RESUMEN
BACKGROUND: Risk-reducing operations are an important part of the management of hereditary predisposition to cancer. In selected cases, they can considerably reduce the morbidity and mortality associated with cancer in this population. OBJECTIVES: The Brazilian Society of Surgical Oncology (BSSO) developed this guideline to establish national benchmarks for cancer risk-reducing operations. METHODS: The guideline was prepared from May to December 2021 by a multidisciplinary team of experts to discuss the surgical management of cancer predisposition syndromes. Fourteen questions were defined and assigned to expert groups that reviewed the literature and drafted preliminary recommendations. Following a review by the coordinators and a second review by all participants, the groups made final adjustments, classified the level of evidence, and voted on the recommendations. RESULTS: For all questions including risk-reduction bilateral salpingo-oophorectomy, hysterectomy, and mastectomy, major agreement was achieved by the participants, always using accessible alternatives. CONCLUSION: This and its accompanying article represent the first guideline in cancer risk reduction surgery developed by the BSSO, and it should serve as an important reference for the management of families with cancer predisposition.
Asunto(s)
Neoplasias de la Mama , Ginecología , Neoplasias Ováricas , Oncología Quirúrgica , Brasil/epidemiología , Neoplasias de la Mama/genética , Neoplasias de la Mama/prevención & control , Neoplasias de la Mama/cirugía , Femenino , Humanos , Mastectomía , Neoplasias Ováricas/cirugíaRESUMEN
Breast cancer is the most common malignant neoplasm diagnosed during pregnancy. Metaplastic carcinoma is a rare type of breast cancer, representing 1.5% out of all kinds. This is a case report of metaplastic carcinoma in a pregnant woman aged 39 years
O câncer de mama é a neoplasia maligna mais comumente diagnosticado durante a gestação. O carcinoma metaplásico é um tipo raro de câncer mamário que representa 1,5% de todos os tipos. A seguir, é relatado um caso de carcinoma metaplásico em gestante de 39 anos.