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1.

Gut complement induced by the microbiota combats pathogens and spares commensals.

Wu, Meng; Zheng, Wen; Song, Xinyang; Bao, Bin; Wang, Yuanyou; Ramanan, Deepshika; Yang, Daping; Liu, Rui; Macbeth, John C; Do, Elyza A; Andrade, Warrison A; Yang, Tiandi; Cho, Hyoung-Soo; Gazzaniga, Francesca S; Ilves, Marit; Coronado, Daniela; Thompson, Charlotte; Hang, Saiyu; Chiu, Isaac M; Moffitt, Jeffrey R; Hsiao, Ansel; Mekalanos, John J; Benoist, Christophe; Kasper, Dennis L.

Cell ; 187(4): 897-913.e18, 2024 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-38280374

2.

Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection.

Yang, Daping; Jacobson, Amanda; Meerschaert, Kimberly A; Sifakis, Joseph Joy; Wu, Meng; Chen, Xi; Yang, Tiandi; Zhou, Youlian; Anekal, Praju Vikas; Rucker, Rachel A; Sharma, Deepika; Sontheimer-Phelps, Alexandra; Wu, Glendon S; Deng, Liwen; Anderson, Michael D; Choi, Samantha; Neel, Dylan; Lee, Nicole; Kasper, Dennis L; Jabri, Bana; Huh, Jun R; Johansson, Malin; Thiagarajah, Jay R; Riesenfeld, Samantha J; Chiu, Isaac M.

Cell ; 185(22): 4190-4205.e25, 2022 10 27.

Artículo en Inglés | MEDLINE | ID: mdl-36243004

3.

An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint.

Ramanan, Deepshika; Sefik, Esen; Galván-Peña, Silvia; Wu, Meng; Yang, Liang; Yang, Zhen; Kostic, Aleksandar; Golovkina, Tatyana V; Kasper, Dennis L; Mathis, Diane; Benoist, Christophe.

Cell ; 181(6): 1276-1290.e13, 2020 06 11.

Artículo en Inglés | MEDLINE | ID: mdl-32402238

4.

Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-G_i Complex Structures.

Hua, Tian; Li, Xiaoting; Wu, Lijie; Iliopoulos-Tsoutsouvas, Christos; Wang, Yuxia; Wu, Meng; Shen, Ling; Brust, Christina A; Nikas, Spyros P; Song, Feng; Song, Xiyong; Yuan, Shuguang; Sun, Qianqian; Wu, Yiran; Jiang, Shan; Grim, Travis W; Benchama, Othman; Stahl, Edward L; Zvonok, Nikolai; Zhao, Suwen; Bohn, Laura M; Makriyannis, Alexandros; Liu, Zhi-Jie.

Cell ; 180(4): 655-665.e18, 2020 02 20.

Artículo en Inglés | MEDLINE | ID: mdl-32004463

5.

Crystal Structure of the Human Cannabinoid Receptor CB2.

Li, Xiaoting; Hua, Tian; Vemuri, Kiran; Ho, Jo-Hao; Wu, Yiran; Wu, Lijie; Popov, Petr; Benchama, Othman; Zvonok, Nikolai; Locke, K'ara; Qu, Lu; Han, Gye Won; Iyer, Malliga R; Cinar, Resat; Coffey, Nathan J; Wang, Jingjing; Wu, Meng; Katritch, Vsevolod; Zhao, Suwen; Kunos, George; Bohn, Laura M; Makriyannis, Alexandros; Stevens, Raymond C; Liu, Zhi-Jie.

Cell ; 176(3): 459-467.e13, 2019 01 24.

Artículo en Inglés | MEDLINE | ID: mdl-30639103

6.

Architecture of Human Mitochondrial Respiratory Megacomplex I₂III₂IV₂.

Guo, Runyu; Zong, Shuai; Wu, Meng; Gu, Jinke; Yang, Maojun.

Cell ; 170(6): 1247-1257.e12, 2017 Sep 07.

Artículo en Inglés | MEDLINE | ID: mdl-28844695

7.

Structure of Mammalian Respiratory Supercomplex I₁III₂IV₁.

Wu, Meng; Gu, Jinke; Guo, Runyu; Huang, Yushen; Yang, Maojun.

