[Comprehensive laboratory diagnosis of intravascular blood coagulation syndrome in late gestosis]. / Kompleksnaia laboratornaia diagnostika sindroma vnutrisosudistogo svertyvaniia krovi pri pozdnykh gestozakh.

A chronic form of intravascular blood coagulation (the DIC syndrome) is an obligatory pathogenetic mechanism in the organism of pregnant women with late gestoses. In order to find the DIC-syndrome and to provide urgent protective measures comprehensive laboratory diagnostics of the hemostatic pathologies is necessary. Analysis of clinician data has shown an optimal quantity and sequence of tests, among which some are traditional and several have been worked out by the authors. This approach can be recommended for corresponding medical institutions as such that provides obtaining exact and informative data about the state of blood coagulation with minimal amounts of human plasma.

[Pathomorphological changes in the uterine wall in gestosis]. / Patomorfologicheskie izmeneniia stenki matki pri gestoze.

With the purpose of studying a morphological substrate of the uterine contractile function disorder in gestosis, an investigation was conducted designed to study biopsy specimens of the uterine wall having been taken during the cesarean section in 80 parturient women. The womb of those parturient women having mild and severe gestosis complicated by uterine inertia (40 observations) or premature dethachement of the normally situated placenta (8 cases) was studied together with that of controls (32 cases). The indentified micro-circulatory disturbances and alterative changes in the myometrium structures in gestosis are regarded as one of the generalized blood circulation disorders, hemostasis (dissaminated intravascular blood coagulation) and systemic abnormalities of metabolism presenting as a multiorgan failure developing in the pathology under consideration. Microcirculatory disturbances and hypoxia-related dystrophic changes in the smooth myoblasts and connective tissue leading to its fibrosis--all these constitute a morphological substrate of changes in the contractile function of the womb.