RESUMEN
Although acute retinal necrosis (ARN) and optic neuritis following herpes encephalitis are known causes of acute visual impairment associated with herpes simplex virus (HSV) infection, there have been no reports of parainfectious optic neuritis associated with genital HSV type 2 (HSV-2) infection. A young Japanese woman developed unilateral optic neuritis 7 days after the onset of genital HSV-2 infection. Ophthalmologic examination revealed no findings suggestive of ARN and both multiple sclerosis and neuromyelitis optica were ruled out by the brain images and serum antibody testing. An oral steroid therapy improved her symptoms. Here, we describe the first case of parainfectious optic neuritis associated with genital HSV-2 infection.
Asunto(s)
Herpes Genital/complicaciones , Herpes Genital/diagnóstico por imagen , Herpesvirus Humano 2/aislamiento & purificación , Neuritis Óptica/diagnóstico por imagen , Neuritis Óptica/etiología , Adulto , Antiinflamatorios/administración & dosificación , Femenino , Herpes Genital/tratamiento farmacológico , Humanos , Neuritis Óptica/tratamiento farmacológico , Prednisolona/administración & dosificaciónRESUMEN
We present the PET/CT findings of extensive disseminated genital herpes simplex virus infection in a 29-year-old woman known with disseminated anaplastic lymphoma kinase-mutated nonsmall lung cancer. PET/CT revealed extensive involvement of the outer and inner genitalia, multiple lymph nodes extending from the porta hepatis to the groins, and involvement of the liver. Disseminated herpes simplex virus infection is well described in neonates and immunocompromised individuals but very rare in immunocompetent adults as was the case with this patient.