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1.
Br J Nutr ; 129(1): 166-174, 2023 01 14.
Artículo en Inglés | MEDLINE | ID: mdl-35264258

RESUMEN

Mounting evidence suggests that the first few months of life are critical for the development of obesity. The relationships between the timing of solid food introduction and the risk of childhood obesity have been examined previously; however, evidence for the association of timing of infant formula introduction remains scarce. This study aimed to examine whether the timing of infant formula introduction is associated with growth z-scores and overweight at ages 1 and 3 years. This study included 5733 full-term (≥ 37 gestational weeks) and normal birth weight (≥ 2500 and < 4000 g) children in the Born in Guangzhou Cohort Study, a prospective cohort study with data collected at 6 weeks, 6, 12 and 36 months. Compared with infant formula introduction at 0-3 months, introduction at 4-6 months was associated with the lower BMI, weight-for-age and weight-for-length z-scores at 1 and 3 years old. Also, introduction at 4-6 months was associated with the lower odds of at-risk of overweight at age 1 (adjusted OR 0·72, 95 % CI 0·55, 0·94) and 3 years (adjusted OR 0·50, 95 % CI 0·30, 0·85). Introduction at 4-6 months also decreased the odds of overweight at age 1 year (adjusted OR 0·42, 95 % CI 0·21, 0·84) but not at age 3 years. Based on our findings, compared with introduction within the first 3 months, introduction at 4-6 months has a reduction on later high BMI risk and at-risk of overweight. However, these results need to be replicated in other well-designed studies before more firm recommendations can be made.


Asunto(s)
Sobrepeso , Obesidad Infantil , Lactante , Femenino , Humanos , Niño , Preescolar , Sobrepeso/epidemiología , Estudios de Cohortes , Obesidad Infantil/epidemiología , Obesidad Infantil/prevención & control , Fórmulas Infantiles , Índice de Masa Corporal , Estudios Prospectivos , Lactancia Materna
2.
Colorectal Dis ; 25(11): 2206-2216, 2023 11.
Artículo en Inglés | MEDLINE | ID: mdl-37787161

RESUMEN

AIM: No studies have compared the clinical outcomes of early and delayed feeding in patients with acute lower gastrointestinal bleeding (ALGIB). This study aimed to evaluate the benefits and risks of early feeding in a nationwide cohort of patients with ALGIB in whom haemostasis was achieved. METHODS: We reviewed data for 5910 patients with ALGIB in whom haemostasis was achieved and feeding was resumed within 3 days after colonoscopy at 49 hospitals across Japan (CODE BLUE-J Study). Patients were divided into an early feeding group (≤1 day, n = 3324) and a delayed feeding group (2-3 days, n = 2586). Clinical outcomes were compared between the groups by propensity matching analysis of 1508 pairs. RESULTS: There was no significant difference between the early and delayed feeding groups in the rebleeding rate within 7 days after colonoscopy (9.4% vs. 8.0%; p = 0.196) or in the rebleeding rate within 30 days (11.4% vs. 11.5%; p = 0.909). There was also no significant between-group difference in the need for interventional radiology or surgery or in mortality. However, the median length of hospital stay after colonoscopy was significantly shorter in the early feeding group (5 vs. 7 days; p < 0.001). These results were unchanged when subgroups of presumptive and definitive colonic diverticular bleeding were compared. CONCLUSION: The findings of this nationwide study suggest that early feeding after haemostasis can shorten the hospital stay in patients with ALGIB without increasing the risk of rebleeding.


Asunto(s)
Colonoscopía , Hemorragia Gastrointestinal , Humanos , Tiempo de Internación , Hemorragia Gastrointestinal/etiología , Hemorragia Gastrointestinal/terapia , Colonoscopía/métodos , Enfermedad Aguda , Estudios de Cohortes , Estudios Retrospectivos , Estudios Multicéntricos como Asunto
3.
Anim Biotechnol ; 34(7): 2855-2862, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36169056

RESUMEN

The present study aimed to investigate the effect of early access to feed and water post-hatch on broiler chicks' performance. One hundred and twenty chicks were transferred from the hatchery to the rearing house and randomly divided into two groups. The first group: chicks were immediately access to feed and water (F-time 0). The second group: was held without feed and water for 24 h (F-time 24). Then, feed and water were provided ad-libitum, for both groups until 35 days of age. Results indicated that F-time 0 increased body weight and body weight gain throughout the experimental period. It increased feed intake during all experimental periods except from (22-28 days). Additionally, the F-time 0 enhanced the European production efficiency factor index. The F-time 24, increased red blood cells (RBCs) count, hemoglobin (HGB), and packed cell volume (PCV) percentage after 24 h. However, the F-time 0 had a higher RBCs count, HGB, and PCV at 35 days of age. F-time 24 increased total plasma protein, albumin, cholesterol, and triglycerides, after 24 h. In conclusion, early access to feed and water post-hatch enhances broiler chicks' performance and productivity and increases producers' revenue.


