Detalhe da pesquisa
1.
Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.
EMBO J
; 40(22): e108125, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34617326
2.
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia.
Mol Cancer
; 21(1): 35, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35120522
3.
Lipopolysaccharide and sphingosine-1-phosphate cooperate to induce inflammatory molecules and leukocyte adhesion in endothelial cells.
J Immunol
; 189(11): 5402-10, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23089395
4.
Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.
Oncogene
; 42(5): 389-405, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36476833
5.
Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.
Mol Oncol
; 16(19): 3533-3553, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895495
6.
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.
Cell Rep
; 38(11): 110522, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35294890
7.
Distinct Roles of Vav Family Members in Adaptive and Innate Immune Models of Arthritis.
Biomedicines
; 9(6)2021 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205377
8.
Rho guanosine nucleotide exchange factors are not such bad guys after all in cancera.
Small GTPases
; 11(4): 233-239, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29313423
9.
Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis.
Nat Commun
; 11(1): 5808, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199701
10.
Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.
Cardiovasc Res
; 79(3): 537-44, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18411230
11.
Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms.
Oncogene
; 38(2): 209-227, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30087437
12.
RAS GTPase-dependent pathways in developmental diseases: old guys, new lads, and current challenges.
Curr Opin Cell Biol
; 55: 42-51, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30007125
13.
An unexpected tumor suppressor role for VAV1a.
Mol Cell Oncol
; 5(3): e1432257, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30250888
14.
R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.
Sci Signal
; 11(532)2018 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29844052
15.
A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia.
Cancer Cell
; 32(5): 608-623.e9, 2017 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29136506
16.
Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells.
PLoS One
; 9(9): e109081, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275309
17.
Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells.
Int J Cardiol
; 158(1): 18-25, 2012 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21247641