Detalles de la búsqueda
1.
Ghrelin alleviates intestinal ischemia-reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway.
FASEB J
; 38(11): e23681, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38814725
2.
Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway.
Bioorg Chem
; 145: 107212, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38377819
3.
Melatonin Alleviates Acute Respiratory Distress Syndrome by Inhibiting Alveolar Macrophage NLRP3 Inflammasomes Through the ROS/HIF-1α/GLUT1 Pathway.
Lab Invest
; 103(12): 100266, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37871834
4.
Different Inhibition of Nrf2 by Two Keap1 Isoforms α and ß to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.
Int J Mol Sci
; 23(18)2022 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36142252
5.
Metformin leads to accumulation of reactive oxygen species by inhibiting the NFE2L1 expression in human hepatocellular carcinoma cells.
Toxicol Appl Pharmacol
; 420: 115523, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33838154
6.
Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice.
Biochem Biophys Res Commun
; 503(1): 264-270, 2018 09 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29935181
7.
Nrf1 is paved as a new strategic avenue to prevent and treat cancer, neurodegenerative and other diseases.
Toxicol Appl Pharmacol
; 360: 273-283, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30267745
8.
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor.
Toxicol Appl Pharmacol
; 360: 160-184, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30268580
9.
Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits.
Toxicol Appl Pharmacol
; 360: 212-235, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30287392
10.
A Naturally-Occurring Dominant-Negative Inhibitor of Keap1 Competitively against Its Negative Regulation of Nrf2.
Int J Mol Sci
; 19(8)2018 Jul 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30042301
11.
Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to Humans.
Int J Mol Sci
; 19(10)2018 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30261635
12.
Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues.
Int J Mol Sci
; 19(10)2018 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30261697
13.
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity.
Biochem J
; 473(8): 961-1000, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27060105
14.
Nrf2- and Bach1 May Play a Role in the Modulation of Ultraviolet A-Induced Oxidative Stress by Acetyl-11-Keto-ß-Boswellic Acid in Skin Keratinocytes.
Skin Pharmacol Physiol
; 30(1): 13-23, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28142143
15.
NFE2L1/Nrf1 serves as a potential therapeutical target for neurodegenerative diseases.
Redox Biol
; 69: 103003, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38150994
16.
Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate.
Biochim Biophys Acta Mol Cell Res
; 1871(2): 119644, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37996059
17.
Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.
Free Radic Biol Med
; 213: 488-511, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38278308
18.
Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion.
Free Radic Biol Med
; 214: 115-128, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38331008
19.
A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms with their divergent effects on these distinct family transcription factors.
Free Radic Biol Med
; 213: 190-207, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38242246
20.
MCU inhibition protects against intestinal ischemiaâreperfusion by inhibiting Drp1-dependent mitochondrial fission.
Free Radic Biol Med
; 221: 111-124, 2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38763207