Detalhe da pesquisa
1.
Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy.
Brain
; 144(10): 3226-3238, 2021 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964142
2.
The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines.
Proc Natl Acad Sci U S A
; 109(2): 582-7, 2012 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22184247
3.
Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.
BMC Genomics
; 15: 1144, 2014 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25527049
4.
Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain.
Bioorg Med Chem Lett
; 22(8): 2932-7, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421020
5.
Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers.
Sci Rep
; 11(1): 19877, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34615939
6.
Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.
Bioorg Med Chem Lett
; 20(15): 4359-63, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615696
7.
Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK1 receptor.
Bioorg Med Chem Lett
; 20(19): 5925-32, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20729082
8.
Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK1 antagonists.
Bioorg Med Chem Lett
; 20(6): 2007-12, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20153964
9.
Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists.
Bioorg Med Chem
; 16(5): 2156-70, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18248994
10.
Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist.
Eur J Pharmacol
; 527(1-3): 44-51, 2005 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16310181
11.
Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils.
Pain
; 67(1): 189-195, 1996 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-8895247
12.
2,3-diaminopyridine bradykinin B1 receptor antagonists.
J Med Chem
; 47(26): 6439-42, 2004 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15588075
13.
Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists.
J Med Chem
; 54(20): 7350-62, 2011 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21923175
14.
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
J Med Chem
; 53(8): 3330-48, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20307063
15.
The search for novel TRPV1-antagonists: from carboxamides to benzimidazoles and indazolones.
Bioorg Med Chem Lett
; 16(11): 2872-6, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16563760
16.
Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin.
J Pharmacol Exp Ther
; 303(3): 1052-60, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12438527
17.
Discovery of a potent, non-peptide bradykinin B1 receptor antagonist.
J Am Chem Soc
; 125(25): 7516-7, 2003 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12812482