dB and a standard deviation of 0.2 dB across the test lists. The test-specific slope (the average of the list-specific slopes) was 11.3%/dB, with a standard deviation of 0.6%/dB. For both adults and children, only one test list of 14 phrases needs to be presented to account for the training effect. For the adults, adaptive measurements of the SRT50 and SRT80 showed mean values of -7.0 ± 0.6 and -4.5 ± 1.1 dB, respectively. For children, a slight influence of age on the SRT was observed. The mean SRT50s were -5.6 ± 1.2, -5.8 ± 1.2 and -6.6 ± 1.3 dB for the children aged 5-6, 7-8 and 9-10 years, respectively. The corresponding SRT80s were -1.5 ± 2.7, -3.0 ± 1.7 and -3.7 ± 1.4 dB. High test-retest reliabilities of 1.0 and 1.1 dB for the SRT80 were obtained for the adults and children, respectively. This makes the test suitable for accurate and reliable speech-recognition measurements.

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