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1.
Proc Natl Acad Sci U S A ; 121(15): e2313903121, 2024 Apr 09.
Artículo en Inglés | MEDLINE | ID: mdl-38557178

RESUMEN

Electromagnetic radiation (EMR) in the environment, particularly in the microwave range, may constitute a public health concern. Exposure to 2.4 GHz EMR modulated by 100 Hz square pulses was recently reported to markedly increase wakefulness in mice. Here, we demonstrate that a similar wakefulness increase can be induced by the modulation frequency of 1,000 Hz, but not 10 Hz. In contrast to the carrier frequency of 2.4 GHz, 935 MHz EMR of the same power density has little impact on wakefulness irrespective of modulation frequency. Notably, the replacement of the 100 Hz square-pulsed modulation by sinusoidal-pulsed modulation of 2.4 GHz EMR still allows a marked increase of wakefulness. In contrast, continuous sinusoidal amplitude modulation of 100 Hz with the same time-averaged power output fails to trigger any detectable change of wakefulness. Therefore, alteration of sleep behavior by EMR depends upon not just carrier frequency but also frequency and mode of the modulation. These results implicate biological sensing mechanisms for specific EMR in animals.


Asunto(s)
Radiación Electromagnética , Vigilia , Ratones , Animales , Campos Electromagnéticos
2.
Environ Health ; 23(1): 82, 2024 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-39390576

RESUMEN

INTRODUCTION: The authors conducted meta-analyses regarding the association between cellular and mobile phone use and brain tumor development by applying various radiofrequency-electromagnetic radiation (RF-EMR) exposure subcategories. With changing patterns of mobile phone use and rapidly developing Wireless Personal Area Network (WPAN) technology (such as Bluetooth), this study will provide insight into the importance of more precise exposure subcategories for RF-EMR. METHODS: The medical librarian searched MEDLINE (PubMed), EMBASE, and the Cochrane Library until 16 December 2020. RESULTS: In these meta-analyses, 19 case-control studies and five cohort studies were included. Ipsilateral users reported a pooled odds ratio (OR) of 1.40 (95% CI 1.21-1.62) compared to non-regular users. Users with years of use over 10 years reported a pooled OR of 1.27 (95% CI 1.08-1.48). When stratified by each type of brain tumor, only meningioma (OR 1.20 (95% CI 1.04-1.39)), glioma (OR 1.45 (95% CI 1.16-1.82)), and malignant brain tumors (OR 1.93 (95% CI 1.55-2.39)) showed an increased OR with statistical significance for ipsilateral users. For users with years of use over 10 years, only glioma (OR 1.32 (95% CI 1.01-1.71)) showed an increased OR with statistical significance. When 11 studies with an OR with cumulative hours of use over 896 h were synthesized, the pooled OR was 1.59 (95% CI 1.25-2.02). When stratified by each type of brain tumor, glioma, meningioma, and acoustic neuroma reported the pooled OR of 1.66 (95% CI 1.13-2.44), 1.29 (95% CI 1.08-1.54), and 1.84 (95% CI 0.78-4.37), respectively. For each individual study that considered cumulative hours of use, the highest OR for glioma, meningioma, and acoustic neuroma was 2.89 (1.41-5.93) (both side use, > 896 h), 2.57 (1.02-6.44) (both side use, > 896 h), and 3.53 (1.59-7.82) (ipsilateral use, > 1640 h), respectively. For five cohort studies, the pooled risk ratios (RRs) for all CNS tumors, glioma, meningioma, and acoustic neuroma, were statistically equivocal, respectively. However, the point estimates for acoustic neuroma showed a rather increased pooled RR for ever-use (1.26) and over 10 years of use (1.61) compared to never-use, respectively. DISCUSSION: In this meta-analysis, as the exposure subcategory used became more concrete, the pooled ORs demonstrated higher values with statistical significance. Although the meta-analysis of cohort studies yielded statistically inconclusive pooled effect estimates, (i) as the number of studies included grows and (ii) as the applied exposure subcategories become more concrete, the pooled RRs could show a different aspect in future research. Additionally, future studies should thoroughly account for changing patterns in mobile phone use and the growing use of earphones or headphones with WPAN technology.


Asunto(s)
Neoplasias Encefálicas , Teléfono Celular , Radiación Electromagnética , Ondas de Radio , Neoplasias Encefálicas/epidemiología , Neoplasias Encefálicas/etiología , Humanos , Ondas de Radio/efectos adversos
3.
Chirality ; 36(5): e23677, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38752253

RESUMEN

Electrons in circular motion emit electromagnetic radiation and lose their energy and angular momentum, both of which are carried away by the radiation field. Electromagnetic radiation from such electrons is not only circularly polarized but also, in general, possessing helical phase structure, the former of which corresponds to spin angular momentum and the latter orbital angular momentum. Based on the classical electrodynamics, we show that the chiral topological property related to the orbital angular momentum arises from deformation of the electromagnetic field due to the relativistic effect.

