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1.
Neuropsychol Rehabil ; 33(2): 193-225, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34775908

RESUMEN

Word retraining techniques can improve picture naming of treated items in people with semantic dementia (SD). The utility of this, however, has been questioned given the propensity for under- and overgeneralization errors in naming in SD. Few studies have investigated the occurrence of such errors. This study examined whether, following tailored word retraining: (1) misuse of words increases, (2) the type of naming errors changes, and/or (3) clarity of communication is reduced. Performance on trained and untrained word naming from nine participants with SD who completed a word retraining programme were analysed. Responses from baseline and post-intervention assessments were coded for misuse (i.e., trained word produced for another target item), error type, and communication clarity. All participants showed significant improvement for trained vocabulary. There was no significant increase in misuse of words, with such errors occurring rarely. At a group level, there was an increased tendency toward omission errors for untrained items, and a reduction in semantically related responses. However, this did not impact on clarity scores with no consistent change across participants. In sum, we found no negative impacts following tailored word retraining, providing further evidence of the benefit of these programmes for individuals with SD.


Asunto(s)
Demencia Frontotemporal , Vocabulario , Humanos , Comunicación , Semántica
2.
Neuropsychol Rehabil ; 33(9): 1488-1511, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-35984770

RESUMEN

Word retraining programs have been shown to improve naming ability post-stroke and in progressive aphasias. Here, we investigated benefits for a 22-year-old Danish man (DJ), whose difficulties followed brain damage from heavy alcohol misuse. Using a multiple baseline-across-behaviours design (target behaviour: retrieval of word list items), DJ completed a 4-week "Look, Listen, Repeat" program on a computer. Ninety personally relevant target words were selected to create three matched lists. List 1 was trained for 10 sessions over 2 weeks, followed by 9 sessions for List 2 over 2 weeks, while the third list remained untrained. Naming performance was evaluated at baseline, during the intervention, and at 1 and 4 months post-training. Naming improved following each intervention block (p < .001), with only one data point overlapping between the baseline and treatment phases for trained items. Untrained words remained unchanged (p = 1.00), with 50% of data points non-overlapping across baseline to treatment phases. Performance was maintained over time, and appeared to generalize, with DJ naming more trained objects in their natural setting (85%) than untrained items (64%). While more evidence is needed, brief (20-minute), intensive (5-day/week) word retraining programs may assist word retrieval for people with brain damage associated with alcohol misuse.


Asunto(s)
Alcoholismo , Afasia , Lesiones Encefálicas , Accidente Cerebrovascular , Masculino , Humanos , Adulto Joven , Adulto , Proyectos de Investigación , Alcoholismo/complicaciones , Afasia/complicaciones , Accidente Cerebrovascular/complicaciones , Lesiones Encefálicas/complicaciones , Encéfalo
3.
Audiol Neurootol ; 27(5): 356-367, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35533653

RESUMEN

INTRODUCTION: Several factors are known to influence speech perception in cochlear implant (CI) users. To date, the underlying mechanisms have not yet been fully clarified. Although many CI users achieve a high level of speech perception, a small percentage of patients does not or only slightly benefit from the CI (poor performer, PP). In a previous study, PP showed significantly poorer results on nonauditory-based cognitive and linguistic tests than CI users with a very high level of speech understanding (star performer, SP). We now investigate if PP also differs from the CI user with an average performance (average performer, AP) in cognitive and linguistic performance. METHODS: Seventeen adult postlingually deafened CI users with speech perception scores in quiet of 55 (9.32) % (AP) on the German Freiburg monosyllabic speech test at 65 dB underwent neurocognitive (attention, working memory, short- and long-term memory, verbal fluency, inhibition) and linguistic testing (word retrieval, lexical decision, phonological input lexicon). The results were compared to the performance of 15 PP (speech perception score of 15 [11.80] %) and 19 SP (speech perception score of 80 [4.85] %). For statistical analysis, U-Test and discrimination analysis have been done. RESULTS: Significant differences between PP and AP were observed on linguistic tests, in Rapid Automatized Naming (RAN: p = 0.0026), lexical decision (LexDec: p = 0.026), phonological input lexicon (LEMO: p = 0.0085), and understanding of incomplete words (TRT: p = 0.0024). AP also had significantly better neurocognitive results than PP in the domains of attention (M3: p = 0.009) and working memory (OSPAN: p = 0.041; RST: p = 0.015) but not in delayed recall (delayed recall: p = 0.22), verbal fluency (verbal fluency: p = 0.084), and inhibition (Flanker: p = 0.35). In contrast, no differences were found hereby between AP and SP. Based on the TRT and the RAN, AP and PP could be separated in 100%. DISCUSSION: The results indicate that PP constitute a distinct entity of CI users that differs even in nonauditory abilities from CI users with an average speech perception, especially with regard to rapid word retrieval either due to reduced phonological abilities or limited storage. Further studies should investigate if improved word retrieval by increased phonological and semantic training results in better speech perception in these CI users.