Cell ; 167(6): 1598-1609.e10, 2016 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-27912063

8.

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Schreiber, Stuart L; Kotz, Joanne D; Li, Min; Aubé, Jeffrey; Austin, Christopher P; Reed, John C; Rosen, Hugh; White, E Lucile; Sklar, Larry A; Lindsley, Craig W; Alexander, Benjamin R; Bittker, Joshua A; Clemons, Paul A; de Souza, Andrea; Foley, Michael A; Palmer, Michelle; Shamji, Alykhan F; Wawer, Mathias J; McManus, Owen; Wu, Meng; Zou, Beiyan; Yu, Haibo; Golden, Jennifer E; Schoenen, Frank J; Simeonov, Anton; Jadhav, Ajit; Jackson, Michael R; Pinkerton, Anthony B; Chung, Thomas D Y; Griffin, Patrick R; Cravatt, Benjamin F; Hodder, Peter S; Roush, William R; Roberts, Edward; Chung, Dong-Hoon; Jonsson, Colleen B; Noah, James W; Severson, William E; Ananthan, Subramaniam; Edwards, Bruce; Oprea, Tudor I; Conn, P Jeffrey; Hopkins, Corey R; Wood, Michael R; Stauffer, Shaun R; Emmitte, Kyle A.

Cell ; 161(6): 1252-65, 2015 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-26046436

9.

Gut microbial fatty acid isomerization modulates intraepithelial T cells.

Song, Xinyang; Zhang, Haohao; Zhang, Yanbo; Goh, Byoungsook; Bao, Bin; Mello, Suelen S; Sun, Ximei; Zheng, Wen; Gazzaniga, Francesca S; Wu, Meng; Qu, Fangfang; Yin, Qiangzong; Gilmore, Michael S; Oh, Sungwhan F; Kasper, Dennis L.

Nature ; 619(7971): 837-843, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37380774

10.

Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.

Park, Joon Seok; Gazzaniga, Francesca S; Wu, Meng; Luthens, Amalia K; Gillis, Jacob; Zheng, Wen; LaFleur, Martin W; Johnson, Sarah B; Morad, Golnaz; Park, Elizabeth M; Zhou, Yifan; Watowich, Stephanie S; Wargo, Jennifer A; Freeman, Gordon J; Kasper, Dennis L; Sharpe, Arlene H.

Nature ; 617(7960): 377-385, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37138075

11.

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.

Baumgartner, Christina K; Ebrahimi-Nik, Hakimeh; Iracheta-Vellve, Arvin; Hamel, Keith M; Olander, Kira E; Davis, Thomas G R; McGuire, Kathleen A; Halvorsen, Geoff T; Avila, Omar I; Patel, Chirag H; Kim, Sarah Y; Kammula, Ashwin V; Muscato, Audrey J; Halliwill, Kyle; Geda, Prasanthi; Klinge, Kelly L; Xiong, Zhaoming; Duggan, Ryan; Mu, Liang; Yeary, Mitchell D; Patti, James C; Balon, Tyler M; Mathew, Rebecca; Backus, Carey; Kennedy, Domenick E; Chen, Angeline; Longenecker, Kenton; Klahn, Joseph T; Hrusch, Cara L; Krishnan, Navasona; Hutchins, Charles W; Dunning, Jax P; Bulic, Marinka; Tiwari, Payal; Colvin, Kayla J; Chuong, Cun Lan; Kohnle, Ian C; Rees, Matthew G; Boghossian, Andrew; Ronan, Melissa; Roth, Jennifer A; Wu, Meng-Ju; Suermondt, Juliette S M T; Knudsen, Nelson H; Cheruiyot, Collins K; Sen, Debattama R; Griffin, Gabriel K; Golub, Todd R; El-Bardeesy, Nabeel; Decker, Joshua H.

Nature ; 622(7984): 850-862, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37794185

12.

Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles.

Yang, Daping; Chen, Xi; Wang, Jingjing; Lou, Qi; Lou, Yunwei; Li, Li; Wang, Honglin; Chen, Jiangye; Wu, Meng; Song, Xinyang; Qian, Youcun.

Immunity ; 50(3): 692-706.e7, 2019 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-30824326

13.