4.
Proc Natl Acad Sci U S A ; 118(31)2021 08 03.
Artículo en Inglés | MEDLINE | ID: mdl-34330835

RESUMEN

Electromagnetic radiation (EMR) in the environment has increased sharply in recent decades. The effect of environmental EMR on living organisms remains poorly characterized. Here, we report the impact of wireless-range EMR on the sleep architecture of mouse. Prolonged exposure to 2.4-GHz EMR modulated by 100-Hz square pulses at a nonthermal output level results in markedly increased time of wakefulness in mice. These mice display corresponding decreased time of nonrapid eye movement (NREM) and rapid eye movement (REM). In contrast, prolonged exposure to unmodulated 2.4-GHz EMR at the same time-averaged output level has little impact on mouse sleep. These observations identify alteration of sleep architecture in mice as a specific physiological response to prolonged wireless-range EMR exposure.


Asunto(s)
Fenómenos Electromagnéticos , Sueño/efectos de la radiación , Vigilia/efectos de la radiación , Tecnología Inalámbrica , Animales , Ratones
5.
Reprod Health ; 21(1): 12, 2024 Jan 26.
Artículo en Inglés | MEDLINE | ID: mdl-38279180

RESUMEN

BACKGROUND: Endometriosis-related pain encompassing dysmenorrhea, dyspareunia, and chronic pelvic pain, reduces the quality of life in premenopausal women. Although treatment options for endometriosis alleviate this pain, approximately one-third of women still experience pain even after receiving treatment, indicating the need for novel approaches to pain relief in those women. The Angel Touch device (AT-04) is a portable magnetic fields irradiation device that incorporates a combination of mixed alternative magnetic fields at 2 kHz and 83.3 MHz. A phase III trial confirmed the efficacy and safety of AT-02, a prototype of AT-04, for pain relief in patients with fibromyalgia. METHODS: This is a phase III, multicenter, prospective, randomized, sham device-controlled, double-blind, parallel study. The participants will be premenopausal women aged > 18 years who have endometriosis-related pain with at least moderate severity. Considering dropouts, 50 participants have been deemed appropriate. Eligible women will be centrally registered, and the data center will randomly allocate them in a 1:1 ratio to the intervention and control groups. Women in the intervention group will receive electromagnetic wave irradiation generated by AT-04 and those who in the control group will wear a sham device for 16 weeks, and both groups will wear AT-04 for another 4 weeks. The primary outcome measure is the change in the Numeric Rating Scale score at 16 weeks compared with the baseline. Secondary outcome measures are efficacy for pelvic pain including dysmenorrhea and non-menstrual pain, and chronic pelvic pain not related to menstruation, dysmenorrhea, and dyspareunia, and improvement of quality of life during the study period. Safety will be evaluated by device defects and the frequency of adverse events. The study protocol has been approved by the Clinical Study Review Board of Chiba University Hospital, Chiba, Japan, and will be conducted in accordance with the principles of the Declaration of Helsinki and the Japanese Clinical Trials Act and relevant notifications. DISCUSSION: This study aims to develop a novel method of managing endometriosis-related pain. The AT-04 is an ultralow-invasive device that can be used without inhibiting ovulation, suggesting potential benefits to women of reproductive-age. Trial registration number Japan Registry of Clinical Trials (jRCTs032230278).


Endometriosis is a chronic inflammatory disorder that negatively impacts reproductive health via endometriosis-related pain, infertility, and endometriosis-associated ovarian cancer. Although current therapeutic options for endometriosis are effective for the endometriosis-related pain, approximately one-third of women still experience pain even after receiving treatment, indicating the need for novel approaches to pain relief in those women. This is the first randomized controlled trial to investigate the efficacy and safety of a novel portable pain management device, AT-04, that incorporates a combination of mixed alternating magnetic fields, for endometriosis-related pain. This is a multicenter, prospective, sham device-controlled, double-blind, parallel study. Enrolled women will have undergone standard hormonal treatment for endometriosis at baseline, and this allows for assessing whether the device remains effective when used in conjunction with existing treatment methods. The study also will explore the impact of AT-04 on reducing the size of ovarian endometriotic cysts that reflect the activity of endometriosis. The study reflects the strong desire by physicians to liberate women from the unbearable pain associated with endometriosis. The sole efficacy of AT-04 in treating endometriosis-related pain is difficult to evaluate as there is a possibility that menstrual cycles may influence the assessment of pain and quality of life. However, the study findings regarding the effectiveness of AT-04 for the treatment of endometriosis-related pain may benefit women with endometriosis who have pain that is not effectively relieved by other treatments. Consequently, it may contribute to the improvement of reproductive health within society.