Asunto(s)
Pollos , Ingestión de Alimentos , Animales , Aumento de Peso , Agua , Alimentación Animal/análisis
4.
J Indian Assoc Pediatr Surg ; 28(4): 319-324, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37635895

RESUMEN

Aim: Enhanced recovery after surgery (ERAS) are multimodal perioperative pathways that have shown improved outcomes. ERAS after colostomy reversal has shown promising results in adults and few pediatric studies. We report our experience using ERAS for a colostomy reversal. Materials and Methods: A retrospective analysis of children in whom ERAS was used during colostomy reversal between May 2016 and 2019 was carried out. ERAS protocol in our study included avoiding mechanical bowel preparation (MBP), oral liquid diet upto 3 h preoperatively, usage of regional anesthesia, minimal handling of bowel intraoperatively, using nonopioid analgesics for pain relief, early initiation of feeding on the first postoperative day, early discharge once full feeds are established. Outcomes analyzed are the duration of hospital stay and complications, including readmissions. Requirement for opioids and anti-emetics are noted. The outcomes are compared with traditional care pathways (TCP), which use MBP, overnight fasting, opioid analgesia, and delayed feeding. A total of 48 are included in the study, with 13 cases using ERAS and TCP in 35 cases. Statistical Analysis Used: Nonparametric Mann-Whitney U-test was used. Results: In the ERAS group, the mean length of hospital stay (LOS) postoperatively was 3.7 days (2-5 days) as opposed to 7.2 days (5-11 days) in TCP. There was only one child with complications in the ERAS group, while 9 cases in TCP had complications, though none of them required operative intervention. There was the requirement of anti-emetic in only one child in the ERAS group. Conclusion: ERAS for colostomy reversal is feasible in the pediatric population. For successful implementation, all personnel involved in the care of the child need to be educated about the protocol. It reduces LOS and complications.

5.
J Indian Assoc Pediatr Surg ; 28(5): 392-396, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37842224

RESUMEN

Background: Conventionally, oral feeds after distal bowel anastomosis surgery (ileostomy/colostomy closure) are delayed until after bowel peristalsis is established. The safety of an early feeding regimen is not established in children. This study compared early feeding regimens with delayed feeding in children undergoing elective intestinal anastomosis surgeries. Materials and Methods: In this retrospective multicentric cohort study, children undergoing elective distal bowel anastomosis surgery were divided into Group A (oral feeds allowed within 6 h) and Group B (delayed feeds). The two groups were compared for the incidence of abdomen distension, vomiting, surgical site infection, duration of analgesia, length of hospital stay, and readmission rate. Results: During the study, 58 patients were included: Group A (n = 26) and Group B (n = 32). The duration of analgesia (1.9 vs. 4.01 days) and length of hospital stay (3.38 vs. 5.0 days) were significantly less in Group A. Abdominal distension (7.7% vs. 15.6%), vomiting (11.5% vs. 15.6%), surgical site infection rate (3.8% vs. 12.5%), and readmissions (0% vs. 3.1%) were less in Group A, but statistically not significant. Conclusion: Early feeding after the elective restoration of distal bowel continuity can be safely practiced in the pediatric population. It is associated with a reduced need for analgesia and shorter hospital stay.

6.
BMC Pediatr ; 22(1): 609, 2022 10 20.
Artículo en Inglés | MEDLINE | ID: mdl-36266622

RESUMEN

BACKGROUND: Feeding practices during early years may have long-lasting influences on eating behaviors, growth patterns and body mass index (BMI) trajectory. The objectives of this study were to characterize early feeding practices among mothers in Saudi Arabia and examine their associations with child birthweight and BMI z-score (BMIz) at preschool. METHODS: This is a cross-sectional study including 209 mother-child dyads who were recruited from different preschools around the city of Jeddah, Saudi Arabia. Mothers completed the study questionnaire over the telephone and preschoolers' anthropometric measurements were objectively measured using standardized procedures. Primary predictors included variables pertaining to breastfeeding initiation, breastfeeding duration, formula milk introduction, complementary feeding, and offering fruit juice, date syrup-milk mixture, and soda drinks in a baby bottle. The study's primary outcome was BMIz at preschool. Mothers reported child's birthweight and sociodemographic characteristics. Descriptive statistics were used to characterize early feeding practices. Bivariate analyses and linear regression analysis were used to examine the association of early feeding practices with child birthweight and BMIz at preschool. RESULTS: About half of the mothers reported that they have offered fruit juice and/or date syrup-milk mixture in a baby bottle (52.2% and 45.9% respectively), with an average duration of 11.5 months (SD = 7.73) and 5.90 months (SD = 6.13), respectively. Children who were offered fruit juice and/or date syrup-milk mixture in a baby bottle had significantly lower birthweights compared to children who were not (M = 2.79, SD = 0.59 vs. M = 3.06, SD = 0.69, P < 0.01 and M = 2.79, SD = 0.67 vs. M = 3.03, SD = 0.62, P < 0.01, respectively). There was a negative association between introducing fruit juice in a baby bottle and child BMIz at preschool (ß: -0.18, 95% confidence interval (CI): -0.83, -0.11); This association was not significant after adjusting for child birthweight and other covariates (ß: -0.10, 95% CI: -0.64, 0.09). CONCLUSION: A large proportion of mothers reported offering fruit juice and date syrup-milk mixture in a baby bottle. Additional research is needed to understand associations with child birthweight and BMIz. Longitudinal and interventions studies can help inform counseling guidelines and community campaigns in order to improve early feeding practices in the region.