Asunto(s)
Implantación Coclear , Implantes Cocleares , Percepción del Habla , Adulto , Humanos , Lenguaje , Memoria a Corto Plazo , Percepción del Habla/fisiología
4.
Conscious Cogn ; 106: 103433, 2022 11.
Artículo en Inglés | MEDLINE | ID: mdl-36343602

RESUMEN

To clarify the feeling of knowing a name but not being able to recall it, known as having a "tip-of-the-tongue" (TOT) experience, we proposed a TOT model consisting of three stages combining a face recognition model and autonomic sympathetic nerve activity. Since TOT increases with age, we compared two age groups: young (N = 27, M = 20.4 ± 1.5 years) and middle-aged (N = 29, M = 58.5 ± 8.0 years). Experiment 1 showed that successfully naming low-frequency common names increased the skin conductance response (SCR) value, and the time to reach the maximum SCR value was longer. Experiment 2 was a naming task for face photographs. The younger group showed higher SCR values during successfully naming, while the middle-aged group showed similar SCR values for successfully naming and experiencing TOT. Both groups had the longest time to reach maximum SCR in TOT. In this study, physiological arousal of TOT was not affected by aging.


Asunto(s)
Cara , Nombres , Persona de Mediana Edad , Humanos , Adolescente , Adulto Joven , Adulto , Anciano , Recuerdo Mental/fisiología , Envejecimiento/fisiología , Lengua/fisiología
5.
Artículo en Inglés | MEDLINE | ID: mdl-36507588

