Detalhe da pesquisa
1.
Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.
Bioorg Med Chem Lett
; 20(15): 4359-63, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615696
2.
Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution.
Bioorg Med Chem Lett
; 18(16): 4573-7, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18662872
3.
Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes.
Pain
; 98(1-2): 109-17, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12098622
4.
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
J Med Chem
; 53(8): 3330-48, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20307063
5.
From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist.
Bioorg Med Chem Lett
; 16(19): 5217-21, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16870426