Asunto(s)
Lactancia Materna , Conducta Alimentaria , Femenino , Preescolar , Humanos , Índice de Masa Corporal , Estudios Transversales , Peso al Nacer , Arabia Saudita , Conducta Alimentaria/psicología , Madres/psicología
7.
Dysphagia ; 37(5): 1137-1141, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-34647150

RESUMEN

Despite recent advances in the radiation techniques used for the treatment of head and neck cancer (HNC) including intensity-modulated radiotherapy (IMRT), mandibular osteoradionecrosis (ORN) remains a significant complication. Advanced stage ORN is managed surgically with resection and immediate free tissue transfer reconstruction. An evaluation of the functional speech and swallowing outcomes was undertaken for patients undergoing surgical management of advanced ORN. We retrospectively reviewed consecutive patients, at a single, tertiary cancer centre, who underwent surgical resection for advanced Notani grade III ORN. Outcomes investigated included use and duration of tracheostomy and swallowing and speech status using Performance Status Scale for Head and Neck Cancer Normalcy of Diet (PSS-NOD) and Understandability of Speech (PSS-Speech) at baseline and 3 months following surgery. Ten patients underwent surgical resection with free tissue transfer reconstruction between January 2014 and December 2019. Two patients required supplemental nutrition via a gastrostomy at three months post surgery. As per the PSS-NOD data half of the patients' (n = 5) diet remained stable (n = 2) or improved (n = 3) and half of the participants experienced a decline in diet (n = 5). The majority of patients had no speech difficulties at baseline (n = 8). The majority of patients' speech remained stable (n = 8) with two patients experiencing a deterioration in speech clarity following surgery. Well-designed studies with robust, sensitive multidimensional dysphagia and communication assessments are required to fully understand the impact of surgical management of advanced ORN using resection with free tissue transfer reconstruction.


Asunto(s)
Neoplasias de Cabeza y Cuello , Enfermedades Mandibulares , Osteorradionecrosis , Deglución , Neoplasias de Cabeza y Cuello/complicaciones , Neoplasias de Cabeza y Cuello/radioterapia , Neoplasias de Cabeza y Cuello/cirugía , Humanos , Mandíbula , Enfermedades Mandibulares/complicaciones , Enfermedades Mandibulares/cirugía , Osteorradionecrosis/etiología , Osteorradionecrosis/cirugía , Estudios Retrospectivos , Resultado del Tratamiento
8.
Dysphagia ; 37(4): 1008-1013, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-34559292

RESUMEN

Traditionally patients can remain nil by mouth (NBM) for up to 12 days after oral tumour resection with free flap reconstruction to reduce the risk of flap dehiscence, poor healing and fistulae. The literature reports that patients could on average remain an inpatient for up to 20 days post-surgery. An evaluation of the impact of a defined early oral feeding protocol was undertaken investigating functional outcomes and complications rates. We prospectively reviewed tracheostomy use, length of hospital stay, non-oral feeding status and swallowing function using the Performance Status Scale for Head and Neck Cancer (PSS-HN) within a defined early feeding protocol. Twenty-nine patients underwent surgical resection with free flap reconstruction for advanced primary oral cancer between January 2018 and December 2019. Average age was 59.5 (range 24-88). Tumour sites included oral tongue (n = 10), maxilla (n = 6), mandible (n = 6), floor of mouth (n = 5) and buccal mucosa (n = 2). Median time to decannulation was 7 days (range 3-20 days, n = 11). The majority of patients were able to tolerate at least oral fluids on day 1 post-operatively (86%, n = 25). In addition to oral intake, non-oral feeding was required in 90% (n = 26), the majority of which included a nasogastric tube (NGT) placed intraoperatively 54% (n = 14), others required gastrostomy 46% (n = 12). Median time to nasogastric tube removal was 6 days (range 3-15 days). Median length of hospital stay was 10 days (range 3-51). Mean PSS-Normalcy of Diet (NOD) score at point of hospital discharge was 36.55 (95% CI 30.9-42.2). Flap failure was noted in 3% (n = 1). The adoption of an early oral feeding protocol suggests that there is the potential for a shorter hospital stay and earlier swallowing rehabilitation.