Asunto(s)
Dispareunia , Endometriosis , Humanos , Femenino , Endometriosis/terapia , Endometriosis/tratamiento farmacológico , Dismenorrea/terapia , Dismenorrea/complicaciones , Manejo del Dolor , Dispareunia/etiología , Dispareunia/terapia , Calidad de Vida , Estudios Prospectivos , Dolor Pélvico/etiología , Dolor Pélvico/terapia , Resultado del Tratamiento , Ensayos Clínicos Controlados Aleatorios como Asunto , Estudios Multicéntricos como Asunto , Ensayos Clínicos Fase III como Asunto
6.
Parasitol Res ; 123(8): 306, 2024 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-39167261

RESUMEN

The research of the influences of man-made electromagnetic fields on tick physiology has been very sparse and long neglected since the pioneer studies published in 1996 and 2000. Once multiple behavioral tests confirmed an attraction and possible perception of electromagnetic fields in ticks, a new interest in this topic erupted in recent years. In this study, qRT-PCR is utilized to determine the changes in the mRNA transcript levels of neuropeptides SIFamide and myoinhibitory peptide (mip and sifa) and their representative receptors (mip-r1 and sifa-r1) in the synganglia of the tick Ixodes ricinus irradiated by 900 MHz radiofrequency electromagnetic field. It was determined that 40 V/m intensity has a significant suppressory effect on the transcript levels of all genes after at least 60 minutes of constant exposure in both sexes. Commonly occurring intensity of radiation in urban areas (2 V/m) produced an elevation in mRNA levels after various timespans in every gene. A significant decrease of transcript abundances was detected in females after one hour of exposure to 2 V/m. Results of this study widen the knowledge of EMF-induced alterations in the neurophysiology of I. ricinus, the most commonly distributed hard tick in Europe.


Asunto(s)
Ixodes , Animales , Ixodes/genética , Ixodes/efectos de la radiación , Ixodes/fisiología , Femenino , Masculino , Radiación Electromagnética , Neuropéptidos/genética , Neuropéptidos/metabolismo , Campos Electromagnéticos , Regulación de la Expresión Génica/efectos de la radiación , ARN Mensajero/genética , ARN Mensajero/metabolismo , Transcripción Genética/efectos de la radiación
7.
Int J Mol Sci ; 25(14)2024 Jul 18.
Artículo en Inglés | MEDLINE | ID: mdl-39063113

RESUMEN

Exposure to 2.45 GHz electromagnetic radiation (EMR) emitted from commonly used devices has been reported to induce oxidative stress in several experimental models. Our study aims to evaluate the efficacy of sulforaphane, a well-known natural product, in preventing radiation-induced toxic effects caused by a 24 h exposure of SH-SY5Y neuronal-like cells and peripheral blood mononuclear cells (PBMCs) to 2.45 GHz EMR. Cells were exposed to radiation for 24 h in the presence or absence of sulforaphane at different concentrations (5-10-25 µg/mL). Cell viability, mitochondrial activity alterations, the transcription and protein levels of redox markers, and apoptosis-related genes were investigated. Our data showed a reduction in cell viability of both neuronal-like cells and PBMCs caused by EMR exposure and a protective effect of 5 µg/mL sulforaphane. The lowest sulforaphane concentration decreased ROS production and increased the Mitochondrial Transmembrane Potential (Δψm) and the NAD+/NADH ratio, which were altered by radiation exposure. Sulforaphane at higher concentrations displayed harmful effects. The hormetic behavior of sulforaphane was also evident after evaluating the expression of genes coding for Nrf2, SOD2, and changes in apoptosis markers. Our study underlined the vulnerability of neuronal-like cells to mitochondrial dysfunction and oxidative stress and the possibility of mitigating these effects by supplementation with sulforaphane. To our knowledge, there are no previous studies about the effects of SFN on these cells when exposed to 2.45 GHz electromagnetic radiation.