Staphylococcus aureus proteases trigger eosinophil-mediated skin inflammation.

Kline, Sabrina N; Orlando, Nicholas A; Lee, Alex J; Wu, Meng-Jen; Zhang, Jing; Youn, Christine; Feller, Laine E; Pontaza, Cristina; Dikeman, Dustin; Limjunyawong, Nathachit; Williams, Kaitlin L; Wang, Yu; Cihakova, Daniela; Jacobsen, Elizabeth A; Durum, Scott K; Garza, Luis A; Dong, Xinzhong; Archer, Nathan K.

Proc Natl Acad Sci U S A ; 121(6): e2309243121, 2024 Feb 06.

Artículo en Inglés | MEDLINE | ID: mdl-38289950

14.

naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation.

Bork, Francesca; Greve, Carsten L; Youn, Christine; Chen, Sirui; N C Leal, Vinicius; Wang, Yu; Fischer, Berenice; Nasri, Masoud; Focken, Jule; Scheurer, Jasmin; Engels, Pujan; Dubbelaar, Marissa; Hipp, Katharina; Zalat, Baher; Szolek, Andras; Wu, Meng-Jen; Schittek, Birgit; Bugl, Stefanie; Kufer, Thomas A; Löffler, Markus W; Chamaillard, Mathias; Skokowa, Julia; Kramer, Daniela; Archer, Nathan K; Weber, Alexander N R.

EMBO Rep ; 2024 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-38783164

15.

Structural basis of CXC chemokine receptor 2 activation and signalling.

Liu, Kaiwen; Wu, Lijie; Yuan, Shuguang; Wu, Meng; Xu, Yueming; Sun, Qianqian; Li, Shu; Zhao, Suwen; Hua, Tian; Liu, Zhi-Jie.

Nature ; 585(7823): 135-140, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32610344

16.

Microbiota-targeted maternal antibodies protect neonates from enteric infection.

Zheng, Wen; Zhao, Wenjing; Wu, Meng; Song, Xinyang; Caro, Florence; Sun, Ximei; Gazzaniga, Francesca; Stefanetti, Giuseppe; Oh, Sungwhan; Mekalanos, John J; Kasper, Dennis L.

Nature ; 577(7791): 543-548, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31915378

17.

Microbial bile acid metabolites modulate gut RORÎ³⁺ regulatory T cell homeostasis.

Song, Xinyang; Sun, Ximei; Oh, Sungwhan F; Wu, Meng; Zhang, Yanbo; Zheng, Wen; Geva-Zatorsky, Naama; Jupp, Ray; Mathis, Diane; Benoist, Christophe; Kasper, Dennis L.

Nature ; 577(7790): 410-415, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31875848

18.

Historic samples reveal loss of wild genotype through domestic chicken introgression during the Anthropocene.

Wu, Meng Yue; Forcina, Giovanni; Low, Gabriel Weijie; Sadanandan, Keren R; Gwee, Chyi Yin; van Grouw, Hein; Wu, Shaoyuan; Edwards, Scott V; Baldwin, Maude W; Rheindt, Frank E.

PLoS Genet ; 19(1): e1010551, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36656838

19.

Covid-19 Vaccine Effectiveness in New York State.

Rosenberg, Eli S; Dorabawila, Vajeera; Easton, Delia; Bauer, Ursula E; Kumar, Jessica; Hoen, Rebecca; Hoefer, Dina; Wu, Meng; Lutterloh, Emily; Conroy, Mary Beth; Greene, Danielle; Zucker, Howard A.

N Engl J Med ; 386(2): 116-127, 2022 01 13.

Artículo en Inglés | MEDLINE | ID: mdl-34942067

20.

A radiomics and genomics-derived model for predicting metastasis and prognosis in colorectal cancer.

Li, Xue; Wu, Meng; Wu, Min; Liu, Jie; Song, Li; Wang, Jiasi; Zhou, Jun; Li, Shilin; Yang, Hang; Zhang, Jun; Cui, Xinwu; Liu, Zhenyu; Zeng, Fanxin.

Carcinogenesis ; 45(3): 170-180, 2024 03 11.

Artículo en Inglés | MEDLINE | ID: mdl-38195111

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