Asunto(s)
Colgajos Tisulares Libres , Neoplasias de la Boca , Procedimientos de Cirugía Plástica , Colgajos Tisulares Libres/cirugía , Humanos , Persona de Mediana Edad , Neoplasias de la Boca/cirugía , Complicaciones Posoperatorias/etiología , Procedimientos de Cirugía Plástica/efectos adversos , Procedimientos de Cirugía Plástica/métodos , Estudios Retrospectivos , Resultado del Tratamiento
9.
Dysphagia ; 37(5): 1305-1313, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-34981254

RESUMEN

Infants with congenital diaphragmatic hernia (CDH) who require non-invasive positive pressure ventilation or high flow nasal cannula are at risk for aspiration and delayed initiation of oral feeding. We developed a dysphagia provider-led protocol that involved early consultation with an occupational therapist or speech/language pathologist and modified barium swallow study (MBSS) to assess for readiness for oral feeding initiation/advancement on non-invasive positive pressure ventilation. The objective of this study was to retrospectively compare this intervention cohort to a historical control cohort to evaluate the protocol's impact on the time to initiate oral feeding. We describe the development and implementation of the protocol, the MBSS findings of the intervention cohort, and compared the control (n = 64) and intervention (n = 37) cohorts using Fischer's exact test and Mann-Whitney test. We found that both cohorts had similar prenatal and neonatal characteristics including age at extubation. Significantly more infants in the intervention cohort were on non-invasive positive pressure ventilation or high flow nasal cannula at the time of oral feeding initiation (84% vs. 28%, p < 0.0001). None of the control cohort infants underwent MBSS while on respiratory support. Of the intervention cohort, 15 infants underwent a MBSS while on non-invasive positive pressure ventilation; 6 had no evidence of laryngeal penetration and/or aspiration during swallowing. Infants in the control cohort initiated oral feeds significantly sooner after extubation (6 versus 11 days, p = 0.001) and attained full oral feeds earlier (20 days versus 28 days, p = 0.02) than the intervention group. There was no difference in the rate of gastrostomy tube placement (38%). Appropriate monitoring by a dysphagia provider and evaluation with clinical and radiological means are crucial to determine the safety of initiating oral feeding in term infants with CDH. Continued surveillance is needed to determine the long-term impact on oral feeding progression in this population.


Asunto(s)
Trastornos de Deglución , Hernias Diafragmáticas Congénitas , Deglución , Trastornos de Deglución/epidemiología , Trastornos de Deglución/etiología , Trastornos de Deglución/terapia , Hernias Diafragmáticas Congénitas/complicaciones , Humanos , Lactante , Recién Nacido , Respiración con Presión Positiva/métodos , Estudios Retrospectivos
10.
Dig Endosc ; 34(3): 451-458, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34536972

RESUMEN

INTRODUCTION: Early feeding was previously considered to increase the risk of postprocedural bleeding. However, many trials have demonstrated the benefits of early feeding after therapeutic endoscopic procedures. We conducted a meta-analysis of randomized controlled trials to evaluate the safety and outcomes between early feeding and delayed feeding after therapeutic endoscopic procedures. METHODS: Medline (PubMed), Embase, Google Scholar, the Cochrane Library, and clinicaltrials.gov were searched to identify randomized controlled trials that met our inclusion criteria. The pooled data for the mortality rate, postprocedural bleeding rate, and length of hospital stay were analyzed. RESULTS: A total of seven trials consisting of 717 patients were reviewed. These seven trials examined various therapeutic endoscopic procedures. Three trials included patients undergoing endoscopic hemostasis for upper gastrointestinal bleeding, two included patients undergoing esophageal variceal ligation, and two included patients with gastric neoplasm treated with endoscopic submucosal dissection. Although no significant differences were observed in the postprocedural bleeding rate or the mortality rate between patients who received early feeding and those who received delayed feeding, early feeding resulted in shorter hospital stays (weighted mean difference -1.04, 95% confidence interval -1.45 to 0.63). CONCLUSION: Early feeding appears to be a safe management method for patients undergoing therapeutic endoscopic procedures. Therefore, we recommend early feeding for these patients.


Asunto(s)
Resección Endoscópica de la Mucosa , Hemostasis Endoscópica , Hemorragia Gastrointestinal/terapia , Humanos , Tiempo de Internación , Ensayos Clínicos Controlados Aleatorios como Asunto
11.
BMC Gastroenterol ; 21(1): 165, 2021 Apr 13.
Artículo en Inglés | MEDLINE | ID: mdl-33849434

RESUMEN

BACKGROUND: Amyand's hernia was an unusual condition defined by the presence of an appendix located in the inguinal hernia sac. Its prevalence was 1% of all inguinal hernia in children. The clinical manifestation of Amyand's hernia was depending on hernia's stage, an incarcerated hernia will present with an inguinal mass following by pain and motility disorder. It could lead to abdominal distention in the late stage. The common location of Amyand's hernia was on the right side, the left side was uncommon. Early feeding on infants could provoke symptoms of bowel obstruction (SBO). More than 76% of infants in Java, Indonesia was given banana as solid food in infants before six months old. There is a correlation between the early banana diet and SBO. Amyand's hernia could present as morbidity of early banana diet. CASE PRESENTATION: We describe a case of two months old infant present with an incarcerated left inguinal hernia and history of early banana diet that performed herniotomy procedure. During the operation, we found left-side incarcerated Amyand's hernia with appendicitis, excoriation caecum, and sticky banana mass. CONCLUSION: This case suggest the possibility of early feeding of banana diet may provoke incarceration of an inguinal hernia and if the incarcerated hernia content contains the appendix, then an Amyand's hernia.


