1.
Chem Sci
; 15(21): 7975-7981, 2024 May 29.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38817591
RESUMEN
An efficient protocol for the asymmetric synthesis of fluorenols has been developed through an enantioconvergent process enabled by Pd(ii)/chiral norbornene cooperative catalysis. This approach allows facile access to diverse functionalized chiral fluorenols with constantly excellent enantioselectivities, applying readily available racemic secondary ortho-bromobenzyl alcohols and aryl iodides as the starting materials.