Detalhe da pesquisa
1.
The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex.
Cell
; 180(4): 603-604, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32084338
2.
TRPV1 Activation by Anandamide via a Unique Lipid Pathway.
J Chem Inf Model
; 61(12): 5742-5746, 2021 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780173
3.
GPR6 Structural Insights: Homology Model Construction and Docking Studies.
Molecules
; 25(3)2020 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046081
4.
Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity.
Int J Mol Sci
; 20(9)2019 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31075933
5.
Identification of Crucial Amino Acid Residues Involved in Agonist Signaling at the GPR55 Receptor.
Biochemistry
; 56(3): 473-486, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28005346
6.
Structure-activity relationships of benzothiazole GPR35 antagonists.
Bioorg Med Chem Lett
; 27(3): 612-615, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989666
7.
Design, synthesis and biological evaluation of GPR55 agonists.
Bioorg Med Chem
; 25(16): 4355-4367, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673732
8.
A dual substrate kinetic model for cytochrome P450BM3-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol.
Biotechnol Lett
; 39(2): 311-321, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864654
9.
Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior.
J Neurosci
; 35(41): 13975-88, 2015 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26468198
10.
Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones.
Bioorg Med Chem Lett
; 26(7): 1827-1830, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26916440
11.
(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.
Mol Pharmacol
; 87(2): 197-206, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411367
12.
Crucial positively charged residues for ligand activation of the GPR35 receptor.
J Biol Chem
; 289(6): 3625-38, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24347166
13.
Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complex.
J Biol Chem
; 289(29): 20259-72, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24855641
14.
Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues.
Bioorg Med Chem
; 23(21): 6993-9, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26481152
15.
Global fold of human cannabinoid type 2 receptor probed by solid-state 13C-, 15N-MAS NMR and molecular dynamics simulations.
Proteins
; 82(3): 452-65, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999926
16.
Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.
Biochemistry
; 52(52): 9456-69, 2013 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24274581
17.
Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship.
ACS Med Chem Lett
; 14(1): 18-25, 2023 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36655130
18.
The NPXXY Motif Regulates ß-Arrestin Recruitment by the CB1 Cannabinoid Receptor.
Cannabis Cannabinoid Res
; 8(5): 731-748, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35792570
19.
Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors.
Eur J Med Chem
; 249: 115123, 2023 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36708677
20.
Palmitoylation and membrane cholesterol stabilize µ-opioid receptor homodimerization and G protein coupling.
BMC Cell Biol
; 13: 6, 2012 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22429589