Asunto(s)
Radiación Electromagnética , Isotiocianatos , Leucocitos Mononucleares , Potencial de la Membrana Mitocondrial , Neuronas , Estrés Oxidativo , Sulfóxidos , Isotiocianatos/farmacología , Humanos , Sulfóxidos/farmacología , Leucocitos Mononucleares/efectos de la radiación , Leucocitos Mononucleares/efectos de los fármacos , Leucocitos Mononucleares/metabolismo , Neuronas/efectos de la radiación , Neuronas/efectos de los fármacos , Neuronas/metabolismo , Estrés Oxidativo/efectos de los fármacos , Estrés Oxidativo/efectos de la radiación , Potencial de la Membrana Mitocondrial/efectos de los fármacos , Potencial de la Membrana Mitocondrial/efectos de la radiación , Supervivencia Celular/efectos de los fármacos , Supervivencia Celular/efectos de la radiación , Apoptosis/efectos de los fármacos , Apoptosis/efectos de la radiación , Especies Reactivas de Oxígeno/metabolismo , Factor 2 Relacionado con NF-E2/metabolismo , Factor 2 Relacionado con NF-E2/genética , Mitocondrias/efectos de los fármacos , Mitocondrias/efectos de la radiación , Mitocondrias/metabolismo , Línea Celular Tumoral
8.
Electromagn Biol Med ; : 1-9, 2024 Oct 03.
Artículo en Inglés | MEDLINE | ID: mdl-39361824

RESUMEN

The electromagnetic waves of 2.45 GHz microwave frequency have become abundant in environments worldwide. This study assessed the short-term impact of low-intensity 2.45 GHz exposure on young Arabidopsis thaliana plants. The plants underwent a 48-hour exposure to continuous wave 2.45 GHz microwaves at a power density of 1.0 ± 0.1 W m-2. Experiments were conducted inside anechoic chambers. After the microwave exposure samples were subjected to morphological, genotoxicity, pigmentation, and physiochemical analysis. Microwave exposure elevated the levels of photosynthetic pigments, oxidative stress, guaiacol peroxidase activity, and ascorbic peroxidase activity in plants. Conversely, catalase activity decreased. Photosystem efficiency remained unchanged, while non-photochemical quenching increased. Leaf morphological parameters exhibited no significant alterations during this brief exposure period. Notably, despite shifts in physiological parameters and pigmentations, genomic template stability remained unaffected. The findings suggest that the non-thermal effects of microwave exposure influence the photosystem and plant physiology. Research confirmed the existence of non-thermal effects of microwave exposure; however, these effects are within tolerable limits for Arabidopsis thaliana plants.


Microwaves are a category of radio waves with wavelengths ranging from approximately 30 centimeters to one millimeter. The most utilized microwave frequency these days is 2.45GHz, which is used in everyday devices such as microwaves and WiFi signals. This investigation explored the impact of low-intensity 2.45GHz microwaves on young thale cress (Arabidopsis thaliana) plants for 48hours. In other words, research is comparable to scientific assessing how plants respond to the proximity of a 2G WiFi signal. The exposure resulted in increased pigment production in plants and displayed indications of stress, influencing specific plant activities. However, these alterations did not compromise the stability of the genetic materials of the plants. This suggests that although low-intensity microwaves can affect plant systems, the effects appear to be manageable during brief exposures.

9.
Electromagn Biol Med ; 43(1-2): 19-30, 2024 Apr 02.
Artículo en Inglés | MEDLINE | ID: mdl-38278143

RESUMEN

Electromagnetic radiation (EM) pollution has a certain impact on human life and health, and the reconstruction of the EM space field in this paper is of great practical significance for EM analysis and research. The radial basis function (RBF) sufficiently considers the influence of each sampling point and is more suitable for reconstructing the EM space field than other spatial interpolation methods. Currently, when RBF is used to reconstruct the EM space field, the optimal determination of the basis function and shape parameter (SP) is rarely considered. This ultimately leads to low reconstruction accuracy of the EM space field. Therefore, in this paper, the particle swarm optimization (PSO) is used to calculate the optimal SP of the RBF. On this basis, reliable EM space field reconstruction is performed, which helps people understand the EM distribution characteristics in actual situations from a visual perspective. The EM sampling data of a region on the Yunnan Normal University campus are used as the data source, and the RBF under the optimal parameters is used for EM reconstruction. The accuracy of its interpolation results is evaluated and compared and analyzed with inverse distance weighting (IDW) after distance index optimization. The results show that the RBF under optimal parameters reconstructs the EM space field with high accuracy and good effect, which can truly reflect the actual distribution of EM.


Electromagnetic radiation (EM) pollution has a great impact on the surrounding environment. Therefore, EM space field reconstruction can help us analyze the characteristics of the electromagnetic environment in a visual way. Radial Basis Function (RBF) is a method more suitable for EM space field reconstruction than other methods because it fully considers the influence of each sampling point. However, when currently using RBF to reconstruct the EM space field, few researchers consider how to choose the most appropriate basis function and shape parameter (SP). This results in low reconstruction accuracy. Therefore, this study uses particle swarm optimization (PSO) to find the optimal SP parameters for reliable EM space field reconstruction. The study used the EM sampling data of an area within the campus of Yunnan Normal University as the study material, and a parameter-optimized RBF method was adopted for the reconstruction of the EM space field. The reconstruction results were then evaluated for accuracy and compared and analyzed with the IDW method optimized with a distance index. Research results show that using RBF with optimal parameters to reconstruct the EM space field has high accuracy and can effectively reflect the actual EM distribution, thereby helping people better understand the characteristics of the electromagnetic environment.


