Detalhe da pesquisa
1.
Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.
Drug Metab Dispos
; 52(5): 355-367, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485280
2.
Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model.
Mol Pharm
; 21(5): 2284-2297, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38529622
3.
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.
Pharm Res
; 41(3): 557-566, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38302834
4.
Modeling Pharmacokinetic Natural Product-Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach.
Pharmacol Rev
; 73(2): 847-859, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712517
5.
Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.
Drug Metab Dispos
; 51(11): 1483-1489, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562957
6.
Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.
Int J Mol Sci
; 24(13)2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446360
7.
Pandemic Response Officers: Integration Between Medical, Public Health, and Higher Education Systems to Expedite Prevention and Response.
J Public Health Manag Pract
; 29(4): 556-562, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36727770
8.
Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Phytother Res
; 35(6): 3286-3297, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587330
9.
A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model.
J Pharmacol Exp Ther
; 371(2): 385-393, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420525
10.
Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition.
Drug Metab Dispos
; 46(11): 1478-1486, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166404
11.
Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
Drug Metab Dispos
; 45(12): 1317-1325, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28986475
12.
Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease.
Liver Int
; 37(7): 1074-1081, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28097795
13.
In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice.
J Biochem Mol Toxicol
; 31(2)2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27712037
14.
Biliary Elimination of Pemetrexed Is Dependent on Mrp2 in Rats: Potential Mechanism of Variable Response in Nonalcoholic Steatohepatitis.
J Pharmacol Exp Ther
; 358(2): 246-53, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233293
15.
Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis.
J Pharmacol Exp Ther
; 352(3): 462-70, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512370
16.
Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis.
Drug Metab Dispos
; 43(2): 266-72, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488932
17.
Synergistic interaction between genetics and disease on pravastatin disposition.
J Hepatol
; 61(1): 139-47, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24613363
18.
Experimental nonalcoholic steatohepatitis increases exposure to simvastatin hydroxy acid by decreasing hepatic organic anion transporting polypeptide expression.
J Pharmacol Exp Ther
; 348(3): 452-8, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24403518
19.
Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice.
Drug Metab Dispos
; 42(4): 596-602, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24378326
20.
Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models.
Drug Metab Dispos
; 42(4): 586-95, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24384915