Asunto(s)
Apéndice , Hernia Inguinal , Musa , Apéndice/cirugía , Niño , Dieta , Hernia Inguinal/complicaciones , Hernia Inguinal/cirugía , Humanos , Indonesia , Lactante
12.
Surg Endosc ; 34(12): 5583-5592, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-31932940

RESUMEN

BACKGROUND: Avoiding the use of nasogastric tubes (NGTs) is recommended after colorectal surgery but there is no consensus on intraoperative gastric decompression using NGTs during colorectal surgery. The objective was to assess the effect of avoiding insertion of NGTs during colorectal surgery for the recovery of gastrointestinal (GI) functions. METHOD: 1561 patients undergoing colorectal surgery, for whom information on NGT use was available, were included in this retrospective analysis and propensity score analysis of the prospective GRACE Audit database. Patients who did and did not have an NGT during surgery were compared. RESULTS: Among the study population of 1561 patients, 696 patients were matched to correct baseline differences between groups. The no-NGT group significantly improved GI motility impairment (e.g., less postoperative nausea [OR = 0.59; CI 95%: 0.42-0.84] and a better tolerance of early feeding [OR = 2.07; CI 95%: 1.33-3.22]). Such an association was also highlighted for reduced postoperative morbidity [OR = 0.60; CI 95%: 0.43-0.83], and especially pulmonary complications [OR = 0.08; CI 95%: 0.01-0.59], or parietal complications [OR = 0.29; CI 95%: 0.09-0.87]. The risk of postoperative ileus was not significantly reduced in the no-NGT group [OR = 0.67; CI 95%: 0.43-1.06]. CONCLUSION: No NGT insertion during colorectal surgery is safe and could improve postoperative GI function recovery.


Asunto(s)
Cirugía Colorrectal , Bases de Datos como Asunto , Intubación Gastrointestinal , Puntaje de Propensión , Femenino , Humanos , Intubación Gastrointestinal/efectos adversos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Complicaciones Posoperatorias/etiología , Periodo Posoperatorio , Recuperación de la Función , Estudios Retrospectivos , Resultado del Tratamiento
13.
Ann Nutr Metab ; 74 Suppl 2: 29-42, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31234189

RESUMEN

Feeding and parenting are inextricably linked. The complex bidirectional interactions between parent feeding practices and child eating behaviour shape the early feeding environment which in turn interacts with genetic predispositions to lay the foundation for life-long eating habits and health outcomes. Parent feeding and child (and parent) eating are central to the fabric of family life and are strongly rooted in culture and tradition. Yet, many parents experience stress and anxiety related to this ubiquitous parenting task and perceive their child as a "fussy eater" or a "difficult feeder." Parents commonly misinterpret heritable and developmentally "normal" child eating behaviour, such as food refusal, as cause for concern. In an effort to get their child to "eat well" they respond with coercive feeding practices, such as pressure, reward and restriction. Emotional feeding that uses food to comfort, distract, calm or shape behaviour is also common. Although well intentioned, these non-responsive, parent- rather than child-centred feeding practices are ineffective, even counterproductive. They teach children to eat for reasons unrelated to appetite and, hence, more than they need and fail to support development of healthy food preferences and appetite regulation. Early feeding interventions are needed that assist parents to understand normal child eating behaviour and promote responsive feeding practices and effective food parenting. The aim of this chapter is to review (1) "normal" eating behaviour of young children, (2) the range of feeding practices and strategies that parents use to respond to and try to shape these behaviours, (3) evidence for approaches to feeding young children that have potential to reduce conflict related to child feeding and promote life-long healthy eating patterns that are a key determinant of long-term health and well-being and (4) to provide an overview of an early feeding intervention, NOURISH, which demonstrated a positive impact on maternal feeding practices and potentially reduced parent anxiety and stress related to feeding.


