Detalhe da pesquisa
1.
Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
Am J Hum Genet
; 109(1): 81-96, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34932938
2.
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
Am J Hum Genet
; 109(5): 857-870, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35385699
3.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods
; 19(12): 1599-1611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36303018
4.
Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Blood
; 139(3): 357-368, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34855941
5.
ANNORE: genetic fine-mapping with functional annotation.
Hum Mol Genet
; 31(1): 32-40, 2021 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34302344
6.
The impact of obesity on lung function measurements and respiratory disease: A Mendelian randomization study.
Ann Hum Genet
; 87(4): 174-183, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37009668
7.
Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study.
Genet Epidemiol
; 45(6): 651-663, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34167169
8.
Rare coding variants in RCN3 are associated with blood pressure.
BMC Genomics
; 23(1): 148, 2022 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35183128
9.
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.
Am J Hum Genet
; 105(4): 706-718, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564435
10.
Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies.
Am J Hum Genet
; 104(2): 260-274, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639324
11.
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
PLoS Genet
; 15(12): e1008500, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31869403
12.
A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program.
Am J Epidemiol
; 190(10): 1977-1992, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861317
13.
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Mol Psychiatry
; 25(8): 1859-1875, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108311
14.
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Mol Psychiatry
; 25(8): 1901-1903, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31636380
15.
Revisiting methods for modeling longitudinal and survival data: Framingham Heart Study.
BMC Med Res Methodol
; 21(1): 29, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568059
16.
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.
PLoS Genet
; 14(4): e1007222, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29608557
17.
A fully adjusted two-stage procedure for rank-normalization in genetic association studies.
Genet Epidemiol
; 43(3): 263-275, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653739
18.
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study.
Pharmacogenomics J
; 20(3): 462-470, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31801993
19.
Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.
PLoS Genet
; 13(6): e1006812, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28614350
20.
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.
Genomics
; 111(4): 808-818, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29857119