RESUMEN

BACKGROUND: Word retrieval skills change across the lifespan. Permanent alterations in the form of decreased accuracy or increased response time can be a consequence of both normal ageing processes or the presence of acquired and neurodegenerative disorders (e.g., aphasia and dementia). Despite the extensive literature exploring the neuroanatomical underpinnings of word retrieval, psycholinguistic, biolinguistic and theoretical explanations, and the vast amount of evidence from primary and secondary language disorders, the best approach to consistently capture these changes is yet to be discovered. AIMS: The goal of this paper is to determine which method(s) stand(s) as the most suitable candidate(s) to provide an accurate picture of word retrieval in the oral production of different groups of adult speakers, including cases of healthy ageing, preclinical Alzheimer's disease (AD), mild cognitive impairment (MCI), aphasia and dementia. METHODS & PROCEDURES: Using an integrative review of recent peer-reviewed journal articles, we provide an overview of the different behavioural methods traditionally used to measure oral naming skills in research-oriented and clinical protocols and discuss their main advantages and limitations. MAIN CONTRIBUTION: Most existing studies are based on the results of people with diagnosed language disorders. Despite the growing interest, the reliability of the majority of the tasks to detect subtle changes associated with healthy ageing, MCI and preclinical AD are yet to be demonstrated, and the delicate balance between informativeness and efficiency (especially in terms of administration time and variable control) in experimental protocols is yet to be achieved. In this article we propose the pursuit of an integrative overarching methodology to characterize all naming deficits (from anecdotal to permanent) and all adult populations (from healthy to pathological ageing). CONCLUSIONS & IMPLICATIONS: A combination of spontaneous speech data and results from structured tasks stands as the best approach to capture changes in word retrieval skills of adult speakers with and without observable deficits. This review can guide future reflections on the necessary prerequisites of purpose-oriented, sensitive and reliable protocols for the detection of incipient word retrieval problems, thus contributing to the early diagnosis and the design of personalized multicomponent treatments. WHAT THIS PAPER ADDS: What is already known on this subject Word retrieval skills change during adulthood as a consequence of the neurological degradation associated with ageing. These changes are more dramatic in the event of acquired and neurodegenerative disorders. Numerous studies based on people with observable language disorders have addressed the multiplicity of factors involved in word retrieval and provided evidence of potential loci of impairment from a neuroanatomical, cognitive and/or (psycho-)linguistic perspective. What this paper adds to existing knowledge This study focuses on methodological strategies to assess naming skills and provides a reflection on generally accepted good practices and unresolved challenges to inform task selection, emphasizing the necessity for a combination of methods to best capture the actual problems and needs of people confronting word retrieval difficulties in their daily lives. Task selection, variable control and administration time stand as key concepts to adjust to the requirements of research and clinical contexts. What are the potential or actual clinical implications of this work? The results of this review can orient future research towards the creation of sensitive, reliable and (ecologically) valid materials for the (early) detection of word retrieval deficits and for the customization of treatment protocols to alleviate or palliate their effects.

6.
Brain Cogn ; 148: 105694, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-33503544

RESUMEN

Individuals with a premutation of the fragile X mental retardation (FMR1) gene are at risk for a variety of psychological, physical, and cognitive issues, including difficulty with word retrieval. The present study examined three indicators of word retrieval difficulty; reduced productivity, reduced lexical diversity, and increased errors in word retrieval in a group of 38 female premutation carriers during standard-length speech samples collected over a period of eight years. Our results revealed that as women aged, they produced fewer words, produced fewer different words, and had greater word retrieval errors. In addition, the rate of word retrieval errors was highly correlated between two speaking contexts, indicating that this difficulty was pervasive and not solely the result of speaking in monologue. Our results suggest that subtle areas of cognitive decline emerge at a much earlier age among female premutation carriers than would be expected during healthy aging.


Asunto(s)
Síndrome del Cromosoma X Frágil , Discapacidad Intelectual , Adulto , Femenino , Proteína de la Discapacidad Intelectual del Síndrome del Cromosoma X Frágil/genética , Heterocigoto , Humanos , Mutación
7.
Hum Brain Mapp ; 41(1): 80-94, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31515906

RESUMEN

This functional magnetic resonance imaging study established that different portions of the ventrolateral prefrontal cortex (vlPFC) support reactive and proactive language control processes during multilingual word retrieval. The study also examined whether proactive language control consists in the suppression of the nontarget lexicon. Healthy multilingual volunteers participated in a task that required them to name pictures alternately in their dominant and less-dominant languages. Two crucial variables were manipulated: the cue-target interval (CTI) to either engage (long CTI) or prevent (short CTI) proactive control processes, and the cognate status of the to-be-named pictures (noncognates vs. cognates) to capture selective pre-activation of the target language. The results of the functional connectivity analysis showed a clear segregation between functional networks related to mid-vlPFC and anterior vlPFC during multilingual language production. Furthermore, the results revealed that multilinguals engage in proactive control to prepare the target language. This proactive modulation, enacted by anterior vlPFC, is achieved by boosting the activation of lexical representations in the target language. Finally, control processes supported by both mid-vlPFC and the left inferior parietal lobe, were similarly engaged by reactive and proactive control, possibly exerted on phonological representations to reduce cross-language interference.


