Characterizing mid-infrared micro-ring resonator with frequency conversion.

Due to the high cost, low-performance lasers and detectors in the mid-infrared (MIR) band, the development of MIR-integrated devices is very slow. Here, we demonstrate an effective method to characterize the parameters of MIR devices by using frequency conversion technology. We designed and fabricated rib waveguides and the micro-ring resonators (MRRs) on a silicon-on-sapphire platform. The MIR laser for the test is generated by difference frequency generation, and the transmission spectrum of the MIR-MRRs is detected by sum frequency generation. The experimental results show that the waveguide transmission loss is 4.5 dB/cm and the quality factor of the micro-ring reaches 38000, which is in good agreement with the numerical simulations. This work provides a useful method to characterize MIR integrated devices based on the frequency conversion technique, which can boost the development of MIR integrated optics in the future.

Observing multiple processes of backward-phase-matching spontaneous parametric downconversion in a single-periodic crystal.

A nonlinear process based on backward quasi-phase matching (BQPM) can be used to realize mirrorless optical parametric oscillation, the generation of paired photons with a separable joint spectral amplitude and narrow wavelength bandwidth, and the preparation of counterpropagating polarization-entangled photons, which shows distinct advantages over some applications based on forward quasi-phase matching. In this work, three types of BQPM in a bulk periodically poled potassium titanyl phosphate crystal with a single period are theoretically analyzed. Experimentally, the harmonic wave generated by second-harmonic generation in type 0 and type I exhibits a narrow bandwidth of 15.5 GHz. Furthermore, photon pairs generated by spontaneous parametric downconversion in all types of BQPM (type 0, type I, and type II) at 7th order are observed and characterized. Their coincidence-to-accidental ratios are all greater than 5 × 103 in the pump power range from 10 mW to 500 mW. This research lays the foundation for further applications of BQPM in nonlinear optics, quantum optics, and quantum information processing.

Orelabrutinib-bruton tyrosine kinase inhibitor-based regimens in the treatment of central nervous system lymphoma: a retrospective study.

BACKGROUND: Central nervous system lymphoma (CNSL) is an aggressive lymphoma. Orelabrutinib, an oral Bruton tyrosine kinase inhibitor, is a new treatment strategy for CNSL. This study aims to evaluate the efficacy and safety of orelabrutinib-based regimens in the treatment of patients with CNSL. METHODS: Twenty-three patients with CNSL were included in this retrospective study. All patients received the orelabrutinib-based regimen. Efficacy was evaluated based on investigators' assessment of overall response rate (ORR), complete response/unconfirmed complete response (CR/CRu), partial response (PR), stable disease (SD), progressive disease (PD), duration of response (DOR), progression-free survival (PFS) and overall survival (OS). The safety of orelabrutinib-based regimens has also been evaluated. RESULTS: A total of 17.39% of patients received orelabrutinib-based regimens for consolidation therapy, and 82.61% of patients for induction therapy (4 newly diagnosed CNSL, 15 relapsed/refractory CNSL). In the newly diagnosed CNSL group, the ORR was 100% (1 CR, 1 CRu, 2 PR). The 6-month DOR rate, 6-month PFS rate, and 6-month OS rate were 100%, 100%, and 100%, respectively. Of the 15 relapsed/refractory CNSL patients, five therapy regimens were applied (orelabrutinib, n = 3; orelabrutinib/immunotherapy, n = 3; orelabrutinib/chemotherapy, n = 2; orelabrutinib/immunochemotherapy, n = 6; orelabrutinib/radiotherapy, n = 1). The ORR was 60.00% (4 CR, 5 PR). The 6-month DOR rate, 6-month PFS rate, and 6-month OS rate were 92.30%, 67.70%, and 70.00%, respectively. Twenty-one patients reported adverse events (AEs), and 6 patients experienced grade ≥ 3 AEs. CONCLUSION: Orelabrutinib-based regimens were efficacious and well-tolerated in patients with CNSL. These combined therapies offer a new potential therapeutic strategy for patients with CNSL.

Measuring the tuning curve of spontaneous parameter downconversion using a comet-tail-like pattern.

Comet-tail-like interference patterns are observed using photons from the spontaneous parametric downconversion (SPDC) process. The patterns are caused by the angular-spectrum-dependent interference and the diffraction of a blazed grating. We present a theoretical explanation and simulation results for these patterns, which are in good agreement with the experimental results. The most significant feature of the patterns is the bright parabolic contour profile, from which one can deduce the parameter of the parabolic tuning curve of the SPDC process. This method could be helpful when designing experiments based on SPDC.