Asunto(s)
Radiación Electromagnética
10.
Artículo en Ruso | MEDLINE | ID: mdl-38372736

RESUMEN

OBJECTIVE: To identify features of development of adaptive protective reactions when applying drinking sulfate mineral water (MW) and low-intensity electromagnetic radiation of extremely high frequency (EMR EHF) against the background of a high-calorie diet and after its elimination at an early stage of development of experimental metabolic syndrome. MATERIAL AND METHODS: Experiments were conducted on 40 non-linear male rats with 200-220 g. weight. The model of metabolic syndrome was reproduced for 60 days. All animals were divided into 5 groups: 2 study groups, 2 control groups and 1 intact one. Rats of the 1st study group were given sulfate MW in combination with EMR EHF against the background of a high-calorie diet, controlled by rats receiving only a high-energy diet. Rats of the 2nd study group also received sulfate MW in combination with EMR EHF but when the metabolic syndrome simulation was finished and the high-calorie diet was eliminated, control was done by rats that were given standard food after eliminating the high-energy diet. Liver, testes and blood were objects of the study. Light-optical, morphometric methods of examination and electron microscopy were used. RESULTS AND DISCUSSION: The use of sulfate MW in combination with EMR EHF against the background of the high-calorie diet was the most cause of increased activity of the antioxidant system and the plastic processes were weaker; the activation of natural adaptive reactions was noted after the elimination of the diet that in combination with actions of MW and EMR EHF led to the further intensification of protein synthesis (RNA, DNA, total protein), intensification of cellular and intracellular regeneration processes. The identified adaptive shifts during the action of the studied factors were caused by their antioxidant, membrane stabilizing and detoxifying actions. CONCLUSION: The results of the study can be used to develop the problem of regulating adaptive reactions with the application of therapeutic physical factors and to create new highly effective methods of preventing and treating metabolic syndrome.


Asunto(s)
Agua Potable , Síndrome Metabólico , Masculino , Animales , Ratas , Antioxidantes , Minerales , Radiación Electromagnética , Sulfatos
11.
J Comput Neurosci ; 51(1): 187-200, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36539556

RESUMEN

The interaction between neurons in a neuronal network develops spontaneous electrical activities. But the effects of electromagnetic radiation on these activities have not yet been well explored. In this study, a ring of three coupled 1-dimensional Rulkov neurons and the generated electromagnetic field (EMF) are considered to investigate how the spontaneous activities might change regarding the EMF exposure. By employing the bifurcation analysis and time series, a comprehensive view of neuronal behavioral changes due to electromagnetic inductions is provided. The main findings of this study are as follows: 1) When a neuronal network is showing a spontaneous chaotic firing manner (without any external stimuli), a generated magnetic field inhibits this type of behavior. In fact, EMF completely eliminated the chaotic intrinsic behaviors of the neuronal loop. 2) When the network is exhibiting regular period-3 spiking patterns, the generated magnetic field changes its firing pattern to chaotic spiking, which is similar to epileptic seizures. 3) With weak synaptic connections, electromagnetic radiation inhibits and suppresses neuronal activities. 4) If the external magnetic flux has a high amplitude, it can change the shape of the induction current according to its shape 5) when there are weak synaptic connections in the network, a high-frequency external magnetic flux engenders high-frequency fluctuations in the membrane voltages. On the whole, electromagnetic radiation changes the pattern of the spontaneous activities of neuronal networks in the brain according to synaptic strengths and initial states of the neurons.


Asunto(s)
Modelos Neurológicos , Neuronas , Neuronas/fisiología , Radiación Electromagnética , Campos Electromagnéticos , Electricidad
12.
J Biochem Mol Toxicol ; 37(7): e23351, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36994543

RESUMEN

Electromagnetic radiation (EMR) from wireless devices, particularly mobile phones, is a potentially growing public health concern. In this study, the neuronal effects of EMR on primary cortical neurons (PCNs) from neonatal rat cerebral cortex and the protective role of hispolon (HIS) and its derivatives were investigated as a measure of cranial exposure during mobile phone use. PCNs were isolated and cultured from day-old neonatal rats, then exposed for 2 h to EMR emitted by a mobile phone operating at a frequency of 2100 MHz with 1.6 W/Kg specific absorption rate (SAR) in call-answered mode treated with HIS and its derivatives. The induction of apoptosis through modulation of pro and anti-apoptotic genes via mitochondrial pathway and the protection by the test compounds was assessed. Pyrazole derivatives decreased apoptosis by modulating the levels of pro and anti-apoptotic genes by reducing the levels of reactive oxygen species (ROS) via mitochondrial damage, which was observed in the EMR exposed PCNs. The pyrazole compounds were found to have antioxidative and anti-apoptotic properties. Thus, the neuroprotective mechanisms of the pyrazole derivatives can be investigated further, which may make them appropriate as lead compounds in developing neuroprotective formulations.