Asunto(s)
Conectoma , Función Ejecutiva/fisiología , Recuerdo Mental/fisiología , Corteza Prefrontal/fisiología , Psicolingüística , Adulto , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Multilingüismo , Corteza Prefrontal/diagnóstico por imagen , Adulto Joven
8.
Proc Natl Acad Sci U S A ; 114(23): E4530-E4538, 2017 06 06.
Artículo en Inglés | MEDLINE | ID: mdl-28533406

RESUMEN

Word retrieval is core to language production and relies on complementary processes: the rapid activation of lexical and conceptual representations and word selection, which chooses the correct word among semantically related competitors. Lexical and conceptual activation is measured by semantic priming. In contrast, word selection is indexed by semantic interference and is hampered in semantically homogeneous (HOM) contexts. We examined the spatiotemporal dynamics of these complementary processes in a picture naming task with blocks of semantically heterogeneous (HET) or HOM stimuli. We used electrocorticography data obtained from frontal and temporal cortices, permitting detailed spatiotemporal analysis of word retrieval processes. A semantic interference effect was observed with naming latencies longer in HOM versus HET blocks. Cortical response strength as indexed by high-frequency band (HFB) activity (70-150 Hz) amplitude revealed effects linked to lexical-semantic activation and word selection observed in widespread regions of the cortical mantle. Depending on the subsecond timing and cortical region, HFB indexed semantic interference (i.e., more activity in HOM than HET blocks) or semantic priming effects (i.e., more activity in HET than HOM blocks). These effects overlapped in time and space in the left posterior inferior temporal gyrus and the left prefrontal cortex. The data do not support a modular view of word retrieval in speech production but rather support substantial overlap of lexical-semantic activation and word selection mechanisms in the brain.


Asunto(s)
Lóbulo Frontal/fisiología , Habla/fisiología , Adulto , Electrocorticografía , Fenómenos Electrofisiológicos , Femenino , Humanos , Lenguaje , Masculino , Estimulación Luminosa , Semántica , Medición de la Producción del Habla , Lóbulo Temporal/fisiología , Adulto Joven
9.
Int J Geriatr Psychiatry ; 34(4): 548-554, 2019 04.
Artículo en Inglés | MEDLINE | ID: mdl-30548691

RESUMEN

OBJECTIVES: The aim of this study was to examine awareness of decline in memory and in language in individuals with Alzheimer's disease (AD), by comparing participant and informant ratings, as well as these ratings and actual test performance. METHODS: We analyzed data from 149 individuals with AD enrolled in the Alzheimer's Disease Neuroimaging Initiative (ADNI) who filled the Everyday Cognition questionnaire and performed memory and language tasks. RESULTS: Participants provided significantly lower assessments of decline than did informants for both memory and language. There was a negative association between informant ratings and memory test scores but no association between participant ratings and memory test scores. Both participant and informant ratings correlated negatively with performance on the language tests. Informant, but not participant, ratings contributed to the prediction of one memory variable beyond demographic factors. Participant ratings contributed to the prediction of language scores beyond demographic factors more than did informant ratings. CONCLUSIONS: The findings reflect better awareness of decline in language than of decline in memory in individuals with AD.


Asunto(s)
Enfermedad de Alzheimer , Concienciación , Trastornos del Lenguaje , Lenguaje , Trastornos de la Memoria , Memoria , Anciano , Enfermedad de Alzheimer/complicaciones , Enfermedad de Alzheimer/diagnóstico por imagen , Femenino , Humanos , Trastornos del Lenguaje/etiología , Masculino , Trastornos de la Memoria/etiología , Neuroimagen , Pruebas Neuropsicológicas
10.
Conscious Cogn ; 71: 18-29, 2019 05.
Artículo en Inglés | MEDLINE | ID: mdl-30921682

RESUMEN

Many individuals with aphasia report the ability to say words in their heads despite spoken naming difficulty. Here, we examined individual differences in the experience of inner speech (IS) in participants with aphasia to test the hypotheses that self-reported IS reflects intact phonological retrieval and that articulatory output processing is not essential to IS. Participants (N = 53) reported their ability to name items correctly internally during a silent picture-naming task. We compared this measure of self-reported IS to spoken picture naming and a battery of tasks measuring the underlying processes required for naming (i.e., phonological retrieval and output processing). Results from three separate analyses of these measures indicate that self-reported IS relates to phonological retrieval and that speech output processes are not a necessary component of IS. We suggest that self-reported IS may be a clinically valuable measure that could assist in clinical decision-making regarding anomia diagnosis and treatment.