Asunto(s)
Dieta Saludable , Familia , Felicidad , Bienestar del Lactante , Relaciones Padres-Hijo , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino
14.
Dig Endosc ; 31(6): 646-652, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31038792

RESUMEN

BACKGROUND AND AIM: Oral feeding following variceal ligation in cirrhotics is usually delayed due to fear of rebleeding. Solid diet is usually further delayed (until 72 h) despite lack of evidence. We aimed to compare the impact of early versus delayed feeding on rebleeding following variceal ligation. METHODS: This was a prospective randomized controlled trial including patients undergoing variceal ligation for active esophageal variceal bleeding. Patients were randomized into two groups. In the early-feeding group, liquid diet was given after 1 h following variceal ligation and a regular solid diet was resumed after 4 h. In the delayed-feeding group, patients fasted for the first 4 h after variceal ligation, liquid diet was given until 24 h, soft diet for the next 48 h and a regular solid diet after 72 h. RESULTS: There were 52 and 49 patients in the early and delayed feeding groups, respectively. Very early rebleeding rates [2 (3.84%) vs 1 (2.04%); P ≥ 0.99] and delayed rebleeding rates [2 (3.84%) vs 4 (8.16%); P = 0.75] were similar in both groups. Protein and calorie intake in the early-feeding group was significantly better and early infections in active bleeders were significantly lower compared to the delayed-feeding group. One-month mortality was similar in both groups [3 (5.76%) vs 4 (8.16%); P = 0.75]. CONCLUSION: Early feeding with a regular solid diet in conscious patients after successful variceal ligation for esophageal varices is safe, provides better nutrition and results in lower incidence of infections in bleeders compared to delayed feeding.


Asunto(s)
Nutrición Enteral/métodos , Várices Esofágicas y Gástricas/complicaciones , Gastroenterología , Hemorragia Gastrointestinal/terapia , Cirrosis Hepática/complicaciones , Ensayos Clínicos Controlados Aleatorios como Asunto , Sociedades Médicas , Congresos como Asunto , Endoscopía Gastrointestinal/métodos , Várices Esofágicas y Gástricas/diagnóstico , Várices Esofágicas y Gástricas/terapia , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/etiología , Humanos , Ligadura/métodos , Cirrosis Hepática/diagnóstico , Cirrosis Hepática/terapia , Tiempo de Tratamiento
15.
J Paediatr Child Health ; 54(5): 480-486, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29278447

RESUMEN

AIM: Although early enteral nutrition (EN) is strongly associated with lower mortality in critically ill children, there is no consensus on the definition of early EN. The aim of this study was to evaluate our current practice supplying EN and to identify factors that affect both the initiation of feeding within 24 h after paediatric intensive care unit (PICU) admission and the adequate supply of EN in the first 48 h after PICU admission in critically ill children. METHODS: We conducted a prospective, multicentre, observational study in nine PICUs in Turkey. Any kind of tube feeding commenced within 24 h of PICU admission was considered early initiated feeding (EIF). Patients who received more than 25% of the estimated energy requirement via enteral feeding within 48 h of PICU admission were considered to have early reached target EN (ERTEN). RESULTS: Feeding was initiated in 47.4% of patients within 24 h after PICU admission. In many patients, initiation of feeding seems to have been delayed without an evidence-based reason. ERTEN was achieved in 43 (45.3%) of 95 patients. Patients with EIF were significantly more likely to reach ERTEN. ERTEN was an independent significant predictor of mortality (P < 0.001), along with reached target enteral caloric intake on day 2 associated with decreased mortality. CONCLUSIONS: There is a substantial variability among clinicians' perceptions regarding indications for delay to initiate enteral feeding in critically ill children, especially after the first 6 h of PICU admission. ERTEN, but not EIF, is associated with a significantly lower mortality rate in critically ill children.


Asunto(s)
Cuidados Críticos/métodos , Enfermedad Crítica/terapia , Nutrición Enteral/métodos , Pautas de la Práctica en Medicina/estadística & datos numéricos , Adolescente , Niño , Preescolar , Cuidados Críticos/estadística & datos numéricos , Enfermedad Crítica/mortalidad , Nutrición Enteral/estadística & datos numéricos , Femenino , Humanos , Lactante , Unidades de Cuidado Intensivo Pediátrico , Modelos Logísticos , Masculino , Estudios Prospectivos , Factores de Tiempo , Resultado del Tratamiento , Turquía
16.
J Trop Pediatr ; 64(1): 4-14, 2018 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-28369652

RESUMEN

Background of the study: Enteral feeding in preterm neonates with intrauterine growth restriction (IUGR) and absent or reversed end diastolic flow (AREDF) on umbilical artery (UA) Doppler is delayed owing to an increased risk of necrotizing enterocolitis (NEC). Delaying enteral feeding with longer duration of parenteral nutrition (PN) carries an increased risk of sepsis. Objectives: To study early versus late feeding in preterm IUGR neonates for time required to attain sufficient feed volume to discontinue PN and increased risk of NEC or feed intolerance (FI). Design: Open-label randomized controlled trial. Setting: Tertiary care neonatal unit and fetal-maternal medicine unit in India. Participants: Preterm intrauterine growth restricted neonates' ≤32 weeks with AREDF on UA Doppler enrolled from 1 January 2014 to 31 July 2015. Intervention: Randomized to receive early or late feeding using mothers own or donor breast milk as per a feed initiation and advancement protocol. Primary outcome: Time in days required to attain sufficient feed volume allowing discontinuation of PN and incidence of NEC in neonates fed early versus late. Results: There were 77 eligible neonates. Sixty-two neonates were included and stratified as extreme preterm (27-29 weeks) (n = 20) and very preterm (30-32 weeks) (n = 42). Ten extreme preterm and 21 very preterm neonates were randomized to each early feeding and late feeding arm. There was a significantly faster attainment of sufficient feeds in the early feeding arm of both the stratified groups [extreme preterm: median 14 days (Interquartile range IQR: 12-15) compared with 18 days (IQR: 18-20), hazard ratio (HR): 1.59, 95% CI: 0.626-4.078; very preterm: 12 days (IQR: 10-14) as compared with 16 days (IQR 15-17), HR: 1.89, 95% CI: 1.011-3.555]. There was no difference in the incidence of NEC, FI and combined outcome of NEC and FI. Conclusion: Early feeding in preterm IUGR neonates with AREDF on antenatal UA Doppler allowed earlier discontinuation of PN, allowing birth weight to be regained earlier and did not increase the incidence of NEC and FI.


