Asunto(s)
Remoción del Cabello/métodos , Hidradenitis Supurativa/diagnóstico por imagen , Ultrasonografía/métodos , Adolescente , Adulto , Anciano , Niño , Femenino , Remoción del Cabello/efectos adversos , Hidradenitis Supurativa/terapia , Humanos , Rayos Láser/efectos adversos , Masculino , Persona de Mediana Edad , Adulto JovenRESUMEN
Contact (allergic) dermatitis is a skin disorder related to natural exposure to various allergens. Systemic contact dermatitis (SCD) describes a cutaneous eruption in response to systemic exposure to an allergen. The exact pathologic mechanism remains uncertain. Herein we describe a 36-year-old woman with symmetric systemic allergic contact dermatitis, unresponsive to conventional treatment, associated with dental alloy-contact hypersensitivity. We did skin patch testing and the blood lymphocyte transformation test (LTT) from the dental allergen series to assess contact allergy to restorative dental materials. On patch testing, positive allergic contact dermatitis reactions to metals occurred (nickel, potassium dichromate, and gold). Nickel hypersensitivity was confirmed by LTT, which also revealed silver-amalgam sensitization. Our case report highlights the need to consider adverse reactions to base-metal dental alloys in the differential diagnosis of cases of systemic allergic contact dermatitis.
Asunto(s)
Aleaciones Dentales/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Adulto , Corrosión , Implantes Dentales de Diente Único/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Femenino , Humanos , Mercurio/efectos adversos , Mercurio/química , Titanio/efectos adversos , Titanio/químicaAsunto(s)
Síndrome de Boca Ardiente/etiología , Coronas/efectos adversos , Aleaciones Dentales/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Paladio/efectos adversos , Aleaciones Dentales/química , Dermatitis Alérgica por Contacto/diagnóstico , Femenino , Humanos , Pruebas Inmunológicas , Persona de Mediana Edad , Pruebas del ParcheRESUMEN
BACKGROUND: Herpes simplex virus type 2 (HSV-2) infections may be a risk factor for the transmission of HIV. Data on the prevalence of HSV-2 infection among HIV-positive individuals are scarce. GOAL: The goal was to study the seroprevalence of and risk factors for HSV-2 infection among a cohort of Italian HIV-positive individuals. STUDY DESIGN: This was a cross-sectional study. HSV-2 serologic testing was performed for individuals with known date of HIV seroconversion, on the serum specimen obtained on the date closest to the estimated date of seroconversion. Antibodies to HSV-2 (anti-HSV-2) were detected by a gG2-specific ELISA. RESULTS: A total of 380 HIV-positive individuals were tested for anti-HSV-2; 126 (33.2%) of them were positive. Older age at HIV seroconversion and homosexuality were significantly associated with HSV-2 infection in the multivariate analysis. CONCLUSIONS: These data stress the need for including anti-HSV-2 testing and therapy in the management of HIV positivity, especially for reducing the risk of transmission of HIV through herpetic lesions.