1.
Org Biomol Chem
; 14(31): 7490-4, 2016 Aug 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-27405663
RESUMEN
Drawing upon a consecutive amide coupling and intramolecular cyclisation pathway, a one-pot, straightforward synthetic route has been developed for a range of pyrazole fused γ-pyrone derivatives. The reaction mechanism proposed for the chemoselective formation of γ-pyranopyrazole is furthermore fully supported by experimental and computational studies.