Asunto(s)
Anomia/fisiopatología , Afasia/fisiopatología , Lenguaje , Reconocimiento Visual de Modelos/fisiología , Habla/fisiología , Adulto , Anciano , Anciano de 80 o más Años , Aptitud/fisiología , Femenino , Humanos , Masculino , Recuerdo Mental/fisiología , Persona de Mediana Edad , Autoinforme
11.
Brain ; 140(11): 3039-3054, 2017 11 01.
Artículo en Inglés | MEDLINE | ID: mdl-29053773

RESUMEN

See Thompson and Woollams (doi:10.1093/brain/awx264) for a scientific commentary on this article. Previous research with aphasic patients has shown that picture naming can be facilitated by concurrent phonemic cueing [e.g. initial phoneme(s) of the word that the patient is trying to retrieve], both as an immediate word retrieval technique, and when practiced repeatedly over time as a long-term anomia treatment. Here, to investigate the neural mechanisms supporting word retrieval, we adopted­for the first time­a functional magnetic resonance imaging task using the same naming procedure as it occurs during the anomia treatment process. Before and directly after a 6-week anomia treatment programme, 18 chronic aphasic stroke patients completed our functional magnetic resonance imaging protocol­a picture naming task aided by three different types of phonemic cues (whole words, initial phonemes, final phonemes) and a noise-control condition. Patients completed a naming task based on the training materials, and a more general comprehensive battery of language tests both before and after the anomia treatment, to determine the effectiveness and specificity of the therapy. Our results demonstrate that the anomia treatment was effective and specific to speech production, significantly improving both patients' naming accuracy and reaction time immediately post-treatment (unstandardized effect size: 29% and 17%, respectively; Cohen's d: 3.45 and 1.83). Longer term gains in naming were maintained 3 months later. Functional imaging results showed that both immediate and long-term facilitation of naming involved a largely overlapping bilateral frontal network including the right anterior insula, inferior frontal and dorsal anterior cingulate cortices, and the left premotor cortex. These areas were associated with a neural priming effect (i.e. reduced blood oxygen level-dependent signal) during both immediate (phonemically-cued versus control-cue conditions), and long-term facilitation of naming (i.e. treated versus untreated items). Of note is that different brain regions were sensitive to different phonemic cue types. Processing of whole word cues was associated with increased activity in the right angular gyrus; whereas partial word cues (initial and final phonemes) recruited the left supplementary motor area, and right anterior insula, inferior frontal cortex, and basal ganglia. The recruitment of multiple and bilateral areas may help explain why phonemic cueing is such a successful behavioural facilitation tool for anomia treatment. Our results have important implications for optimizing current anomia treatment approaches, developing new treatments, and improving speech outcome for aphasic patients.


Asunto(s)
Anomia/diagnóstico por imagen , Anomia/terapia , Afasia/diagnóstico por imagen , Afasia/terapia , Señales (Psicología) , Imagen por Resonancia Magnética/métodos , Adulto , Anciano , Anomia/etiología , Afasia/etiología , Enfermedad Crónica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estimulación Luminosa/métodos , Tiempo de Reacción/fisiología , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/diagnóstico por imagen , Accidente Cerebrovascular/terapia , Resultado del Tratamiento , Adulto Joven
12.
J Psycholinguist Res ; 47(1): 169-178, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29019103

RESUMEN

We tested the frequent assumption that the difficulty of word retrieval increases when a speaker is being observed and evaluated. We modified the Trier Social Stress Test (TSST) so that participants believed that its evaluative observation components continued throughout the duration of a subsequent word retrieval task, and measured participants' reported tip of the tongue (TOT) states. Participants in this TSST condition experienced more TOTs than participants in a comparable, placebo TSST condition in which there was no suggestion of evaluative observation. This experiment provides initial evidence confirming the assumption that evaluative observation by a third party can be disruptive to word retrieval. We interpret our findings by proposing an extension to a well-supported theoretical model of TOTs.