Interference fringes in a nonlinear Michelson interferometer based on spontaneous parametric down-conversion.

Quantum nonlinear interferometers (QNIs) can measure the infrared physical quantities of a sample by detecting visible photons. A QNI with Michelson geometry based on the spontaneous parametric down-conversion in a second-order nonlinear crystal is studied systematically. A simplified theoretical model of the QNI is presented. The interference visibility, coherence length, equal-inclination interference, and equal-thickness interference for the QNI are demonstrated theoretically and experimentally. As an application example of the QNI, the refractive index and the angle between two surfaces of a BBO crystal are measured using equal-inclination interference and equal-thickness interference.

Fourth-harmonic generation of orbital angular momentum light with cascaded quasi-phase matching crystals.

Orbital angular momentum (OAM) light, combined with the nonlinear process to expand the frequency range, has drawn increasing research interest in recent years. Here, we implement the first, to the best of our knowledge, experimental fourth-harmonic generation of OAM light with two cascaded quasi-phase-matching crystals. A Laguerre-Gaussian beam was transmitted through a duplet crystals system and frequency-doubled twice by two separate second-harmonic generation processes, which transduced the frequency of the OAM beam from telecom band to visible band and then to ultraviolet (UV) band. The topological charge of the OAM beam was increased substantially in the cascaded frequency conversion processes. In this experiment, we verify the OAM conservation by utilizing a specially designed interferometer, and the results correspond well with the numerical simulation. This work provides an effective method for the generation of UV OAM beams with high topological charges.

Real-time quantum edge enhanced imaging.

With the development of optical information processing technology, image edge enhancement technology has rapidly received extensive attention, especially in the field of quantum imaging. However, quantum edge enhanced imaging faces challenges in terms of time-consuming acquisition processes and the complexity of the devices used, which limits practical applications in real-time usage scenarios. Here we introduce and experimentally demonstrate a real-time (0.5 Hz) quantum edge enhanced imaging method that combines the spiral phase contrast technique with heralded single-photon imaging. The edge enhancement results show high quality and background free from raw data. Compared with direct imaging, our configuration can improve the signal-to-noise ratio significantly using the tight time correlations between photon pairs. The method also offers competitive advantages over ghost imaging, including higher brightness and a compact optical fiber delay rather than a free space delay. Additionally, we explore curved edge enhancement for specific feature recognition and the oriented shadow effect. Overall, this efficient and versatile platform paves an alternative path toward real-time quantum edge detection in applications including nondestructive bio-imaging, night vision and covert monitoring.

High-quality versatile photonic sources for multiple quantum optical experiments.

Entangled sources are important components for quantum information science and technology (QIST). The ability to generate high-quality entangled sources will determine the extent of progress in this field. Unlike previous schemes, a thin quasi-phase matching nonlinear crystal and a dense-wave-division-multiplexing device are used here to build high-quality versatile photonic sources with a simple configuration that can be used to perform Hong-Ou-Mandel interference, time-energy entanglement and multi-channel polarization entanglement experiments. The measurement results from various quantum optical experiments show the high quality of these photonic sources. These multi-functional photonic sources will be very useful in a variety of QIST applications.

Nonlinear frequency conversion and manipulation of vector beams in a Sagnac loop.

Vector beams (VBs) are widely investigated for their special intensities and polarization distributions, which are useful in optical micromanipulation, optical microfabrication, optical communication, and single molecule imaging. To date, nonlinear frequency conversion (NFC) and manipulation of VBs remain challenging because of the polarization sensitivity of most nonlinear processes. Here we report an experimental realization of NFC and manipulation of VBs that can be used to expand the available frequency band. The main idea of our scheme is the introduction of a Sagnac loop to solve the polarization dependence problem of NFC in nonlinear crystals. Additionally, we find that a linearly polarized VB should be transformed into a hybrid-polarized VB in exponential form before performing NFC. The experimental results agree well with those of our theoretical model. The proposed method is also applicable to other wavebands and second-order nonlinear processes, and may be generalized to the quantum regime for single photons.

On-chip generation of time-and wavelength-division multiplexed multiple time-bin entanglement.

