Detalhe da pesquisa
1.
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
Proc Natl Acad Sci U S A
; 117(52): 33619-33627, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318177
2.
Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice.
J Neuroinflammation
; 17(1): 336, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33176797
3.
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.
Proc Natl Acad Sci U S A
; 114(19): E3839-E3848, 2017 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446616
4.
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.
Exp Eye Res
; 141: 42-56, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26116903
5.
DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.
Neurobiol Dis
; 69: 108-16, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24878510
6.
JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells.
Exp Eye Res
; 112: 106-17, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23648575
7.
BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells.
Mol Cell Neurosci
; 51(1-2): 53-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22836101
8.
Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19.
Nat Commun
; 14(1): 4481, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491352
9.
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.
Neurobiol Dis
; 46(2): 393-401, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22353563
10.
Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice.
Mol Brain
; 13(1): 81, 2020 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32450896
11.
Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.
Mol Neurodegener
; 14(1): 6, 2019 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670050
12.
Nicotinamide treatment robustly protects from inherited mouse glaucoma.
Commun Integr Biol
; 11(1): e1356956, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29497468
13.
Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.
Cell Death Dis
; 9(6): 705, 2018 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899326
14.
Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.
J Glaucoma
; 26(12): 1161-1168, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28858158
15.
Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.
Science
; 355(6326): 756-760, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28209901
16.
Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma.
Front Neurosci
; 11: 232, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28487632
17.
Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease.
Sci Rep
; 6: 21568, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888450
18.
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.
Nat Genet
; 47(4): 387-92, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25706626
19.
Animal models of exfoliation syndrome, now and future.
J Glaucoma
; 23(8 Suppl 1): S68-72, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275912
20.
The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice.
Sci Rep
; 2: 530, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22833783