Asunto(s)
Afecto , Cognición , Recuerdo Mental , Estrés Psicológico/psicología , Femenino , Humanos , Masculino , Modelos Psicológicos , Adulto Joven
13.
J Int Neuropsychol Soc ; 23(1): 44-55, 2017 01.
Artículo en Inglés | MEDLINE | ID: mdl-27748216

RESUMEN

OBJECTIVES: Mild cognitive impairments (MCI) is a transitional state in aging associated with increased risk of incident dementia. The current study investigated whether MCI status moderated the effect of time on word generation during verbal fluency tasks. Specifically, the objective was to determine whether MCI status had differential effects on initial automatic or latter more effortful retrieval processes of fluency tasks. METHODS: Participants were community residing older adults enrolled in a longitudinal cohort study. Of the 408 participants, 353 were normal (age=76.06±6.61; %female=57.8) and 55 were diagnosed with MCI (age=78.62±7.00; %female=52.7). Phonemic and category fluency were each administered for 60 s, but performance was recorded at three consecutive 20-s intervals (0-20 s [T1], 21-40 s [T2], 41-60 s [T3]. Separate linear mixed effects models for each fluency task were used to determine the effects of group, time, and their interaction on word generation. RESULTS: In both fluency tasks, word generation declined as a function of time. Individuals with MCI generated fewer words compared to controls during the first 20 s of phonemic (beta=-1.56; p<.001; d=0.28) and category fluency (beta=-1.85; p<.001; d=0.37). Group by time interactions revealed that individuals with MCI demonstrated attenuated declines in word generation from the first to the second and third time intervals of both phonemic ([T1 vs. T2] beta=2.17, p=.001; d=0.41; [T1 vs. T3]beta=2.28, p=.001; d=0.45) and category ([T1 vs. T2] beta= 2.22, p=.002; d=0.50; [T1 vs. T3]beta=3.16, p<.001; d=0.71) fluency. CONCLUSIONS: Early automatic retrieval processes in verbal fluency tasks are compromised in MCI. (JINS, 2017, 23, 44-55).


Asunto(s)
Disfunción Cognitiva/complicaciones , Disfunción Cognitiva/psicología , Trastornos del Lenguaje/etiología , Conducta Verbal/fisiología , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Vida Independiente , Trastornos del Lenguaje/diagnóstico , Modelos Lineales , Masculino , Pruebas Neuropsicológicas , Factores de Tiempo
14.
Cogn Psychol ; 79: 68-101, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25917550

RESUMEN

Comprehenders predict upcoming speech and text on the basis of linguistic input. How many predictions do comprehenders make for an upcoming word? If a listener strongly expects to hear the word "sock", is the word "shirt" partially expected as well, is it actively inhibited, or is it ignored? The present research addressed these questions by measuring the "downstream" effects of prediction on the processing of subsequently presented stimuli using the cumulative semantic interference paradigm. In three experiments, subjects named pictures (sock) that were presented either in isolation or after strongly constraining sentence frames ("After doing his laundry, Mark always seemed to be missing one…"). Naming sock slowed the subsequent naming of the picture shirt - the standard cumulative semantic interference effect. However, although picture naming was much faster after sentence frames, the interference effect was not modulated by the context (bare vs. sentence) in which either picture was presented. According to the only model of cumulative semantic interference that can account for such a pattern of data, this indicates that comprehenders pre-activated and maintained the pre-activation of best sentence completions (sock) but did not maintain the pre-activation of less likely completions (shirt). Thus, comprehenders predicted only the most probable completion for each sentence.