Optical quantum states based on entangled photons are the key resource in quantum-information science. The realization of multiplexed multiple entanglement are necessary for developing high-capacity quantum information process. Silicon-on-insulator (SOI) has recently become a leading platform for generating and processing of non-classical optical states. In this work, by combining the wavelength- and time-division multiplexing technologies, we demonstrate a multiplexing time-bin entangled photon pair source based on a silicon nanowire waveguide and distribute entangled photons into 3(time) × 14(wavelength) channels independently. The indistinguishability of photon pairs in each time channel is confirmed by a fourfold Hong-Ou-Mandal quantum interference. Our work paves a new and promising way to achieve a high capacity quantum communication and to generate a multiple-photon non-classical state.

Quantum frequency conversion for multiplexed entangled states generated from micro-ring silicon chip.

Silicon-on-chip photonic circuits are among some very promising platforms for generating nonclassical photonic quantum state, because of its low loss, small footprint, and compatibility with complementary metal-oxide-semiconductor (CMOS) and telecommunications techniques. Dense wavelength division multiplexing (DWDM) is a leading technique for enhancing the transmission capacity of both classical and quantum communications. To bridge the frequency gap between silicon-chip and other quantum systems, such as quantum memories, a quantum interface is indispensable. Here, we demonstrate a quantum interface for multiplexed energy-time entanglement states, which are generated on a silicon micro-ring cavity that is based on frequency up-conversion. By switching the pump wavelength, energy-time entanglement from any channel can be selected at will after being up-converted. The high visibilities of two-photon interference over three channels after frequency up-conversion clearly prove that the entanglement is fully preserved during the quantum frequency conversion (QFC) process. Our work provides new perspectives regarding channel capacity enhancement in quantum communications and for quantum resources being transferred between two different quantum systems.

Revealing the Behavior of Photons in a Birefringent Interferometer.

The interferometer is one of the most important devices for revealing the nature of light and for precision optical metrology. Although many experiments were performed for probing photon behavior in various configurations, a complete study of photon behavior in a birefringent interferometer has not been performed, to our knowledge. By using an environmental turbulence immune Mach-Zehnder interferometer, we observe tunable photonic beatings by rotating a birefringent crystal versus the temperature of the crystal for both the single photon and two photons. Furthermore, the two-photon interference fringes beat 2 times faster than the single-photon interference fringes. This beating effect is used to determine the thermal dispersion coefficients of the two principal refractive axes with a single measurement: the two-photon interference shows superresolution and high sensitivity. Obvious differences between two-photon and single-photon interference are also revealed in unbalanced situations. In addition, the influence of the photon bandwidth on the beating behaviors that come from polarization-dependent decoherence is also investigated. Our findings will be important for better understanding the behavior of two-photon interference in a birefringent interferometer and for precision optical metrology with quantum enhancement.

Coherent frequency bridge between visible and telecommunications band for vortex light.

In quantum communications, vortex photons can encode higher-dimensional quantum states and build high-dimensional communication networks (HDCNs). The interfaces that connect different wavelengths are significant in HDCNs. We construct a coherent orbital angular momentum (OAM) frequency bridge via difference frequency conversion in a nonlinear bulk crystal for HDCNs. Using a single resonant cavity, maximum quantum conversion efficiencies from visible to infrared are 36%, 15%, and 7.8% for topological charges of 0,1, and 2, respectively. The average fidelity obtained using quantum state tomography for the down-converted infrared OAM-state of topological charge 1 is 96.51%. We also prove that the OAM is conserved in this process by measuring visible and infrared interference patterns. This coherent OAM frequency-down conversion bridge represents a basis for an interface between two high-dimensional quantum systems operating with different spectra.

Two-color hyper-entangled photon pairs generation in a cold 85Rb atomic ensemble.

Hyper-entangled photon pairs are very promising in the quantum information field for enhancing the channel capacity in communication and improving compatibility for networks. Here we report on the experimental generation of a hyper-entangled photon pair at a wavelength of 795 nm and 1475 nm via the spontaneous four-wave mixing process in a cold 85Rb atomic ensemble. The photons in each pair generated are entangled in both the time-frequency and polarization degrees of freedom. Such hyper-entangled photon pairs with special wavelength have potential applications in high-dimensional quantum communication and quantum physics.

Transcoder for the spatial and temporal modes of a photon.