Asunto(s)
Teléfono Celular , Estrés Oxidativo , Ratas , Animales , Radiación Electromagnética , Apoptosis/efectos de la radiación , Corteza Cerebral , Neuronas
13.
Environ Res ; 226: 115657, 2023 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-36906274

RESUMEN

INTRODUCTION: The aim of this study is to investigate the relationship between the nationwide cell phone subscription rate and the nationwide incidence of brain tumors in South Korea. The nationwide cell phone subscription rate was used as a proxy for the RF-EMR exposure assessment. METHODS: The data for cell phone subscriptions per 100 persons from 1985 to 2019 were found in the Statistics, International Telecom Union (ITU). The brain tumor incidence data from 1999 to 2018 provided by the South Korea Central Cancer Registry operated by the National Cancer Center were used. RESULTS: In South Korea, the subscription rate increased from 0 per 100 persons in 1991 to 57 per 100 persons in 2000. The subscription rate became 97 per 100 persons in 2009 and 135 per 100 persons in 2019. For the correlation coefficient between cell phone subscription rate before 10 years and ASIR per 100,000, a positive correlation coefficient with a statistical significance was reported in 3 benign brain tumors (International Classification of Diseases, ICD-10 code, D32, D33, and D32.0) and in 3 malignant brain tumors (ICD-10 code, C71.0, C71.1, and C71.2). Positive correlation coefficients with a statistical significance in malignant brain tumors ranged from 0.75 (95% CI 0.46-0.90) for C71.0 to 0.85 (95% CI 0.63-0.93) for C71.1. DISCUSSION: In consideration of the fact that the main route for RF-EMR exposure has been through the frontotemporal side of the brain (the location of both ears), the positive correlation coefficient with a statistical significance in the frontal lobe (C71.1) and temporal lobe (C71.2) can be understood. Statistically insignificant results from recent cohort and large population international studies and contrasting results from many previous case-control studies could indicate a difficulty in identifying a factor as a determinant of a disease in ecological study design.


Asunto(s)
Neoplasias Encefálicas , Teléfono Celular , Humanos , Incidencia , Campos Electromagnéticos , Neoplasias Encefálicas/epidemiología , Neoplasias Encefálicas/etiología , Ondas de Radio/efectos adversos , República de Corea/epidemiología
14.
Ecotoxicol Environ Saf ; 254: 114733, 2023 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-36889209

RESUMEN

The direct biological effects of radiofrequency electromagnetic radiation (RF-EMR) from wireless communication equipment on the testes are still unclear. Our previous study proved that long-term exposure to 2605 MHz RF-EMR gradually damage spermatogenesis and resulted in time-dependent reproductive toxicity by directly disrupting blood-testis barrier circulation. Although short-term exposure did not cause readily observable damage to fertility, whether it caused specific biological effects and how these effects contributed to the time-dependent reproductive toxicity of RF-EMR were currently unknown. Studies on this issue are important for elucidating the time-dependent reproductive toxicity of RF-EMR. The present study established a 2605 MHz RF-EMR (SAR=1.05 W/Kg) scrotal exposure model with rats and extracted primary Sertoli cells for exposure to investigate the direct biological effects of short-term RF-EMR exposure on the testis. The results showed that short-term RF-EMR exposure did not decrease sperm quality and spermatogenesis, but it increased the levels of testicular testosterone (T) and zinc transporter 9 (ZIP9) in Sertoli cells of rats. In vitro, 2605 MHz RF-EMR exposure did not increase the apoptosis rate of Sertoli cells, but it increased the apoptosis rate and MDA of Sertoli cells exposed to H2O2. T reversed these changes and increased ZIP9 level in Sertoli cells, whereas inhibiting ZIP9 expression significantly suppressed these T-mediated protective effects. Moreover, T increased the levels of phosphorylated inositol-requiring enzyme 1 (P-IRE1), phosphorylated protein kinase R (PKR)-like endoplasmic reticulum kinase (P-PERK), phosphorylated eukaryotic initiation factor 2a (P-eIF2a) and phosphorylated activating transcription factor 6 (P-ATF6) in Sertoli cells, and these effects were reversed by ZIP9 inhibition. With prolonged exposure time, testicular ZIP9 was gradually downregulated, and testicular MDA increased. ZIP9 level was negatively correlated with MDA level in the testes of exposed rats. Thus, although short-term exposure to 2605 MHz RF-EMR (SAR=1.05 W/kg) did not significantly disturb spermatogenesis, it suppressed the ability of Sertoli cells to resist external insults, which was rescued by enhancing the ZIP9-centered androgen pathway in the short term. Increasing the unfolded protein response might be an important downstream mechanism involved. These results promote a better understanding of the time-dependent reproductive toxicity of 2605 MHz RF-EMR.


