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Carbohydr Polym ; 241: 115260, 2020 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-32507221

RESUMEN

This study presents a green synthesis route to silver nanoparticles (AgNPs) stabilized with cashew gum (CG) or carboxymethylated cashew gum (CCG) using microwave-assisted synthesis and evaluates their antibacterial activity. The antimicrobial activity was measured by determining the minimum inhibitory concentration (MIC) with Staphylococcus aureus and Escherichia coli. In both cases of the presence of CG and CCG, it was found that higher pH lead to more efficient conversion of silver nitrate to AgNPs with well dispersed, spherical and stable particles as well as low crystallinity. CCG-capped AgNPs were slightly smaller (137.0 and 96.3 nm) than those coated with non-modified gum (144.7 and 100.9 nm). The samples presented promising antibacterial activity, especially on Gram-negative bacteria, resulting in significant membrane damage on treated bacteria in comparison to the untreated control, observed by atomic force microscopy. Thus, a quick and efficient synthesis route was applied to produce CGAgNPs and CCGAgNPs with antimicrobial potential.


Asunto(s)
Anacardium , Antibacterianos , Nanopartículas del Metal , Gomas de Plantas , Plata , Antibacterianos/administración & dosificación , Antibacterianos/química , Escherichia coli/efectos de los fármacos , Escherichia coli/crecimiento & desarrollo , Nanopartículas del Metal/administración & dosificación , Nanopartículas del Metal/química , Pruebas de Sensibilidad Microbiana , Microondas , Gomas de Plantas/administración & dosificación , Gomas de Plantas/química , Plata/administración & dosificación , Plata/química , Staphylococcus aureus/efectos de los fármacos , Staphylococcus aureus/crecimiento & desarrollo
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