Encoding information in light with orbital angular momentum (OAM) enables networks to increase channel capacity significantly. However, light in only the fundamental Gaussian mode is suitable for fibre transmission, and not higher order Laguerre Gaussian modes, which carry OAM. Therefore, building a bridge to interface light with OAM and Gaussian mode time-binning is crucially important. Here, we report the realization of a photonic transcoder, by which light with an arbitrary OAM superposition is experimentally converted into a time-bin Gaussian pulse, and vice versa. Furthermore, we clearly demonstrate that coherence is well conserved and there is no cross-talk between orthogonal modes. This photonic device is simple and can be built with scalable architecture. Our experimental demonstration paves the way towards a mixed optical communication in free-space and optical fibre.

Non-destructive splitter of twisted light based on modes splitting in a ring cavity.

Efficiently discriminating beams carrying different orbital angular momentum (OAM) is of fundamental importance for various applications including high capacity optical communication and quantum information processing. We design and experimentally verify a distinguished method for effectively splitting different OAM-carried beams by introducing Dove prisms in a ring cavity. Because of rotational symmetry broken of two OAM-carried beams with opposite topological charges, their transmission spectra will split. When mode and impedance matches between the cavity and one OAM-carried beam are achieved, this beam will transmit through the cavity and other beam will be reflected, both beams keep their spatial shapes. In this case, the cavity acts like a polarized beam splitter. Besides, the transmitting beam can be selected at your will, the splitting efficiency can reach unity if the cavity is lossless and it completely matches the beam. Furthermore, beams carry multi-OAMs can also be split by cascading ring cavities.

Orbital Angular Momentum-Entanglement Frequency Transducer.

Entanglement is a vital resource for realizing many tasks such as teleportation, secure key distribution, metrology, and quantum computations. To effectively build entanglement between different quantum systems and share information between them, a frequency transducer to convert between quantum states of different wavelengths while retaining its quantum features is indispensable. Information encoded in the photon's orbital angular momentum (OAM) degrees of freedom is preferred in harnessing the information-carrying capacity of a single photon because of its unlimited dimensions. A quantum transducer, which operates at wavelengths from 1558.3 to 525 nm for OAM qubits, OAM-polarization hybrid-entangled states, and OAM-entangled states, is reported for the first time. Nonclassical properties and entanglements are demonstrated following the conversion process by performing quantum tomography, interference, and Bell inequality measurements. Our results demonstrate the capability to create an entanglement link between different quantum systems operating in a photon's OAM degrees of freedom, which will be of great importance in building a high-capacity OAM quantum network.

CW-pumped telecom band polarization entangled photon pair generation in a Sagnac interferometer.

Polarization entangled photon pair source is widely used in many quantum information processing applications such as teleportation, quantum communications, quantum computation and high precision quantum metrology. We report on the generation of a continuous-wave pumped 1550 nm polarization entangled photon pair source at telecom wavelength using a type-II periodically poled KTiOPO(4) (PPKTP) crystal in a Sagnac interferometer. Hong-Ou-Mandel (HOM) interference measurement yields signal and idler photon bandwidth of 2.4 nm. High quality of entanglement is verified by various kinds of measurements, for example two-photon interference fringes, Bell inequality and quantum states tomography. The source can be tuned over a broad range against temperature or pump power without loss of visibilities. This source will be used in our future experiments such as generation of orbital angular momentum entangled source at telecom wavelength for quantum frequency up-conversion, entanglement based quantum key distributions and many other quantum optics experiments at telecom wavelengths.

Classical to quantum optical network link for orbital angular momentum-carrying light.

Using orbital angular momentum (OAM) conservation in second-order nonlinear interaction processes, we create a classical to quantum optical network link in the OAM degrees of freedom of light via sum frequency generation, followed by spontaneous parametric down-conversion. Coherent OAM-carrying beams at 1550 nm are up-converted to 525.5-nm OAM-carrying beams in the first crystal, and are used to pump a second crystal to generate non-degenerate OAM entangled photon pairs at 795 nm and 1550 nm. By switching the OAM carried by the classical part, OAM correlation in the quantum part is shifted. High-level OAM entanglements in two-dimensional subspaces are verified.

Optical precursor with four-wave mixing and storage based on a cold-atom ensemble.

We observed optical precursors in four-wave mixing based on a cold-atom gas. Optical precursors appear at the edges of pulses of the generated optical field, and propagate through the atomic medium without absorption. Theoretical analysis suggests that these precursors correspond to high-frequency components of the signal pulse, which means the atoms cannot respond quickly to rapid changes in the electromagnetic field. In contrast, the low-frequency signal components are absorbed by the atoms during transmission. We also showed experimentally that the backward precursor can be stored using a Raman transition of the atomic ensemble and retrieved later.