Asunto(s)
Andrógenos , Células de Sertoli , Animales , Masculino , Ratas , Radiación Electromagnética , Peróxido de Hidrógeno , Semen
15.
Sensors (Basel) ; 23(3)2023 Jan 31.
Artículo en Inglés | MEDLINE | ID: mdl-36772589

RESUMEN

We examine the effect of resonant absorption of electromagnetic signals in a silicon semiconductor plasma layer when the dielectric plate is placed behind it both experimentally and numerically. It is shown that such plate acts as a dielectric resonator and can significantly increase the electromagnetic energy absorption in the semiconductor for certain frequencies determined by the dielectric plate parameters. Numerical modelling of the effect is performed under the conditions of conducted experiment. The numerical results are found to be in qualitative agreement with experimental ones. This study confirms the proposed earlier method of increasing the efficiency of bolometric-type detectors of electromagnetic radiation.

16.
Sensors (Basel) ; 23(5)2023 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-36904786

RESUMEN

Since bee traffic is a contributing factor to hive health and electromagnetic radiation has a growing presence in the urban milieu, we investigate ambient electromagnetic radiation as a predictor of bee traffic in the hive's vicinity in an urban environment. To that end, we built two multi-sensor stations and deployed them for four and a half months at a private apiary in Logan, UT, USA. to record ambient weather and electromagnetic radiation. We placed two non-invasive video loggers on two hives at the apiary to extract omnidirectional bee motion counts from videos. The time-aligned datasets were used to evaluate 200 linear and 3,703,200 non-linear (random forest and support vector machine) regressors to predict bee motion counts from time, weather, and electromagnetic radiation. In all regressors, electromagnetic radiation was as good a predictor of traffic as weather. Both weather and electromagnetic radiation were better predictors than time. On the 13,412 time-aligned weather, electromagnetic radiation, and bee traffic records, random forest regressors had higher maximum R2 scores and resulted in more energy efficient parameterized grid searches. Both types of regressors were numerically stable.


Asunto(s)
Conservación de los Recursos Energéticos , Tiempo (Meteorología) , Animales , Abejas , Fenómenos Físicos , Movimiento (Física)
17.
Molecules ; 28(16)2023 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-37630409

RESUMEN

This study focuses on the fabrication of fiber membranes containing different concentrations of AgNO3 via the electrospinning technique. The AgNO3 present in the fibers is subsequently reduced to silver nanoparticles (Ag NPs) through UV irradiation. The resulting nanofiber film is characterized using scanning electron microscopy, X-ray diffraction, and evaluations of its anti-UV and anti-electromagnetic radiation properties. Experimental results demonstrate that increasing the AgNO3 content initially decreases and then increases the fiber diameter and fiber diameter deviation. Under UV light, the nanofibers fuse and bond, leading to an increase in the fiber diameter. AgNO3 is effectively reduced to Ag NPs after UV irradiation for more than 60 min, as confirmed by the characteristic diffraction peaks of Ag NPs in the XRD spectrum of the irradiated AgNO3/PVB fibers. The nanofiber film containing AgNO3 exhibits superior anti-UV performance compared to the film containing AgNO3-derived Ag NPs. The anti-electromagnetic radiation performances of the nanofiber films containing AgNO3 and AgNO3-derived Ag NPs are similar, but the nanofiber film containing AgNO3-derived Ag NPs exhibits higher performance at approximately 2.5 GHZ frequency. Additionally, at an AgNO3 concentration of less than 0.5 wt%, the anti-electromagnetic radiation performance is poor, and the shielding effect of the nanofiber film on medium- and low-frequency electromagnetic waves surpasses that on high-frequency waves. This study provides guidance for the preparation of polyvinyl butyral nanofibers, Ag NPs, and functional materials with anti-ultraviolet and anti-electromagnetic radiation properties.

