Detalhe da pesquisa
1.
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Blood
; 138(9): 790-805, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34473231
2.
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.
Blood
; 131(24): 2682-2697, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29592892
3.
The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Nucleic Acids Res
; 45(11): 6350-6361, 2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28369554
4.
Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.
Blood
; 124(12): 1915-25, 2014 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122609
5.
Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.
Stem Cells
; 31(6): 1202-12, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23495171
6.
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells.
Oncogene
; 42(12): 881-893, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36725889
7.
Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.
J Biol Chem
; 285(44): 33949-58, 2010 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20716524
8.
Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset.
Oncotarget
; 8(18): 30199-30216, 2017 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28415816
9.
Pim1 kinase regulates c-Kit gene translation.
Exp Hematol Oncol
; 5: 31, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28042518
10.
Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
Cancer Res
; 75(24): 5318-28, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26670562
11.
Thioredoxin and hematologic malignancies.
Adv Cancer Res
; 122: 245-79, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24974184
12.
Using quantitative real-time PCR to determine donor cell engraftment in a competitive murine bone marrow transplantation model.
J Vis Exp
; (73): e50193, 2013 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525072
13.
Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.
J Hematol Oncol
; 6: 12, 2013 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23360755
14.
Proteomic analysis of murine bone marrow niche microenvironment identifies thioredoxin as a novel agent for radioprotection and for enhancing donor cell reconstitution.
Exp Hematol
; 41(11): 944-56, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994289
15.
IKKß regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells.
PLoS One
; 6(4): e18447, 2011 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21490922
16.
Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable.
Mol Cell Biol
; 30(6): 1528-40, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20065032
17.
The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.
J Biol Chem
; 283(36): 24718-28, 2008 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18566450