Asunto(s)
Comprensión , Lenguaje , Semántica , Señales (Psicología) , Humanos , Modelos Psicológicos , Reconocimiento Visual de Modelos , Tiempo de Reacción , Análisis y Desempeño de Tareas
16.
Neuropsychologia ; 192: 108734, 2024 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-37952713

RESUMEN

PURPOSE: Prior studies have shown that people with aphasia (PWA) have demonstrated superior language performance for emotional compared to nonemotional stimuli on a range of tasks, including auditory comprehension, verbal pragmatics, repetition, reading, and writing. However, studies on word retrieval, specifically, have suggested a possible interference effect of emotion on naming. The purpose of this study was to examine the effect of the emotional valence of stimuli on word retrieval in a series of naming tasks in PWA. METHOD: Thirteen PWA and 13 neurotypical controls participated in four single-word naming tasks, including 1) object picture naming, 2) action picture naming, 3) category-member generation, and 4) verb generation. Each task included three valence sets of positively-, negatively-, and neutrally-rated pictures or words, which were obtained from the standardized International Affective Picture System (Lang et al., 2008) and the Affective Norms for Emotional Words (Bradley and Lang, 1999) databases. Accuracy and reaction time (RT) were measured and compared across groups, tasks, and valence sets. RESULTS: Emotional stimuli, especially negative stimuli, resulted in worse naming performance, as measured by accuracy and RT, compared to nonemotional stimuli in PWA and neurotypical controls. This effect was relatively robust across the four naming tasks. In most cases, negative stimuli resulted in lower accuracy and slower RT than positive stimuli. CONCLUSIONS: These findings suggest that stimulus valence may interfere with word retrieval for PWA and neurotypical adults and that this effect is robust across different types of naming tasks that vary by word class (nouns versus verbs) and stimulus type (pictures versus words). Negative stimuli resulted in worse naming performance than positive stimuli. These results suggest that emotionality of stimuli is an important variable to consider in word retrieval research.


Asunto(s)
Afasia , Adulto , Humanos , Lenguaje , Comprensión , Tiempo de Reacción , Emociones
17.
Clin Neuropsychol ; 38(1): 164-181, 2024 01.
Artículo en Inglés | MEDLINE | ID: mdl-37035940

RESUMEN

Objective: Historically, naming has been assessed with visual object naming; however, we have found that auditory description naming significantly enhances lateralization and localization of dysfunction. We previously published auditory naming (ANT) and complementary Visual Naming Tests (VNT) for young adults, and recently developed these measures for children (ages 6-15 years) and older adults (ages 56-100 years). Here, we update the original stimuli and more rigorously norm the tests for ages 16-55, addressing prior limitations. Methods: Test stimuli were selected based on item characteristics and preliminary screening, eliminating those with less than 90% name agreement. A sample of 178 healthy individuals ages 16-55 years were administered the updated ANT and VNT, and other standardized measures, either in person (n = 114) or via telehealth (n = 64). Results: With no effect of age, yet a significant influence of education, education-based normative data are provided for accuracy, tips-of-the-tongue (i.e. delayed, accurate responses plus correct responses following phonemic cueing), and an aggregate Summary Score. Internal and test-retest reliability coefficients were reasonable (.67-.90). Conclusions: These measures provide updated and improved naming assessment for ages 16-55 years, contributing to a contiguous set of naming tests for school-aged children through elderly adults. Compared to the original ANT and VNT, these measures were designed to have stimuli longevity, and offer reduced item burden and evidence-based recommendations for performance measures with the greatest clinical sensitivity. The addition of these measures enables continuity in assessment across the age span, facilitating longitudinal assessment related to disease progression or therapeutic intervention.


