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1.
J Geriatr Psychiatry Neurol ; 26(2): 69-77, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-23504307

RESUMEN

Previous studies suggested that patients with mild cognitive impairment (MCI) or dementia can have impaired and declining financial skills and abilities. The purpose of this study is to test a clinically applicable method, based on the contemporary legal standard, to examine directly the mental capacity to make financial decisions and its component decision-making abilities among patients with MCI and early dementia. A total of 90 patients with mild Alzheimer disease (AD), 92 participants with MCI, and 93 cognitively normal control participants were recruited for this study. Their mental capacity to make everyday financial decisions was assessed by clinician ratings and the Chinese version of the Assessment of Capacity for Everyday Decision-Making (ACED). Based on the clinician ratings, only 53.5% were found to be mentally competent in the AD group, compared with 94.6% in the MCI group. However, participants with MCI had mild but significant impairment in understanding, appreciating, and reasoning abilities as measured by the ACED. The ACED provided a reliable and clinically applicable structured framework for assessment of mental capacity to make financial decisions.


Asunto(s)
Enfermedad de Alzheimer/psicología , Disfunción Cognitiva/psicología , Toma de Decisiones , Competencia Mental/psicología , Anciano , Enfermedad de Alzheimer/diagnóstico , Disfunción Cognitiva/diagnóstico , Femenino , Financiación Personal , Hong Kong , Humanos , Masculino , Pruebas Neuropsicológicas , Índice de Severidad de la Enfermedad
2.
Int J Geriatr Psychiatry ; 26(7): 733-40, 2011 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-21495078

RESUMEN

OBJECTIVES: We reported the interim findings of a randomized controlled trial (RCT) to examine the effects of a mind body physical exercise (Tai Chi) on cognitive function in Chinese subjects at risk of cognitive decline. SUBJECTS: 389 Chinese older persons with either a Clinical Dementia Rating (CDR 0.5) or amnestic-MCI participated in an exercise program. The exercise intervention lasted for 1 year; 171 subjects were trained with 24 forms simplified Tai Chi (Intervention, I) and 218 were trained with stretching and toning exercise (Control, C). The exercise comprised of advised exercise sessions of at least three times per week. RESULTS: At 5th months (2 months after completion of training), both I and C subjects showed an improvement in global cognitive function, delayed recall and subjective cognitive complaints (paired t-tests, p < 0.05). Improvements in visual spans and CDR sum of boxes scores were observed in I group (paired t-tests, p < 0.001). Three (2.2%) and 21(10.8%) subjects from the I and C groups progressed to dementia (Pearson chi square = 8.71, OR = 5.34, 95% CI 1.56-18.29). Logistic regression analysis controlled for baseline group differences in education and cognitive function suggested I group was associated with stable CDR (OR = 0.14, 95%CI = 0.03-0.71, p = 0.02). CONCLUSIONS: Our interim findings showed that Chinese style mind body (Tai Chi) exercise may offer specific benefits to cognition, potential clinical interests should be further explored with longer observation period.


Asunto(s)
Trastornos del Conocimiento/terapia , Cognición/fisiología , Ejercicios de Estiramiento Muscular/métodos , Taichi Chuan/métodos , Anciano , Anciano de 80 o más Años , Trastornos del Conocimiento/psicología , Demencia/psicología , Demencia/terapia , Progresión de la Enfermedad , Femenino , Promoción de la Salud/métodos , Humanos , Masculino , Escalas de Valoración Psiquiátrica
3.
J Am Med Dir Assoc ; 13(6): 568.e15-20, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22579072

RESUMEN

OBJECTIVES: To compare the effectiveness of Chinese-style mind-body exercise (24 forms simplified Tai Chi) versus stretching and toning exercise in the maintenance of cognitive abilities in Chinese elders at risk of cognitive decline. DESIGN: A 1-year single-blind cluster randomized controlled trial. SETTINGS: Community centers and residential homes for elders in Hong Kong. PARTICIPANTS: A total of 389 subjects at risk of cognitive decline (Clinical Dementia Rating, CDR 0.5 or amnestic-MCI) participated in an exercise intervention program. INTERVENTION: A total of 171 subjects were trained with Tai Chi (Intervention [I]) and 218 were trained with stretching and toning exercise (Control [C]). METHODS: Cognitive and functional performance were assessed at the baseline, and at 5, 9, and 12 months. Data were analyzed using multilevel mixed models. Primary outcomes included progression to clinical dementia as diagnosed by DSM-IV criteria, and change of cognitive and functional scores. Secondary outcomes included postural balance measured by the Berg Balance Scale neuropsychiatric and mood symptoms measured by the Neuropsychiatric Inventory, and Cornell Scale for Depression in Dementia. RESULTS: At 1 year, 92 (54%) and 169 (78%) participants of the I and C groups completed the intervention. Multilevel logistic regression with completers-only analyses controlled for baseline differences in education revealed that the I group had a trend for lower risk of developing dementia at 1 year (odds ratio 0.21, 95% CI 0.05-0.92, P = .04). The I group had better preservation of CDR sum of boxes scores than the C group in both intention-to-treat (P = .04) and completers-only analyses (P = .004). In completers-only analyses, the I group had greater improvement in delay recall (P = .05) and Cornell Scale for Depression in Dementia scores (P = .02). CONCLUSION: Regular exercise, especially mind-body exercise with integrated cognitive and motor coordination, may help with preservation of global ability in elders at risk of cognitive decline; however, logistics to promote long-term practice and optimize adherence needs to be revisited.


Asunto(s)
Trastornos del Conocimiento/prevención & control , Trastornos del Conocimiento/fisiopatología , Cognición/fisiología , Ejercicios de Estiramiento Muscular , Taichi Chuan , Anciano , Progresión de la Enfermedad , Femenino , Evaluación Geriátrica , Hong Kong , Humanos , Masculino , Distribución de Poisson , Medición de Riesgo , Método Simple Ciego , Resultado del Tratamiento
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