Detalhe da pesquisa
1.
Cryo-EM structure of the human cardiac myosin filament.
Nature
; 623(7988): 853-862, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914935
2.
Integrated multi-omic characterization of congenital heart disease.
Nature
; 608(7921): 181-191, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732239
3.
Cardiac length-dependent activation driven by force-dependent thick-filament dynamics.
Biophys J
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38807364
4.
Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure With Pulmonary Hypertension.
Circulation
; 147(25): 1919-1932, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37194598
5.
Hypertrophic cardiomyopathy ß-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state.
Proc Natl Acad Sci U S A
; 118(24)2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117120
6.
Predominant myosin superrelaxed state in canine myocardium with naturally occurring dilated cardiomyopathy.
Am J Physiol Heart Circ Physiol
; 325(3): H585-H591, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37505469
7.
History-dependent muscle resistance to stretch remains high after small, posturally relevant pre-movements.
J Exp Biol
; 226(18)2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37661732
8.
An in silico study of the effects of left ventricular assist device on right ventricular function and inter-ventricular interaction.
Artif Organs
; 47(12): 1831-1847, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37746896
9.
FiberSim: A flexible open-source model of myofilament-level contraction.
Biophys J
; 121(2): 175-182, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34932957
10.
Reduced cardiac muscle power with low ATP simulating heart failure.
Biophys J
; 121(17): 3213-3223, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35918899
11.
Chaperone-mediated autophagy protects cardiomyocytes against hypoxic-cell death.
Am J Physiol Cell Physiol
; 323(5): C1555-C1575, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584327
12.
Renal Angiotensinogen Is Predominantly Liver Derived in Nonhuman Primates.
Arterioscler Thromb Vasc Biol
; 41(11): 2851-2853, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496634
13.
MgADP Promotes Myosin Head Movement toward Actin at Low [Ca2+] to Increase Force Production and Ca2+-Sensitivity of Contraction in Permeabilized Porcine Myocardial Strips.
Int J Mol Sci
; 23(23)2022 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499408
14.
Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I.
J Biol Chem
; 295(14): 4398-4410, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086378
15.
Fast-relaxing cardiomyocytes exert a dominant role in the relaxation behavior of heterogeneous myocardium.
Arch Biochem Biophys
; 697: 108711, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271148
16.
Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries.
Kidney Int
; 97(1): 143-155, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31739987
17.
Myosins may know when to hold and when to fold.
Biophys J
; 123(5): 525-526, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297835
18.
A short history of the development of mathematical models of cardiac mechanics.
J Mol Cell Cardiol
; 127: 11-19, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503754
19.
Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance.
J Biomech Eng
; 141(6)2019 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30098173
20.
Force-Dependent Recruitment from the Myosin Off State Contributes to Length-Dependent Activation.
Biophys J
; 115(3): 543-553, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054031