Detalhe da pesquisa
1.
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema.
PLoS Genet
; 19(8): e1010609, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37585454
2.
Unraveling Pre-filled Syringe Needle Clogging: Exploring a Fresh Outlook Through Innovative Techniques.
Pharm Res
; 41(3): 547-556, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326531
3.
Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry.
Anal Chem
; 95(11): 4834-4839, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36876898
4.
USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature
; 550(7677): 534-538, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045385
5.
MiDAS-Meaningful Immunogenetic Data at Scale.
PLoS Comput Biol
; 17(7): e1009131, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228721
6.
Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes.
Drug Metab Dispos
; 49(9): 760-769, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187837
7.
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration.
Proc Natl Acad Sci U S A
; 115(50): E11701-E11710, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463956
8.
Characterizing and Quantitating Therapeutic Tethered Multimeric Antibody Degradation Using Affinity Capture Mass Spectrometry.
Anal Chem
; 92(10): 6839-6843, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32309925
9.
Probing in Vitro Release Kinetics of Long-Acting Injectable Nanosuspensions via Flow-NMR Spectroscopy.
Mol Pharm
; 17(2): 530-540, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31895571
10.
Interpreting In Vitro Release Performance from Long-Acting Parenteral Nanosuspensions Using USP-4 Dissolution and Spectroscopic Techniques.
Mol Pharm
; 17(5): 1734-1747, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267708
11.
Direct Drug Analysis in Polymeric Implants Using Desorption Electrospray Ionization - Mass Spectrometry Imaging (DESI-MSI).
Pharm Res
; 37(6): 107, 2020 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32462273
12.
Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms.
Genes Immun
; 20(2): 172-179, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29550837
13.
Dual functionality of ß-tryptase protomers as both proteases and cofactors in the active tetramer.
J Biol Chem
; 293(25): 9614-9628, 2018 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661938
14.
Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death.
Mol Cell Proteomics
; 15(7): 2293-307, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27125827
15.
USP Apparatus 4: a Valuable In Vitro Tool to Enable Formulation Development of Long-Acting Parenteral (LAP) Nanosuspension Formulations of Poorly Water-Soluble Compounds.
AAPS PharmSciTech
; 19(1): 413-424, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28755052
16.
Identifying and mitigating batch effects in whole genome sequencing data.
BMC Bioinformatics
; 18(1): 351, 2017 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28738841
17.
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
Proc Natl Acad Sci U S A
; 111(39): 14217-22, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225364
18.
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.
Proc Natl Acad Sci U S A
; 110(28): 11379-84, 2013 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801757
19.
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
Breast Cancer Res
; 17: 59, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902869
20.
Synthesis and Electronic Structure of Ru2(Xap)4(Y-gem-DEE) Type Compounds: Effect of Cross-Conjugation.
Inorg Chem
; 54(15): 7645-52, 2015 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26204103