Asunto(s)
Señales (Psicología) , Anciano , Niño , Adulto Joven , Humanos , Reproducibilidad de los Resultados , Pruebas Neuropsicológicas
18.
Front Psychol ; 15: 1372912, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38529093

RESUMEN

Pupil dilation has been associated with the effort required to perform various cognitive tasks. At the lexical level, some studies suggest that this neurophysiological measure would provide objective, real-time information during word processing and lexical access. However, due to the scarcity and incipient advancement of this line of research, its applicability, use, and sensitivity are not entirely clear. This scoping review aims to determine the applicability and usefulness of pupillometry in the study of lexical access by providing an up-to-date overview of research in this area. Following the PRISMA protocol, 16 articles were included in this review. The results show that pupillometry is a highly applicable, useful, and sensitive method for assessing lexical skills of word recognition, word retrieval, and semantic activation. Moreover, it easily fits into traditional research paradigms and methods in the field. Because it is a non-invasive, objective, and automated procedure, it can be applied to any population or age group. However, the emerging development of this specific area of research and the methodological diversity observed in the included studies do not yet allow for definitive conclusions in this area, which in turn does not allow for meta-analyses or fully conclusive statements about what the pupil response actually reflects when processing words. Standardized pupillary recording and analysis methods need to be defined to generate more accurate, replicable research designs with more reliable results to strengthen this line of research.

19.
J Res Med Sci ; 18(4): 274-6, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24124422

RESUMEN

BACKGROUND: Multiple sclerosis (MS) is a common inflammatory - degenerative disease of myelin sheet of central nervous system that affects more young people. These patients show some degrees of cognition problems such as memory and processing disorders. The aim of this study was to evaluate the speed processing ability by word finding assessment in three categories include fruits, animals and objects in MS patients. MATERIALS AND METHODS: This study carried out as case-control and descriptive-analytic on 47 MS patients and 29 healthy controls. We measured the reaction time (RT) in three stages. Each stage includes 25 words (animals, fruits and objects words with high familiarity) that were presented randomly. In each stage, the subject should press a key when recognized the target category. Collected data analyzed with repeated measure ANOVA, two-way ANOVA test, and independent-samples t-test. RESULTS: MS patients in comparison to normal healthy subjects show delay in speed of processing in which there was significant difference between MS patients and control subjects in mean reaction time in all three categories (P < 0.001). CONCLUSION: The speed of processing is impaired in MS patients. Consequently, more evaluation and planning treatment programs based of speed processing for memory in these patients are necessary for them because of the role of memory in daily activities of life.

20.
Int J Speech Lang Pathol ; 25(5): 768-786, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-36017636

RESUMEN

Purpose: There is a growing body of evidence showing the benefit of Semantic Feature Analysis in the treatment of word finding abilities in people with aphasia. The original technique was grounded in the hypothesis that the activation of semantic features spreads to the target and thereby facilitates its subsequent retrieval. However, it remains unclear the extent to which the focus on semantic features influences the treatment effects. The aim of this study was therefore to shed light on this issue by examining the effect of priming with semantic features (parts and functions) on target retrieval across a case series of people with aphasia.Method: 10 people with aphasia and word retrieval impairments were primed with spoken forms of words that were either the target name (identity condition, e.g. car), parts of the target (e.g. wheel) or functions of the target (e.g. drive) before later being asked to name a picture of that target. An unrelated prime condition (e.g. employ) was used as a control for test-retest effects.Result: At a group level, there was speeding of reaction times in picture naming in the identity condition relative to the unrelated condition; however, no effect of priming was found for either parts or functions. There was significantly better response accuracy in post-priming naming, but this effect did not reach significance for any individual experimental condition (identity, parts, functions) as compared to the unrelated condition, although the identity condition showed numerical improvement while the other two conditions showed decline.Conclusion: Given the lack of evidence for facilitatory effects from parts and functions of a target in a priming task, this research suggests that further research is warranted on the extent to which the improvement in word retrieval subsequent to Semantic Feature Analysis is caused by the emphasis on production of semantic features rather than from the repetition of the target name.


Asunto(s)
Afasia , Semántica , Humanos , Afasia/etiología , Cognición , Tiempo de Reacción/fisiología
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