18.
Exp Appl Acarol ; 91(3): 477-485, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37819593

RESUMEN

Artificial electromagnetic radiation is a new environmental factor that affects animals. Experiments with the effect of radio frequency electromagnetic radiation were focused on both vertebrates and invertebrates. Ticks showed a significant affinity to radiation. Our study is a continuation of this research and its aim was to monitor the effect of radiation on the behavior of four tick species: Ixodes ricinus, Dermacentor reticulatus, Dermacentor marginatus and Haemaphysalis inermis. In total 1,200 ticks, 300 of each species, were tested in modules allowing the choice of an exposed or shielded area. During the test, the ticks were exposed to electro-magnetic radiation of 900 MHz for 24 h. The position of the individuals was recorded and we evaluated the obtained data statistically. We observed a significant preference to the exposed area in both sexes of I. ricinus. Males of D. reticulatus and D. marginatus also showed an affinity to radiation, but not females of both species, nor females and males of H. inermis. The results of the study support the assumption that ticks perceive the electromagnetic field and the observed differences in their response have the potential to help understand the mechanism of perception.


Asunto(s)
Dermacentor , Ixodes , Ixodidae , Humanos , Masculino , Femenino , Animales , Dermacentor/fisiología , Ixodes/fisiología , Ondas de Radio/efectos adversos , Campos Electromagnéticos
19.
Afr J Reprod Health ; 27(5): 95-104, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-37584934

RESUMEN

Extremely low-frequency electromagnetic radiation (ELF-EMF) are generated by electrical devices and power systems (1 to 300 Hz). Although several studies have demonstrated that ELF-EMF may beassociated with an increased risk of adverse pregnancy outcomes, other studies have shown no evidence of associations. This meta-analysis was conducted to assess the effect of extremely low frequency electromagnetic radiation on pregnancy outcomes. The following electronic bibliographic databases were searched to identify relevant studies: PubMed, Web Of Science, Cochrane library, Embase, EBSCO. In addition, the manual retrieval of relevant references was conducted as a supplement. Select all eligible studies published from Database construction library to March 10, 2021. Search type for queue research on influence of electromagnetic field radiation on pregnancy results. Data were screened and extracted independently by two researchers. Review Manager 5.3 software was used for the meta-analysis. There was no significant increase in the risk of miscarriage, stillbirth, birth defects and preterm delivery in the pregnant women who lived near the electromagnetic fields compared with the control group. Conclusions: No correlation has been found between maternal ELF-EMF exposure and miscarriage, stillbirth, neonatal birth defects and preterm delivery, while the effects on small gestational age and low birth weight are still uncertain. Related research with high-quality large samples and different regions are still needed for further verification.


Asunto(s)
Aborto Espontáneo , Nacimiento Prematuro , Recién Nacido , Embarazo , Humanos , Femenino , Mortinato/epidemiología , Resultado del Embarazo/epidemiología , Radiación Electromagnética
20.
Entropy (Basel) ; 25(11)2023 Nov 11.
Artículo en Inglés | MEDLINE | ID: mdl-37998230

RESUMEN

The aim of this study is to explore the insights of the information-theoretic definition of similarity for a multitude of flow systems with wave propagation. This provides dimensionless groups of the form Πinfo=U/c, where U is a characteristic flow velocity and c is a signal velocity or wave celerity, to distinguish different information-theoretic flow regimes. Traditionally, dimensionless groups in science and engineering are defined by geometric similarity, based on ratios of length scales; kinematic similarity, based on ratios of velocities or accelerations; and dynamic similarity, based on ratios of forces. In Part I, an additional category of entropic similarity was proposed based on ratios of (i) entropy production terms; (ii) entropy flow rates or fluxes; or (iii) information flow rates or fluxes. In this Part II, the information-theoretic definition is applied to a number of flow systems with wave phenomena, including acoustic waves, blast waves, pressure waves, surface or internal gravity waves, capillary waves, inertial waves and electromagnetic waves. These are used to define the appropriate Mach, Euler, Froude, Rossby or other dimensionless number(s)-including new groups for internal gravity, inertial and electromagnetic waves-to classify their flow regimes. For flows with wave dispersion, the coexistence of different celerities for individual waves and wave groups-each with a distinct information-theoretic group-is shown to imply the existence of more than two information-theoretic flow regimes, including for some acoustic wave systems (subsonic/mesosonic/supersonic flow) and most systems with gravity, capillary or inertial waves (subcritical/mesocritical/supercritical flow). For electromagnetic wave systems, the additional vacuum celerity implies the existence of four regimes (subluminal/mesoluminal/transluminal/superluminal flow). In addition, entropic analyses are shown to provide a more complete understanding of frictional behavior and sharp transitions in compressible and open channel flows, as well as the transport of entropy by electromagnetic radiation. The analyses significantly extend the applications of entropic similarity for the analysis of flow systems with wave propagation.

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