1.
J Am Chem Soc
; 136(44): 15469-72, 2014 Nov 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-25308898
RESUMEN
A novel Pd(0)-catalyzed intramolecular arylative dearomatization of para-aminophenol derivatives is described. In the presence of 1.25 mol % [Pd(C3H5)Cl]2 and 3.75 mol % RuPhos, the arylative dearomatization reaction proceeds smoothly for a broad range of substrates, offering an efficient synthetic route to erythrinane derivatives in excellent yields.
Asunto(s)
Aminofenoles/química , Paladio/química , Catálisis
2.
Org Lett
; 10(10): 2031-4, 2008 May 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-18422288
RESUMEN
Asymmetric synthesis of trans-alkenyl alpha-amino esters was realized by chiral phosphoric acid catalyzed transfer hydrogenation of beta,gamma-alkynyl alpha-imino esters. Utilizing Hantzsch esters as the hydrogen donor, both the alkyne and imine moieties of beta,gamma-alkynyl alpha-imino esters were reduced to afford trans-alkenyl alpha-amino esters with up to 96% ee.
Asunto(s)
Ésteres/síntesis química , Iminoácidos/síntesis química , Ácidos Fosfóricos/química , Catálisis , Ésteres/química , Hidrogenación , Iminoácidos/química , Estructura Molecular , Oxidación-Reducción
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