Asunto(s)
Nutrición Enteral/métodos , Retardo del Crecimiento Fetal/terapia , Nutrición Parenteral/métodos , Nutrición Enteral/efectos adversos , Enterocolitis Necrotizante/epidemiología , Femenino , Humanos , Incidencia , India , Recién Nacido , Recien Nacido Prematuro , Masculino , Leche Humana , Monitoreo Fisiológico/métodos , Embarazo , Factores de Tiempo , Ultrasonografía Prenatal , Arterias Umbilicales/diagnóstico por imagen
17.
J Anim Physiol Anim Nutr (Berl) ; 102(6): 1625-1633, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30238515

RESUMEN

The management practices implemented by the poultry sector as using some nutritional additives in the early stage of a bird's life can potentially detect other challenges to production development in the poultry farms. Many potential supplements can be included in the early feeding as which are added to drinking water. In this study, 180 1-day-old chicks were randomly distributed into six groups to investigate the use of some nutritional supplements in drinking water of growing turkeys during 1st month of age and their effect on growth performance, carcass traits, meat quality, leg problems, blood profile and oxidative status. Birds that were supplied with tap water were considered the control group (C), whereas the birds that received the 1st, 2nd, 3rd, 4th and 5th treatments (T1, T2, T3, T4 and T5, respectively) were supplied with drinking water containing 10% sugar syrup, molasses, lemon juice, skim milk and fresh egg albumin respectively. The different water additives significantly (p < 0.05) affected the body weight (BW) and body weight gain (BWG) at all studied ages except for the BW at 4 weeks old and BWG at 0-4 weeks old and 8-12 weeks old. Significant effects of the treatments on the feed consumption (FC) and feed conversion ratio (FCR) were not observed during the experiment, and the treatments did not cause significant differences (p < 0.05) in the carcass cut-up traits, bone measurements, body temperature, plumage conditions, mortality rates and blood parameters except for IgA (p = 0.043). The activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) was improved in the treatment groups with 10% molasses and lemon juice respectively. The total antioxidant capacity (T-AOC) and catalase (CAT) activities were enhanced in the treatments compared with the control group. The plasma malondialdehyde (MDA) levels were decreased with the sugar syrup, molasses and lemon juice treatments compared with those in the control and other groups. Supplementation of molasses or lemon juice to drinking water of turkeys during the 1st month of age resulted in a higher profit margin in comparison with the control group. The results showed that birds supplied with water containing 10% molasses or lemon juice during the growing period presented an improved growth performance, immune response, antioxidant status and economic efficiency.


Asunto(s)
Antioxidantes/metabolismo , Suplementos Dietéticos , Agua Potable , Pavos/crecimiento & desarrollo , Albúminas/administración & dosificación , Animales , Composición Corporal , Peso Corporal , Carbohidratos , Citrus , Leche , Melaza , Distribución Aleatoria , Aumento de Peso/efectos de los fármacos
18.
Encephale ; 44(1): 32-39, 2018 Feb.
Artículo en Francés | MEDLINE | ID: mdl-27742391

RESUMEN

INTRODUCTION: Interest in the study of early feeding disorders (FD) has steadily increased during recent decades. During this period, research described the importance of the transactional relationships and the complex interplay between caregiver and child over time. On the basis of the previous studies, our study tried to explore the associations between the characteristics of the parents and the temperamental characteristics of the infants with early FD. GOALS: A first aim of the present study was to show if parental perception of child temperament (including ability for arousal self-regulation) and parental characteristics (emotional and eating attitudes) are associated with early FD. A second aim was to identify emotional/behavioral difficulties in children with early FD by comparing children with a normal development and children with a diagnosed FD, and to investigate whether there are any correlations between parental emotional and feeding characteristics and a child's eating and emotional-behavioral development. A final aim was to explore if feeding conflict is bound to both infant ability for arousal self-regulatation and caregiver emotional status during meals. METHOD: Participants: 58 clinical dyads (children aged 1-36 months) and 60 in the control group participated in the study. The sample of 58 infants and young children and their parents was recruited in a pediatric hospital. They were compared to healthy children recruited in several nurseries. PROCEDURE: all parent-child pairs in the clinical sample were observed in a 20-minute video-recording during a meal using the procedure of the Chatoor Feeding Scale. After the videotaping, parents completed a battery of self-report questionnaires assessing their child's and their own psychological symptom status. MEASURES: Child's malnutrition assessment was based on the Waterlow criteria. The Child Behavior Checklist (CBCL 1½-5) was used to assess a child's emotional/behavioral functioning. The Infant Behavior Questionnaire-Revised (IBQ-R), a widely used parent-report measure of infant temperament, was used to identify the structure of infant temperament. The Eating Attitude Test-40, a self-report symptom inventory, was used to identify concerns with eating and weight in the adult population. The Chatoor Feeding Scale was used to assess mother-child feeding interactions during a meal based on the analysis of the videotaped feeding session. RESULTS: Analyses revealed that children with FD did not have a difficult temperament, especially no disability for arousal of self-regulatation, but their emotional-behavioral functioning is characterized by internalizing problems. Analyses of the EAT-40 showed that mothers of the children diagnosed with FD had significantly higher scores than mothers of the control sample; it means these mothers showed more dysfunctional eating attitudes. In addition, meals were characterized by negative effects in parents in the clinical group. When compared to the control sample, the feeding interactions between children with FD and their parents were characterized by low dyadic reciprocity, high maternal non-contingency, great interactional conflict and struggles with food. However, no significant correlation emerged either between the severity of malnutrition in infants or the conflict during feeding. CONCLUSION: Our study confirms the relations established in previous research. Finally, future longitudinal studies are needed to further clarify and investigate others factors that may be involved in early feeding disorders.


Asunto(s)
Trastornos de Ingestión y Alimentación en la Niñez/psicología , Padres/psicología , Adulto , Nivel de Alerta , Actitud , Conducta Infantil , Trastornos de la Conducta Infantil/complicaciones , Trastornos de la Conducta Infantil/psicología , Preescolar , Conflicto Psicológico , Ingestión de Alimentos/psicología , Emociones , Femenino , Humanos , Lactante , Masculino , Relaciones Madre-Hijo , Pruebas Neuropsicológicas , Escalas de Valoración Psiquiátrica , Encuestas y Cuestionarios , Temperamento
19.
Int Wound J ; 14(5): 870-873, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28371381

RESUMEN

The effect of nutrition on wound healing is widely recognized, with many studies highlighting the detrimental effect poor nutrition can have on wound healing. In addition, fasting pre-, peri- and postoperatively can contribute to further protein catabolism, leading to morbidity and mortality. By reviewing the current literature, this work evaluates the potential benefits and harms from early feeding (EF) during the early stages postsurgery. Current randomised control trials suggest that the early introduction of nutrients post-surgery may be beneficial for wound healing and recovery from surgery. Additionally, this approach does not seem to impose any increased complications post-operatively. Conversely, although there is ongoing research supporting EF and evidence showing that malnutrition can delay wound healing and recovery, healthcare professionals remain sceptical with a slow uptake in adopting EF protocols.


Asunto(s)
Nutrición Enteral/normas , Complicaciones Posoperatorias/prevención & control , Guías de Práctica Clínica como Asunto , Cicatrización de Heridas/fisiología , Femenino , Humanos , Masculino , Factores de Tiempo
20.
Poult Sci ; 94(9): 2041-8, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26188030

RESUMEN

Early life conditions such as feed and water availability immediately post hatch (PH) and housing conditions may influence immune development and therefore immune reactivity later in life. The current study addressed the consequences of a combination of these 2 early life conditions for immune reactivity, i.e., the specific antibody response towards a non-infectious lung challenge. Broiler chicks received feed and water either immediately p.h. or with a 72 h delay and were either reared in a floor or a cage system. At 4 weeks of age, chicks received either an intra-tracheally administered Escherichia coli lipopolysaccharide (LPS)/Human Serum Albumin (HUSA) challenge or a placebo, and antibody titers were measured up to day 14 after administration of the challenge. Chicks housed on the floor and which had a delayed access to feed p.h. showed the highest antibody titers against HuSA. These chicks also showed the strongest sickness response and poorest performance in response to the challenge, indicating that chicks with delayed access to feed might be more sensitive to an environment with higher antigenic pressure. In conclusion, results from the present study show that early life feeding strategy and housing conditions influence a chick's response to an immune challenge later in life. These 2 early life factors should therefore be taken into account when striving for a balance between disease resistance and performance in poultry.


Asunto(s)
Crianza de Animales Domésticos/métodos , Pollos/fisiología , Privación de Alimentos , Vivienda para Animales , Inmunidad Innata , Animales , Anticuerpos Antibacterianos/sangre , Pollos/inmunología , Dieta/veterinaria , Escherichia coli/fisiología , Métodos de Alimentación , Femenino , Humanos , Lipopolisacáridos/farmacología , Distribución Aleatoria , Albúmina Sérica/farmacología
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